DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class1
GeneSetTG-100-115_KINOME SCAN
Enrichment Score (ES)0.3842972
Normalized Enrichment Score (NES)1.1308916
Nominal p-value0.2956989
FDR q-value0.71126235
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: TG-100-115_KINOME SCAN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1RIPK4RIPK4
Entrez,  Source
receptor-interacting serine-threonine kinase 4950.5440.1605Yes
2ERBB2ERBB2
Entrez,  Source
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)1000.5370.3259Yes
3EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)6250.2300.3570Yes
4PIK3C2GPIK3C2G
Entrez,  Source
phosphoinositide-3-kinase, class 2, gamma polypeptide14980.1230.3287Yes
5PIP4K2C16760.1140.3502Yes
6RPS6KA1RPS6KA1
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 116860.1130.3843Yes
7AAK1AAK1
Entrez,  Source
AP2 associated kinase 122120.0920.3727No
8TAOK1TAOK1
Entrez,  Source
TAO kinase 125520.0820.3722No
9MKNK1MKNK1
Entrez,  Source
MAP kinase interacting serine/threonine kinase 129070.0730.3677No
10CSNK1A1CSNK1A1
Entrez,  Source
casein kinase 1, alpha 136980.0580.3253No
11RPS6KA6RPS6KA6
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 646850.0420.2633No
12PIK3CGPIK3CG
Entrez,  Source
phosphoinositide-3-kinase, catalytic, gamma polypeptide53290.0330.2246No
13PIK3C2BPIK3C2B
Entrez,  Source
phosphoinositide-3-kinase, class 2, beta polypeptide54150.0320.2279No
14STK16STK16
Entrez,  Source
serine/threonine kinase 1657780.0270.2086No
15PIK3CBPIK3CB
Entrez,  Source
phosphoinositide-3-kinase, catalytic, beta polypeptide62250.0200.1810No
16PIP5K1CPIP5K1C
Entrez,  Source
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma68810.0100.1343No
17CLK4CLK4
Entrez,  Source
CDC-like kinase 469350.0100.1332No
18BMP2KBMP2K
Entrez,  Source
BMP2 inducible kinase70290.0080.1286No
19CLK2CLK2
Entrez,  Source
CDC-like kinase 271810.0050.1187No
20PI4KB7697-0.0030.0805No
21MKNK2MKNK2
Entrez,  Source
MAP kinase interacting serine/threonine kinase 27841-0.0060.0716No
22PIK3CDPIK3CD
Entrez,  Source
phosphoinositide-3-kinase, catalytic, delta polypeptide8176-0.0130.0501No
23DYRK1BDYRK1B
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B8200-0.0130.0524No
24PIK3CAPIK3CA
Entrez,  Source
phosphoinositide-3-kinase, catalytic, alpha polypeptide8749-0.0250.0184No
25TYK2TYK2
Entrez,  Source
tyrosine kinase 29438-0.041-0.0213No
26TRPM6TRPM6
Entrez,  Source
transient receptor potential cation channel, subfamily M, member 69502-0.043-0.0129No
27ADCK310237-0.064-0.0491No
28DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A10303-0.066-0.0337No
29JAK1JAK1
Entrez,  Source
Janus kinase 1 (a protein tyrosine kinase)10585-0.076-0.0318No
30MTOR10944-0.091-0.0309No
31RIPK2RIPK2
Entrez,  Source
receptor-interacting serine-threonine kinase 211349-0.110-0.0279No
32ABL1ABL1
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 112463-0.197-0.0517No
33PRKD3PRKD3
Entrez,  Source
protein kinase D313008-0.3450.0132No
Table: GSEA details [plain text format]



Fig 2: TG-100-115_KINOME SCAN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: TG-100-115_KINOME SCAN: Random ES distribution   
Gene set null distribution of ES for TG-100-115_KINOME SCAN