DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class0
GeneSetA-674563_KINOME SCAN
Enrichment Score (ES)-0.23230726
Normalized Enrichment Score (NES)-0.8267283
Nominal p-value0.79802954
FDR q-value0.94442
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: A-674563_KINOME SCAN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1PAK6PAK6
Entrez,  Source
p21(CDKN1A)-activated kinase 61580.4590.0629No
2PRKCDPRKCD
Entrez,  Source
protein kinase C, delta3060.3370.1066No
3PRKCHPRKCH
Entrez,  Source
protein kinase C, eta3560.3090.1534No
4CDK146590.2220.1665No
5TNIKTNIK
Entrez,  Source
TRAF2 and NCK interacting kinase11970.1450.1493No
6DYRK2DYRK2
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 212300.1420.1701No
7GAKGAK
Entrez,  Source
cyclin G associated kinase13400.1330.1836No
8CAMK2ACAMK2A
Entrez,  Source
calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha18010.1070.1660No
9CAMK2GCAMK2G
Entrez,  Source
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma18110.1070.1827No
10CSNK1DCSNK1D
Entrez,  Source
casein kinase 1, delta18510.1050.1968No
11RIOK3RIOK3
Entrez,  Source
RIO kinase 3 (yeast)19420.1010.2065No
12AAK1AAK1
Entrez,  Source
AP2 associated kinase 122120.0920.2010No
13CLK3CLK3
Entrez,  Source
CDC-like kinase 323490.0870.2049No
14TAOK1TAOK1
Entrez,  Source
TAO kinase 125520.0820.2028No
15PIM2PIM2
Entrez,  Source
pim-2 oncogene29560.0710.1838No
16MINK1MINK1
Entrez,  Source
misshapen-like kinase 1 (zebrafish)30800.0690.1857No
17FLT3FLT3
Entrez,  Source
fms-related tyrosine kinase 334030.0630.1713No
18PRKG2PRKG2
Entrez,  Source
protein kinase, cGMP-dependent, type II40210.0520.1328No
19PIM1PIM1
Entrez,  Source
pim-1 oncogene41360.0500.1323No
20CAMK2BCAMK2B
Entrez,  Source
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta42130.0490.1345No
21CDKL5CDKL5
Entrez,  Source
cyclin-dependent kinase-like 543450.0470.1322No
22CDKL2CDKL2
Entrez,  Source
cyclin-dependent kinase-like 2 (CDC2-related kinase)45480.0440.1240No
23PRKG1PRKG1
Entrez,  Source
protein kinase, cGMP-dependent, type I49360.0380.1007No
24PAK4PAK4
Entrez,  Source
p21(CDKN1A)-activated kinase 450140.0370.1009No
25PAK7PAK7
Entrez,  Source
p21(CDKN1A)-activated kinase 758810.0250.0391No
26PRKXPRKX
Entrez,  Source
protein kinase, X-linked59930.0240.0345No
27CSNK1G2CSNK1G2
Entrez,  Source
casein kinase 1, gamma 263280.0180.0120No
28CAMK4CAMK4
Entrez,  Source
calcium/calmodulin-dependent protein kinase IV63930.0170.0100No
29RETRET
Entrez,  Source
ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)64710.0160.0068No
30PKN1PKN1
Entrez,  Source
protein kinase N167830.012-0.0150No
31CLK4CLK4
Entrez,  Source
CDC-like kinase 469350.010-0.0250No
32BMP2KBMP2K
Entrez,  Source
BMP2 inducible kinase70290.008-0.0308No
33CLK2CLK2
Entrez,  Source
CDC-like kinase 271810.005-0.0414No
34AKT1AKT1
Entrez,  Source
v-akt murine thymoma viral oncogene homolog 173870.002-0.0568No
35CSNK1ECSNK1E
Entrez,  Source
casein kinase 1, epsilon7742-0.004-0.0830No
36MELKMELK
Entrez,  Source
maternal embryonic leucine zipper kinase8047-0.010-0.1046No
37PRKACAPRKACA
Entrez,  Source
protein kinase, cAMP-dependent, catalytic, alpha8112-0.011-0.1077No
38KITKIT
Entrez,  Source
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog8134-0.012-0.1073No
39DYRK1BDYRK1B
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B8200-0.013-0.1102No
40DMPKDMPK
Entrez,  Source
dystrophia myotonica-protein kinase8344-0.016-0.1184No
41CSNK1G1CSNK1G1
Entrez,  Source
casein kinase 1, gamma 18732-0.025-0.1439No
42ROCK1ROCK1
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 18741-0.025-0.1405No
43HIPK3HIPK3
Entrez,  Source
homeodomain interacting protein kinase 39770-0.050-0.2107No
44MAP4K4MAP4K4
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 49922-0.055-0.2134No
45HIPK2HIPK2
Entrez,  Source
homeodomain interacting protein kinase 210151-0.061-0.2208No
46DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A10303-0.066-0.2215Yes
47CITCIT
Entrez,  Source
citron (rho-interacting, serine/threonine kinase 21)10420-0.070-0.2190Yes
48ICKICK
Entrez,  Source
intestinal cell (MAK-like) kinase10499-0.073-0.2131Yes
49CAMKK2CAMKK2
Entrez,  Source
calcium/calmodulin-dependent protein kinase kinase 2, beta10729-0.081-0.2173Yes
50PIP5K1APIP5K1A
Entrez,  Source
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha10780-0.083-0.2074Yes
51PRKCEPRKCE
Entrez,  Source
protein kinase C, epsilon10801-0.084-0.1952Yes
52PRKCQPRKCQ
Entrez,  Source
protein kinase C, theta10961-0.092-0.1923Yes
53SRPK1SRPK1
Entrez,  Source
SFRS protein kinase 111068-0.096-0.1847Yes
54GSK3BGSK3B
Entrez,  Source
glycogen synthase kinase 3 beta11131-0.100-0.1731Yes
55CDK7CDK7
Entrez,  Source
cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)11160-0.101-0.1588Yes
56PRKACBPRKACB
Entrez,  Source
protein kinase, cAMP-dependent, catalytic, beta11179-0.102-0.1435Yes
57MYLKMYLK
Entrez,  Source
myosin, light chain kinase11255-0.105-0.1321Yes
58CDK9CDK9
Entrez,  Source
cyclin-dependent kinase 9 (CDC2-related kinase)11631-0.125-0.1403Yes
59HIPK1HIPK1
Entrez,  Source
homeodomain interacting protein kinase 111798-0.135-0.1308Yes
60CDC42BPACDC42BPA
Entrez,  Source
CDC42 binding protein kinase alpha (DMPK-like)11941-0.145-0.1180Yes
61CDC42BPBCDC42BPB
Entrez,  Source
CDC42 binding protein kinase beta (DMPK-like)12053-0.154-0.1013Yes
62PKN2PKN2
Entrez,  Source
protein kinase N212286-0.175-0.0904Yes
63CSNK1G3CSNK1G3
Entrez,  Source
casein kinase 1, gamma 312464-0.197-0.0717Yes
64AKT3AKT3
Entrez,  Source
v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)12533-0.207-0.0430Yes
65MAP3K7MAP3K7
Entrez,  Source
mitogen-activated protein kinase kinase kinase 712613-0.221-0.0130Yes
66PRKD3PRKD3
Entrez,  Source
protein kinase D313008-0.3450.0133Yes
Table: GSEA details [plain text format]



Fig 2: A-674563_KINOME SCAN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: A-674563_KINOME SCAN: Random ES distribution   
Gene set null distribution of ES for A-674563_KINOME SCAN