DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class0
GeneSetK-252A, NOCARDIOPSIS SP._RBC
Enrichment Score (ES)-0.22862504
Normalized Enrichment Score (NES)-0.8960608
Nominal p-value0.72252744
FDR q-value0.88672286
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: K-252A, NOCARDIOPSIS SP._RBC   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1PRKCDPRKCD
Entrez,  Source
protein kinase C, delta3060.3370.0146No
2SYKSYK
Entrez,  Source
spleen tyrosine kinase4710.2680.0323No
3ROS1ROS1
Entrez,  Source
v-ros UR2 sarcoma virus oncogene homolog 1 (avian)5050.2580.0589No
4RPS6KA2RPS6KA2
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 25900.2370.0792No
5PAK1PAK1
Entrez,  Source
p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)6740.2190.0975No
6DYRK2DYRK2
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 212300.1420.0711No
7STK3STK3
Entrez,  Source
serine/threonine kinase 3 (STE20 homolog, yeast)15530.1200.0600No
8RPS6KA1RPS6KA1
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 116860.1130.0626No
9MAP3K9MAP3K9
Entrez,  Source
mitogen-activated protein kinase kinase kinase 916990.1120.0744No
10NTRK2NTRK2
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 217040.1120.0867No
11CAMK2ACAMK2A
Entrez,  Source
calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha18010.1070.0914No
12CAMK2GCAMK2G
Entrez,  Source
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma18110.1070.1028No
13MAP3K5MAP3K5
Entrez,  Source
mitogen-activated protein kinase kinase kinase 521470.0940.0878No
14MARK1MARK1
Entrez,  Source
MAP/microtubule affinity-regulating kinase 121590.0930.0975No
15ULK2ULK2
Entrez,  Source
unc-51-like kinase 2 (C. elegans)22440.0910.1013No
16MAP3K11MAP3K11
Entrez,  Source
mitogen-activated protein kinase kinase kinase 1122950.0890.1075No
17JAK3JAK3
Entrez,  Source
Janus kinase 3 (a protein tyrosine kinase, leukocyte)24440.0840.1057No
18MERTKMERTK
Entrez,  Source
c-mer proto-oncogene tyrosine kinase25220.0820.1091No
19RPS6KA5RPS6KA5
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 526100.0800.1115No
20STK38STK38
Entrez,  Source
serine/threonine kinase 3828780.0730.0994No
21MKNK1MKNK1
Entrez,  Source
MAP kinase interacting serine/threonine kinase 129070.0730.1054No
22TNK2TNK2
Entrez,  Source
tyrosine kinase, non-receptor, 230050.0700.1060No
23MINK1MINK1
Entrez,  Source
misshapen-like kinase 1 (zebrafish)30800.0690.1081No
24PRKACGPRKACG
Entrez,  Source
protein kinase, cAMP-dependent, catalytic, gamma32240.0660.1046No
25FLT3FLT3
Entrez,  Source
fms-related tyrosine kinase 334030.0630.0981No
26TSSK1B34450.0620.1019No
27PASKPASK
Entrez,  Source
PAS domain containing serine/threonine kinase34930.0610.1052No
28MARK2MARK2
Entrez,  Source
MAP/microtubule affinity-regulating kinase 238340.0550.0854No
29PRKD2PRKD2
Entrez,  Source
protein kinase D239000.0540.0865No
30PRKG2PRKG2
Entrez,  Source
protein kinase, cGMP-dependent, type II40210.0520.0832No
31ALKALK
Entrez,  Source
anaplastic lymphoma kinase (Ki-1)40730.0510.0851No
32MUSKMUSK
Entrez,  Source
muscle, skeletal, receptor tyrosine kinase41390.0500.0858No
33FGRFGR
Entrez,  Source
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog41930.0490.0873No
34CAMK2BCAMK2B
Entrez,  Source
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta42130.0490.0913No
35AURKCAURKC
Entrez,  Source
aurora kinase C44130.0460.0813No
36LIMK1LIMK1
Entrez,  Source
LIM domain kinase 144680.0450.0823No
37RPS6KA6RPS6KA6
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 646850.0420.0705No
38PHKG2PHKG2
Entrez,  Source
phosphorylase kinase, gamma 2 (testis)47920.0400.0670No
39BMXBMX
Entrez,  Source
BMX non-receptor tyrosine kinase48260.0400.0689No
40FLT4FLT4
Entrez,  Source
fms-related tyrosine kinase 448980.0390.0679No
41PRKG1PRKG1
Entrez,  Source
protein kinase, cGMP-dependent, type I49360.0380.0694No
42INSRRINSRR
Entrez,  Source
insulin receptor-related receptor53320.0330.0429No
43SGK2SGK2
Entrez,  Source
serum/glucocorticoid regulated kinase 255180.0310.0322No
44BTKBTK
Entrez,  Source
Bruton agammaglobulinemia tyrosine kinase56280.0290.0271No
45MAP3K3MAP3K3
Entrez,  Source
mitogen-activated protein kinase kinase kinase 359210.0250.0075No
46PRKXPRKX
Entrez,  Source
protein kinase, X-linked59930.0240.0048No
47NTRK1NTRK1
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 160970.022-0.0006No
48IRAK1IRAK1
Entrez,  Source
interleukin-1 receptor-associated kinase 161790.021-0.0045No
49PHKG1PHKG1
Entrez,  Source
phosphorylase kinase, gamma 1 (muscle)62450.020-0.0072No
50AURKAAURKA
Entrez,  Source
aurora kinase A64270.017-0.0191No
51RETRET
Entrez,  Source
ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)64710.016-0.0206No
52MAP3K10MAP3K10
Entrez,  Source
mitogen-activated protein kinase kinase kinase 1065490.015-0.0247No
53PKN1PKN1
Entrez,  Source
protein kinase N167830.012-0.0412No
54MAP4K2MAP4K2
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 268940.010-0.0485No
55PRKCB69340.010-0.0504No
56CLK4CLK4
Entrez,  Source
CDC-like kinase 469350.010-0.0493No
57CLK2CLK2
Entrez,  Source
CDC-like kinase 271810.005-0.0675No
58IKBKEIKBKE
Entrez,  Source
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon72160.004-0.0696No
59CDK5CDK5
Entrez,  Source
cyclin-dependent kinase 574320.001-0.0859No
60SIK274350.001-0.0860No
61PDGFRBPDGFRB
Entrez,  Source
platelet-derived growth factor receptor, beta polypeptide7824-0.006-0.1150No
62MAPK9MAPK9
Entrez,  Source
mitogen-activated protein kinase 97830-0.006-0.1147No
63MKNK2MKNK2
Entrez,  Source
MAP kinase interacting serine/threonine kinase 27841-0.006-0.1148No
64MELKMELK
Entrez,  Source
maternal embryonic leucine zipper kinase8047-0.010-0.1293No
65LTKLTK
Entrez,  Source
leukocyte tyrosine kinase8158-0.012-0.1364No
66RPS6KA4RPS6KA4
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 48181-0.013-0.1366No
67DYRK1BDYRK1B
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B8200-0.013-0.1365No
68MARK4MARK4
Entrez,  Source
MAP/microtubule affinity-regulating kinase 48259-0.014-0.1393No
69PDK1PDK1
Entrez,  Source
pyruvate dehydrogenase kinase, isozyme 18449-0.018-0.1517No
70NTRK3NTRK3
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 38500-0.019-0.1534No
71AURKBAURKB
Entrez,  Source
aurora kinase B8856-0.027-0.1774No
72IRAK4IRAK4
Entrez,  Source
interleukin-1 receptor-associated kinase 48996-0.031-0.1846No
73MAPKAPK2MAPKAPK2
Entrez,  Source
mitogen-activated protein kinase-activated protein kinase 29187-0.035-0.1952No
74CDK2CDK2
Entrez,  Source
cyclin-dependent kinase 29409-0.040-0.2076No
75TYK2TYK2
Entrez,  Source
tyrosine kinase 29438-0.041-0.2051No
76PAK3PAK3
Entrez,  Source
p21 (CDKN1A)-activated kinase 39490-0.042-0.2042No
77NEK9NEK9
Entrez,  Source
NIMA (never in mitosis gene a)- related kinase 99810-0.051-0.2229Yes
78PRKD1PRKD1
Entrez,  Source
protein kinase D19827-0.052-0.2183Yes
79CDK6CDK6
Entrez,  Source
cyclin-dependent kinase 69834-0.052-0.2129Yes
80MAP4K4MAP4K4
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 49922-0.055-0.2134Yes
81HCKHCK
Entrez,  Source
hemopoietic cell kinase9981-0.056-0.2115Yes
82STK17ASTK17A
Entrez,  Source
serine/threonine kinase 17a (apoptosis-inducing)10017-0.057-0.2077Yes
83CHEK2CHEK2
Entrez,  Source
CHK2 checkpoint homolog (S. pombe)10102-0.059-0.2075Yes
84DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A10303-0.066-0.2153Yes
85MARK3MARK3
Entrez,  Source
MAP/microtubule affinity-regulating kinase 310374-0.068-0.2130Yes
86RPS6KA3RPS6KA3
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 310427-0.070-0.2090Yes
87JAK1JAK1
Entrez,  Source
Janus kinase 1 (a protein tyrosine kinase)10585-0.076-0.2125Yes
88RPS6KB1RPS6KB1
Entrez,  Source
ribosomal protein S6 kinase, 70kDa, polypeptide 110717-0.081-0.2134Yes
89CAMKK2CAMKK2
Entrez,  Source
calcium/calmodulin-dependent protein kinase kinase 2, beta10729-0.081-0.2051Yes
90TBK1TBK1
Entrez,  Source
TANK-binding kinase 110732-0.082-0.1960Yes
91BRSK2BRSK2
Entrez,  Source
BR serine/threonine kinase 210749-0.082-0.1880Yes
92CHEK1CHEK1
Entrez,  Source
CHK1 checkpoint homolog (S. pombe)10792-0.084-0.1817Yes
93PRKCEPRKCE
Entrez,  Source
protein kinase C, epsilon10801-0.084-0.1728Yes
94PAK2PAK2
Entrez,  Source
p21 (CDKN1A)-activated kinase 210809-0.085-0.1638Yes
95CDK4CDK4
Entrez,  Source
cyclin-dependent kinase 410871-0.087-0.1586Yes
96NUAK1NUAK1
Entrez,  Source
NUAK family, SNF1-like kinase, 111032-0.095-0.1602Yes
97PBKPBK
Entrez,  Source
PDZ binding kinase11092-0.098-0.1537Yes
98STK10STK10
Entrez,  Source
serine/threonine kinase 1011218-0.103-0.1516Yes
99MYLKMYLK
Entrez,  Source
myosin, light chain kinase11255-0.105-0.1425Yes
100RIPK2RIPK2
Entrez,  Source
receptor-interacting serine-threonine kinase 211349-0.110-0.1372Yes
101FERFER
Entrez,  Source
fer (fps/fes related) tyrosine kinase (phosphoprotein NCP94)11371-0.111-0.1264Yes
102STK4STK4
Entrez,  Source
serine/threonine kinase 411518-0.118-0.1242Yes
103JAK2JAK2
Entrez,  Source
Janus kinase 2 (a protein tyrosine kinase)11530-0.119-0.1117Yes
104TLK2TLK2
Entrez,  Source
tousled-like kinase 211621-0.124-0.1045Yes
105SLKSLK
Entrez,  Source
STE20-like kinase (yeast)11672-0.128-0.0940Yes
106MAP4K5MAP4K5
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 511705-0.130-0.0818Yes
107MAP2K6MAP2K6
Entrez,  Source
mitogen-activated protein kinase kinase 611934-0.144-0.0829Yes
108MAP3K2MAP3K2
Entrez,  Source
mitogen-activated protein kinase kinase kinase 212210-0.168-0.0850Yes
109DYRK3DYRK3
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 312238-0.171-0.0678Yes
110PKN2PKN2
Entrez,  Source
protein kinase N212286-0.175-0.0517Yes
111MAP3K7MAP3K7
Entrez,  Source
mitogen-activated protein kinase kinase kinase 712613-0.221-0.0517Yes
112PRKD3PRKD3
Entrez,  Source
protein kinase D313008-0.345-0.0429Yes
113SGK113133-0.4980.0037Yes
Table: GSEA details [plain text format]



Fig 2: K-252A, NOCARDIOPSIS SP._RBC   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: K-252A, NOCARDIOPSIS SP._RBC: Random ES distribution   
Gene set null distribution of ES for K-252A, NOCARDIOPSIS SP._RBC