DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class1
GeneSetAG1478_LINCS
Enrichment Score (ES)0.45062503
Normalized Enrichment Score (NES)1.2707323
Nominal p-value0.15018316
FDR q-value0.65581906
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: AG1478_LINCS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1ERBB2ERBB2
Entrez,  Source
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)1000.5370.1712Yes
2DDR1DDR1
Entrez,  Source
discoidin domain receptor family, member 12120.4040.2971Yes
3EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)6250.2300.3423Yes
4MAPK10MAPK10
Entrez,  Source
mitogen-activated protein kinase 1010690.1570.3610Yes
5LCKLCK
Entrez,  Source
lymphocyte-specific protein tyrosine kinase13100.1360.3880Yes
6GAKGAK
Entrez,  Source
cyclin G associated kinase13400.1330.4300Yes
7ERBB4ERBB4
Entrez,  Source
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)18130.1070.4296Yes
8LYNLYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog19740.1000.4506Yes
9MKNK1MKNK1
Entrez,  Source
MAP kinase interacting serine/threonine kinase 129070.0730.4040No
10FLT3FLT3
Entrez,  Source
fms-related tyrosine kinase 334030.0630.3872No
11BLKBLK
Entrez,  Source
B lymphoid tyrosine kinase34190.0620.4067No
12PIK3C2BPIK3C2B
Entrez,  Source
phosphoinositide-3-kinase, class 2, beta polypeptide54150.0320.2657No
13MAP3K3MAP3K3
Entrez,  Source
mitogen-activated protein kinase kinase kinase 359210.0250.2355No
14IRAK1IRAK1
Entrez,  Source
interleukin-1 receptor-associated kinase 161790.0210.2229No
15RETRET
Entrez,  Source
ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)64710.0160.2063No
16PIP5K1CPIP5K1C
Entrez,  Source
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma68810.0100.1786No
17MKNK2MKNK2
Entrez,  Source
MAP kinase interacting serine/threonine kinase 27841-0.0060.1078No
18MAP2K5MAP2K5
Entrez,  Source
mitogen-activated protein kinase kinase 58199-0.0130.0850No
19IRAK4IRAK4
Entrez,  Source
interleukin-1 receptor-associated kinase 48996-0.0310.0347No
20HCKHCK
Entrez,  Source
hemopoietic cell kinase9981-0.056-0.0214No
21CHEK2CHEK2
Entrez,  Source
CHK2 checkpoint homolog (S. pombe)10102-0.059-0.0108No
22BUB1BUB1
Entrez,  Source
BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast)10160-0.0610.0052No
23CITCIT
Entrez,  Source
citron (rho-interacting, serine/threonine kinase 21)10420-0.0700.0088No
24SRCSRC
Entrez,  Source
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)10776-0.0830.0095No
25MAPKAPK5MAPKAPK5
Entrez,  Source
mitogen-activated protein kinase-activated protein kinase 510962-0.0920.0260No
26STK10STK10
Entrez,  Source
serine/threonine kinase 1011218-0.1030.0411No
27SLKSLK
Entrez,  Source
STE20-like kinase (yeast)11672-0.1280.0491No
28ABL1ABL1
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 112463-0.1970.0547No
Table: GSEA details [plain text format]



Fig 2: AG1478_LINCS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: AG1478_LINCS: Random ES distribution   
Gene set null distribution of ES for AG1478_LINCS