DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class0
GeneSetBIO (6-BROMOINDIRUBIN-3'-OXIME)_MRC
Enrichment Score (ES)-0.3537433
Normalized Enrichment Score (NES)-1.1071075
Nominal p-value0.29977116
FDR q-value0.8549932
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: BIO (6-BROMOINDIRUBIN-3'-OXIME)_MRC   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1MST43180.3310.0621No
2SYKSYK
Entrez,  Source
spleen tyrosine kinase4710.2680.1205No
3LCKLCK
Entrez,  Source
lymphocyte-specific protein tyrosine kinase13100.1360.0923No
4STK3STK3
Entrez,  Source
serine/threonine kinase 3 (STE20 homolog, yeast)15530.1200.1050No
5RPS6KA1RPS6KA1
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 116860.1130.1244No
6MAP3K11MAP3K11
Entrez,  Source
mitogen-activated protein kinase kinase kinase 1122950.0890.1014No
7RPS6KA5RPS6KA5
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 526100.0800.0984No
8PIM2PIM2
Entrez,  Source
pim-2 oncogene29560.0710.0908No
9YES1YES1
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 130360.0700.1030No
10EPHA2EPHA2
Entrez,  Source
EPH receptor A248800.039-0.0270No
11FLT1FLT1
Entrez,  Source
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)48820.039-0.0169No
12PAK4PAK4
Entrez,  Source
p21(CDKN1A)-activated kinase 450140.037-0.0172No
13BTKBTK
Entrez,  Source
Bruton agammaglobulinemia tyrosine kinase56280.029-0.0563No
14PAK7PAK7
Entrez,  Source
p21(CDKN1A)-activated kinase 758810.025-0.0688No
15NTRK1NTRK1
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 160970.022-0.0795No
16IKBKEIKBKE
Entrez,  Source
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon72160.004-0.1633No
17PRKAA2PRKAA2
Entrez,  Source
protein kinase, AMP-activated, alpha 2 catalytic subunit74180.001-0.1783No
18IGF1RIGF1R
Entrez,  Source
insulin-like growth factor 1 receptor7959-0.008-0.2172No
19MELKMELK
Entrez,  Source
maternal embryonic leucine zipper kinase8047-0.010-0.2213No
20PDK1PDK1
Entrez,  Source
pyruvate dehydrogenase kinase, isozyme 18449-0.018-0.2470No
21PHKA2PHKA2
Entrez,  Source
phosphorylase kinase, alpha 2 (liver)9057-0.032-0.2849No
22CDK2CDK2
Entrez,  Source
cyclin-dependent kinase 29409-0.040-0.3011No
23CHEK2CHEK2
Entrez,  Source
CHK2 checkpoint homolog (S. pombe)10102-0.059-0.3383Yes
24HIPK2HIPK2
Entrez,  Source
homeodomain interacting protein kinase 210151-0.061-0.3260Yes
25DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A10303-0.066-0.3203Yes
26MARK3MARK3
Entrez,  Source
MAP/microtubule affinity-regulating kinase 310374-0.068-0.3079Yes
27RPS6KB1RPS6KB1
Entrez,  Source
ribosomal protein S6 kinase, 70kDa, polypeptide 110717-0.081-0.3128Yes
28CAMKK2CAMKK2
Entrez,  Source
calcium/calmodulin-dependent protein kinase kinase 2, beta10729-0.081-0.2924Yes
29TBK1TBK1
Entrez,  Source
TANK-binding kinase 110732-0.082-0.2713Yes
30BRSK2BRSK2
Entrez,  Source
BR serine/threonine kinase 210749-0.082-0.2512Yes
31SRCSRC
Entrez,  Source
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)10776-0.083-0.2314Yes
32CHEK1CHEK1
Entrez,  Source
CHK1 checkpoint homolog (S. pombe)10792-0.084-0.2106Yes
33GSK3BGSK3B
Entrez,  Source
glycogen synthase kinase 3 beta11131-0.100-0.2103Yes
34MYLKMYLK
Entrez,  Source
myosin, light chain kinase11255-0.105-0.1923Yes
35ROCK2ROCK2
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 212033-0.152-0.2118Yes
36CAMK1CAMK1
Entrez,  Source
calcium/calmodulin-dependent protein kinase I12150-0.162-0.1783Yes
37FGFR1FGFR1
Entrez,  Source
fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)13121-0.486-0.1253Yes
38SGK113133-0.4980.0037Yes
Table: GSEA details [plain text format]



Fig 2: BIO (6-BROMOINDIRUBIN-3'-OXIME)_MRC   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: BIO (6-BROMOINDIRUBIN-3'-OXIME)_MRC: Random ES distribution   
Gene set null distribution of ES for BIO (6-BROMOINDIRUBIN-3'-OXIME)_MRC