DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class1
GeneSetGENENTECH LRRK2 INHIBITOR COMPOUND 18 (GNE-7915)_MRC
Enrichment Score (ES)0.45871237
Normalized Enrichment Score (NES)1.2100571
Nominal p-value0.26118067
FDR q-value0.6325316
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: GENENTECH LRRK2 INHIBITOR COMPOUND 18 (GNE-7915)_MRC   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1DAPK1DAPK1
Entrez,  Source
death-associated protein kinase 1880.5570.2194Yes
2PTK6PTK6
Entrez,  Source
PTK6 protein tyrosine kinase 61410.4790.4099Yes
3INSRINSR
Entrez,  Source
insulin receptor16640.1140.3406Yes
4RPS6KA1RPS6KA1
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 116860.1130.3848Yes
5MAP3K9MAP3K9
Entrez,  Source
mitogen-activated protein kinase kinase kinase 916990.1120.4295Yes
6MAP3K5MAP3K5
Entrez,  Source
mitogen-activated protein kinase kinase kinase 521470.0940.4337Yes
7MAP3K11MAP3K11
Entrez,  Source
mitogen-activated protein kinase kinase kinase 1122950.0890.4587Yes
8TSSK1B34450.0620.3966No
9FLT1FLT1
Entrez,  Source
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)48820.0390.3034No
10CLK2CLK2
Entrez,  Source
CDC-like kinase 271810.0050.1309No
11PHKA2PHKA2
Entrez,  Source
phosphorylase kinase, alpha 2 (liver)9057-0.0320.0014No
12PRKD1PRKD1
Entrez,  Source
protein kinase D19827-0.052-0.0361No
13CHEK2CHEK2
Entrez,  Source
CHK2 checkpoint homolog (S. pombe)10102-0.059-0.0329No
14RPS6KA3RPS6KA3
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 310427-0.070-0.0289No
15CAMKK2CAMKK2
Entrez,  Source
calcium/calmodulin-dependent protein kinase kinase 2, beta10729-0.081-0.0187No
16CHEK1CHEK1
Entrez,  Source
CHK1 checkpoint homolog (S. pombe)10792-0.0840.0107No
17NUAK1NUAK1
Entrez,  Source
NUAK family, SNF1-like kinase, 111032-0.0950.0310No
18MYLKMYLK
Entrez,  Source
myosin, light chain kinase11255-0.1050.0567No
19MAP3K7MAP3K7
Entrez,  Source
mitogen-activated protein kinase kinase kinase 712613-0.2210.0432No
Table: GSEA details [plain text format]



Fig 2: GENENTECH LRRK2 INHIBITOR COMPOUND 18 (GNE-7915)_MRC   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: GENENTECH LRRK2 INHIBITOR COMPOUND 18 (GNE-7915)_MRC: Random ES distribution   
Gene set null distribution of ES for GENENTECH LRRK2 INHIBITOR COMPOUND 18 (GNE-7915)_MRC