DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class0
GeneSetSB 218078_RBC
Enrichment Score (ES)-0.2587787
Normalized Enrichment Score (NES)-0.9410844
Nominal p-value0.58472556
FDR q-value0.9071905
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: SB 218078_RBC   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1ROS1ROS1
Entrez,  Source
v-ros UR2 sarcoma virus oncogene homolog 1 (avian)5050.2580.0054No
2RPS6KA2RPS6KA2
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 25900.2370.0395No
3DYRK2DYRK2
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 212300.1420.0150No
4STK3STK3
Entrez,  Source
serine/threonine kinase 3 (STE20 homolog, yeast)15530.1200.0108No
5RPS6KA1RPS6KA1
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 116860.1130.0200No
6MAP3K9MAP3K9
Entrez,  Source
mitogen-activated protein kinase kinase kinase 916990.1120.0383No
7NTRK2NTRK2
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 217040.1120.0571No
8CAMK2ACAMK2A
Entrez,  Source
calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha18010.1070.0680No
9CAMK2GCAMK2G
Entrez,  Source
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma18110.1070.0856No
10MARK1MARK1
Entrez,  Source
MAP/microtubule affinity-regulating kinase 121590.0930.0750No
11MAP3K11MAP3K11
Entrez,  Source
mitogen-activated protein kinase kinase kinase 1122950.0890.0799No
12JAK3JAK3
Entrez,  Source
Janus kinase 3 (a protein tyrosine kinase, leukocyte)24440.0840.0830No
13MERTKMERTK
Entrez,  Source
c-mer proto-oncogene tyrosine kinase25220.0820.0912No
14RPS6KA5RPS6KA5
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 526100.0800.0982No
15PIM2PIM2
Entrez,  Source
pim-2 oncogene29560.0710.0841No
16TNK2TNK2
Entrez,  Source
tyrosine kinase, non-receptor, 230050.0700.0924No
17MINK1MINK1
Entrez,  Source
misshapen-like kinase 1 (zebrafish)30800.0690.0986No
18KDRKDR
Entrez,  Source
kinase insert domain receptor (a type III receptor tyrosine kinase)31460.0680.1052No
19FLT3FLT3
Entrez,  Source
fms-related tyrosine kinase 334030.0630.0963No
20MARK2MARK2
Entrez,  Source
MAP/microtubule affinity-regulating kinase 238340.0550.0729No
21PRKD2PRKD2
Entrez,  Source
protein kinase D239000.0540.0771No
22PRKG2PRKG2
Entrez,  Source
protein kinase, cGMP-dependent, type II40210.0520.0769No
23PIM1PIM1
Entrez,  Source
pim-1 oncogene41360.0500.0767No
24CAMK2BCAMK2B
Entrez,  Source
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta42130.0490.0793No
25RPS6KA6RPS6KA6
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 646850.0420.0505No
26FLT1FLT1
Entrez,  Source
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)48820.0390.0422No
27FLT4FLT4
Entrez,  Source
fms-related tyrosine kinase 448980.0390.0477No
28INSRRINSRR
Entrez,  Source
insulin receptor-related receptor53320.0330.0203No
29STK24STK24
Entrez,  Source
serine/threonine kinase 24 (STE20 homolog, yeast)55870.0290.0059No
30NTRK1NTRK1
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 160970.022-0.0291No
31PHKG1PHKG1
Entrez,  Source
phosphorylase kinase, gamma 1 (muscle)62450.020-0.0370No
32RETRET
Entrez,  Source
ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)64710.016-0.0513No
33MAP3K10MAP3K10
Entrez,  Source
mitogen-activated protein kinase kinase kinase 1065490.015-0.0546No
34PKN1PKN1
Entrez,  Source
protein kinase N167830.012-0.0704No
35MAP4K2MAP4K2
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 268940.010-0.0770No
36PRKCB69340.010-0.0784No
37ITKITK
Entrez,  Source
IL2-inducible T-cell kinase72200.004-0.0994No
38GSK3AGSK3A
Entrez,  Source
glycogen synthase kinase 3 alpha73580.002-0.1094No
39MKNK2MKNK2
Entrez,  Source
MAP kinase interacting serine/threonine kinase 27841-0.006-0.1451No
40MELKMELK
Entrez,  Source
maternal embryonic leucine zipper kinase8047-0.010-0.1591No
41RPS6KA4RPS6KA4
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 48181-0.013-0.1671No
42DYRK1BDYRK1B
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B8200-0.013-0.1662No
43MARK4MARK4
Entrez,  Source
MAP/microtubule affinity-regulating kinase 48259-0.014-0.1682No
44PDK1PDK1
Entrez,  Source
pyruvate dehydrogenase kinase, isozyme 18449-0.018-0.1795No
45NTRK3NTRK3
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 38500-0.019-0.1800No
46AURKBAURKB
Entrez,  Source
aurora kinase B8856-0.027-0.2024No
47IRAK4IRAK4
Entrez,  Source
interleukin-1 receptor-associated kinase 48996-0.031-0.2078No
48TYK2TYK2
Entrez,  Source
tyrosine kinase 29438-0.041-0.2344No
49CSNK2A2CSNK2A2
Entrez,  Source
casein kinase 2, alpha prime polypeptide9758-0.049-0.2504Yes
50PRKD1PRKD1
Entrez,  Source
protein kinase D19827-0.052-0.2468Yes
51CDK6CDK6
Entrez,  Source
cyclin-dependent kinase 69834-0.052-0.2384Yes
52MAP4K4MAP4K4
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 49922-0.055-0.2357Yes
53STK17ASTK17A
Entrez,  Source
serine/threonine kinase 17a (apoptosis-inducing)10017-0.057-0.2331Yes
54CHEK2CHEK2
Entrez,  Source
CHK2 checkpoint homolog (S. pombe)10102-0.059-0.2294Yes
55DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A10303-0.066-0.2334Yes
56MARK3MARK3
Entrez,  Source
MAP/microtubule affinity-regulating kinase 310374-0.068-0.2271Yes
57RPS6KA3RPS6KA3
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 310427-0.070-0.2191Yes
58RPS6KB1RPS6KB1
Entrez,  Source
ribosomal protein S6 kinase, 70kDa, polypeptide 110717-0.081-0.2273Yes
59CAMKK2CAMKK2
Entrez,  Source
calcium/calmodulin-dependent protein kinase kinase 2, beta10729-0.081-0.2143Yes
60TBK1TBK1
Entrez,  Source
TANK-binding kinase 110732-0.082-0.2005Yes
61BRSK2BRSK2
Entrez,  Source
BR serine/threonine kinase 210749-0.082-0.1878Yes
62CHEK1CHEK1
Entrez,  Source
CHK1 checkpoint homolog (S. pombe)10792-0.084-0.1766Yes
63CDK4CDK4
Entrez,  Source
cyclin-dependent kinase 410871-0.087-0.1677Yes
64NUAK1NUAK1
Entrez,  Source
NUAK family, SNF1-like kinase, 111032-0.095-0.1637Yes
65GSK3BGSK3B
Entrez,  Source
glycogen synthase kinase 3 beta11131-0.100-0.1542Yes
66STK10STK10
Entrez,  Source
serine/threonine kinase 1011218-0.103-0.1431Yes
67MYLKMYLK
Entrez,  Source
myosin, light chain kinase11255-0.105-0.1280Yes
68FERFER
Entrez,  Source
fer (fps/fes related) tyrosine kinase (phosphoprotein NCP94)11371-0.111-0.1179Yes
69STK4STK4
Entrez,  Source
serine/threonine kinase 411518-0.118-0.1089Yes
70JAK2JAK2
Entrez,  Source
Janus kinase 2 (a protein tyrosine kinase)11530-0.119-0.0895Yes
71TLK2TLK2
Entrez,  Source
tousled-like kinase 211621-0.124-0.0751Yes
72CDK9CDK9
Entrez,  Source
cyclin-dependent kinase 9 (CDC2-related kinase)11631-0.125-0.0544Yes
73MAP4K5MAP4K5
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 511705-0.130-0.0378Yes
74PRKCAPRKCA
Entrez,  Source
protein kinase C, alpha11975-0.147-0.0333Yes
75MAP3K2MAP3K2
Entrez,  Source
mitogen-activated protein kinase kinase kinase 212210-0.168-0.0225Yes
76MAP3K7MAP3K7
Entrez,  Source
mitogen-activated protein kinase kinase kinase 712613-0.221-0.0155Yes
77PRKD3PRKD3
Entrez,  Source
protein kinase D313008-0.3450.0133Yes
Table: GSEA details [plain text format]



Fig 2: SB 218078_RBC   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: SB 218078_RBC: Random ES distribution   
Gene set null distribution of ES for SB 218078_RBC