DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class0
GeneSetPHA-665752_KINOME SCAN
Enrichment Score (ES)-0.35465237
Normalized Enrichment Score (NES)-1.1952387
Nominal p-value0.18439716
FDR q-value0.82945096
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: PHA-665752_KINOME SCAN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1DDR1DDR1
Entrez,  Source
discoidin domain receptor family, member 12120.4040.0595No
2METMET
Entrez,  Source
met proto-oncogene (hepatocyte growth factor receptor)4990.2590.0862No
3TAOK3TAOK3
Entrez,  Source
TAO kinase 39710.1700.0821No
4TNIKTNIK
Entrez,  Source
TRAF2 and NCK interacting kinase11970.1450.0922No
5LCKLCK
Entrez,  Source
lymphocyte-specific protein tyrosine kinase13100.1360.1092No
6NTRK2NTRK2
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 217040.1120.1002No
7RIOK3RIOK3
Entrez,  Source
RIO kinase 3 (yeast)19420.1010.1011No
8PTK2BPTK2B
Entrez,  Source
PTK2B protein tyrosine kinase 2 beta20420.0980.1119No
9AAK1AAK1
Entrez,  Source
AP2 associated kinase 122120.0920.1163No
10JAK3JAK3
Entrez,  Source
Janus kinase 3 (a protein tyrosine kinase, leukocyte)24440.0840.1145No
11TAOK1TAOK1
Entrez,  Source
TAO kinase 125520.0820.1217No
12MAP4K1MAP4K1
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 128490.0740.1130No
13MINK1MINK1
Entrez,  Source
misshapen-like kinase 1 (zebrafish)30800.0690.1084No
14FLT3FLT3
Entrez,  Source
fms-related tyrosine kinase 334030.0630.0956No
15CSF1RCSF1R
Entrez,  Source
colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog34540.0620.1034No
16AURKCAURKC
Entrez,  Source
aurora kinase C44130.0460.0390No
17NEK2NEK2
Entrez,  Source
NIMA (never in mitosis gene a)-related kinase 244830.0450.0422No
18MAKMAK
Entrez,  Source
male germ cell-associated kinase51320.035-0.0005No
19NTRK1NTRK1
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 160970.022-0.0698No
20DCLK264620.016-0.0945No
21RETRET
Entrez,  Source
ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)64710.016-0.0920No
22GRK4GRK4
Entrez,  Source
G protein-coupled receptor kinase 467880.012-0.1139No
23BMP2KBMP2K
Entrez,  Source
BMP2 inducible kinase70290.008-0.1307No
24CLK2CLK2
Entrez,  Source
CDC-like kinase 271810.005-0.1412No
25IKBKEIKBKE
Entrez,  Source
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon72160.004-0.1430No
26PRKAA2PRKAA2
Entrez,  Source
protein kinase, AMP-activated, alpha 2 catalytic subunit74180.001-0.1581No
27CSNK1ECSNK1E
Entrez,  Source
casein kinase 1, epsilon7742-0.004-0.1819No
28KITKIT
Entrez,  Source
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog8134-0.012-0.2094No
29NTRK3NTRK3
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 38500-0.019-0.2336No
30HIPK3HIPK3
Entrez,  Source
homeodomain interacting protein kinase 39770-0.050-0.3210No
31MAP4K4MAP4K4
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 49922-0.055-0.3223No
32HIPK2HIPK2
Entrez,  Source
homeodomain interacting protein kinase 210151-0.061-0.3282No
33ICKICK
Entrez,  Source
intestinal cell (MAK-like) kinase10499-0.073-0.3411Yes
34PLK4PLK4
Entrez,  Source
polo-like kinase 4 (Drosophila)10581-0.075-0.3331Yes
35CAMKK2CAMKK2
Entrez,  Source
calcium/calmodulin-dependent protein kinase kinase 2, beta10729-0.081-0.3291Yes
36TBK1TBK1
Entrez,  Source
TANK-binding kinase 110732-0.082-0.3139Yes
37PIP5K1APIP5K1A
Entrez,  Source
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha10780-0.083-0.3019Yes
38CDK4CDK4
Entrez,  Source
cyclin-dependent kinase 410871-0.087-0.2924Yes
39PRKAA1PRKAA1
Entrez,  Source
protein kinase, AMP-activated, alpha 1 catalytic subunit10906-0.089-0.2783Yes
40NUAK1NUAK1
Entrez,  Source
NUAK family, SNF1-like kinase, 111032-0.095-0.2701Yes
41SRPK1SRPK1
Entrez,  Source
SFRS protein kinase 111068-0.096-0.2547Yes
42CDK7CDK7
Entrez,  Source
cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)11160-0.101-0.2428Yes
43STK10STK10
Entrez,  Source
serine/threonine kinase 1011218-0.103-0.2277Yes
44SRPK2SRPK2
Entrez,  Source
SFRS protein kinase 211496-0.117-0.2269Yes
45JAK2JAK2
Entrez,  Source
Janus kinase 2 (a protein tyrosine kinase)11530-0.119-0.2072Yes
46SLKSLK
Entrez,  Source
STE20-like kinase (yeast)11672-0.128-0.1940Yes
47MAP4K5MAP4K5
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 511705-0.130-0.1721Yes
48HIPK1HIPK1
Entrez,  Source
homeodomain interacting protein kinase 111798-0.135-0.1537Yes
49MAP2K2MAP2K2
Entrez,  Source
mitogen-activated protein kinase kinase 211895-0.142-0.1345Yes
50MAP3K12MAP3K12
Entrez,  Source
mitogen-activated protein kinase kinase kinase 1212384-0.186-0.1367Yes
51MAP4K3MAP4K3
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 312403-0.189-0.1027Yes
52IRAK3IRAK3
Entrez,  Source
interleukin-1 receptor-associated kinase 312451-0.196-0.0696Yes
53ABL1ABL1
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 112463-0.197-0.0335Yes
54CDK1712578-0.213-0.0022Yes
55AXLAXL
Entrez,  Source
AXL receptor tyrosine kinase12789-0.2570.0299Yes
Table: GSEA details [plain text format]



Fig 2: PHA-665752_KINOME SCAN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: PHA-665752_KINOME SCAN: Random ES distribution   
Gene set null distribution of ES for PHA-665752_KINOME SCAN