DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class1
GeneSetERLOTINIB_KINOME SCAN
Enrichment Score (ES)0.39604968
Normalized Enrichment Score (NES)1.1026006
Nominal p-value0.32417583
FDR q-value0.7296505
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: ERLOTINIB_KINOME SCAN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1DDR1DDR1
Entrez,  Source
discoidin domain receptor family, member 12120.4040.1302Yes
2EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)6250.2300.1824Yes
3LCKLCK
Entrez,  Source
lymphocyte-specific protein tyrosine kinase13100.1360.1796Yes
4GAKGAK
Entrez,  Source
cyclin G associated kinase13400.1330.2257Yes
5TNK1TNK1
Entrez,  Source
tyrosine kinase, non-receptor, 113600.1310.2719Yes
6PIP4K2C16760.1140.2891Yes
7ERBB4ERBB4
Entrez,  Source
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)18130.1070.3175Yes
8LYNLYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog19740.1000.3414Yes
9TIE1TIE1
Entrez,  Source
tyrosine kinase with immunoglobulin-like and EGF-like domains 123280.0880.3465Yes
10JAK3JAK3
Entrez,  Source
Janus kinase 3 (a protein tyrosine kinase, leukocyte)24440.0840.3683Yes
11MERTKMERTK
Entrez,  Source
c-mer proto-oncogene tyrosine kinase25220.0820.3924Yes
12MKNK1MKNK1
Entrez,  Source
MAP kinase interacting serine/threonine kinase 129070.0730.3896Yes
13FLT3FLT3
Entrez,  Source
fms-related tyrosine kinase 334030.0630.3746Yes
14BLKBLK
Entrez,  Source
B lymphoid tyrosine kinase34190.0620.3960Yes
15AURKCAURKC
Entrez,  Source
aurora kinase C44130.0460.3372No
16TNNI3KTNNI3K
Entrez,  Source
TNNI3 interacting kinase52740.0330.2840No
17EPHA5EPHA5
Entrez,  Source
EPH receptor A554750.0310.2800No
18RETRET
Entrez,  Source
ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)64710.0160.2103No
19CSNK1ECSNK1E
Entrez,  Source
casein kinase 1, epsilon7742-0.0040.1153No
20MKNK2MKNK2
Entrez,  Source
MAP kinase interacting serine/threonine kinase 27841-0.0060.1102No
21LTKLTK
Entrez,  Source
leukocyte tyrosine kinase8158-0.0120.0906No
22MAP2K5MAP2K5
Entrez,  Source
mitogen-activated protein kinase kinase 58199-0.0130.0923No
23CITCIT
Entrez,  Source
citron (rho-interacting, serine/threonine kinase 21)10420-0.070-0.0511No
24SRCSRC
Entrez,  Source
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)10776-0.083-0.0479No
25ABL2ABL2
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)11090-0.098-0.0363No
26STK10STK10
Entrez,  Source
serine/threonine kinase 1011218-0.103-0.0085No
27RIPK2RIPK2
Entrez,  Source
receptor-interacting serine-threonine kinase 211349-0.1100.0214No
28SLKSLK
Entrez,  Source
STE20-like kinase (yeast)11672-0.1280.0432No
29ABL1ABL1
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 112463-0.1970.0547No
Table: GSEA details [plain text format]



Fig 2: ERLOTINIB_KINOME SCAN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: ERLOTINIB_KINOME SCAN: Random ES distribution   
Gene set null distribution of ES for ERLOTINIB_KINOME SCAN