DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class1
GeneSetCGP74514A_LINCS
Enrichment Score (ES)0.2869081
Normalized Enrichment Score (NES)1.0593398
Nominal p-value0.35148516
FDR q-value0.7839956
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: CGP74514A_LINCS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1DAPK1DAPK1
Entrez,  Source
death-associated protein kinase 1880.5570.0440Yes
2EPHA1EPHA1
Entrez,  Source
EPH receptor A1940.5450.0933Yes
3PAK6PAK6
Entrez,  Source
p21(CDKN1A)-activated kinase 61580.4590.1303Yes
4PRKCDPRKCD
Entrez,  Source
protein kinase C, delta3060.3370.1498Yes
5MST43180.3310.1791Yes
6PRKCHPRKCH
Entrez,  Source
protein kinase C, eta3560.3090.2044Yes
7RPS6KA2RPS6KA2
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 25900.2370.2082Yes
8EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)6250.2300.2265Yes
9CDK146590.2220.2442Yes
10CDK187600.2040.2551Yes
11TAOK3TAOK3
Entrez,  Source
TAO kinase 39710.1700.2546Yes
12TXKTXK
Entrez,  Source
TXK tyrosine kinase10450.1600.2635Yes
13LCKLCK
Entrez,  Source
lymphocyte-specific protein tyrosine kinase13100.1360.2557Yes
14SLC12A7SLC12A7
Entrez,  Source
solute carrier family 12 (potassium/chloride transporters), member 715430.1200.2489Yes
15STK17BSTK17B
Entrez,  Source
serine/threonine kinase 17b (apoptosis-inducing)15540.1190.2591Yes
16RPS6KA1RPS6KA1
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 116860.1130.2593Yes
17MAP3K9MAP3K9
Entrez,  Source
mitogen-activated protein kinase kinase kinase 916990.1120.2686Yes
18NTRK2NTRK2
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 217040.1120.2785Yes
19MAPK3MAPK3
Entrez,  Source
mitogen-activated protein kinase 317660.1090.2838Yes
20CSNK1DCSNK1D
Entrez,  Source
casein kinase 1, delta18510.1050.2869Yes
21ULK2ULK2
Entrez,  Source
unc-51-like kinase 2 (C. elegans)22440.0910.2652No
22MAP3K11MAP3K11
Entrez,  Source
mitogen-activated protein kinase kinase kinase 1122950.0890.2695No
23MERTKMERTK
Entrez,  Source
c-mer proto-oncogene tyrosine kinase25220.0820.2597No
24TAOK1TAOK1
Entrez,  Source
TAO kinase 125520.0820.2649No
25MAP4K1MAP4K1
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 128490.0740.2491No
26EPHA3EPHA3
Entrez,  Source
EPH receptor A328700.0740.2542No
27STK38STK38
Entrez,  Source
serine/threonine kinase 3828780.0730.2604No
28PIM2PIM2
Entrez,  Source
pim-2 oncogene29560.0710.2610No
29YES1YES1
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 130360.0700.2613No
30MINK1MINK1
Entrez,  Source
misshapen-like kinase 1 (zebrafish)30800.0690.2643No
31FLT3FLT3
Entrez,  Source
fms-related tyrosine kinase 334030.0630.2454No
32BLKBLK
Entrez,  Source
B lymphoid tyrosine kinase34190.0620.2499No
33CSNK1A1CSNK1A1
Entrez,  Source
casein kinase 1, alpha 136980.0580.2339No
34EPHB1EPHB1
Entrez,  Source
EPH receptor B140000.0520.2157No
35ALKALK
Entrez,  Source
anaplastic lymphoma kinase (Ki-1)40730.0510.2148No
36FGRFGR
Entrez,  Source
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog41930.0490.2102No
37AURKCAURKC
Entrez,  Source
aurora kinase C44130.0460.1976No
38RPS6KA6RPS6KA6
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 646850.0420.1807No
39GRK1GRK1
Entrez,  Source
G protein-coupled receptor kinase 149070.0390.1674No
40PAK4PAK4
Entrez,  Source
p21(CDKN1A)-activated kinase 450140.0370.1626No
41ULK1ULK1
Entrez,  Source
unc-51-like kinase 1 (C. elegans)51570.0350.1550No
42MAPK4MAPK4
Entrez,  Source
mitogen-activated protein kinase 455850.0290.1250No
43PAK7PAK7
Entrez,  Source
p21(CDKN1A)-activated kinase 758810.0250.1047No
44MAP3K3MAP3K3
Entrez,  Source
mitogen-activated protein kinase kinase kinase 359210.0250.1040No
45MAPK1MAPK1
Entrez,  Source
mitogen-activated protein kinase 159940.0240.1007No
46CDK1360620.0230.0976No
47NTRK1NTRK1
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 160970.0220.0970No
48IRAK1IRAK1
Entrez,  Source
interleukin-1 receptor-associated kinase 161790.0210.0927No
49PHKG1PHKG1
Entrez,  Source
phosphorylase kinase, gamma 1 (muscle)62450.0200.0895No
50CSNK1G2CSNK1G2
Entrez,  Source
casein kinase 1, gamma 263280.0180.0849No
51RETRET
Entrez,  Source
ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)64710.0160.0756No
52PKN1PKN1
Entrez,  Source
protein kinase N167830.0120.0529No
53PIP5K1CPIP5K1C
Entrez,  Source
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma68810.0100.0464No
54MAP4K2MAP4K2
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 268940.0100.0464No
55MAPK7MAPK7
Entrez,  Source
mitogen-activated protein kinase 769130.0100.0459No
56STK32BSTK32B
Entrez,  Source
serine/threonine kinase 32B69190.0100.0464No
57CLK4CLK4
Entrez,  Source
CDC-like kinase 469350.0100.0461No
58CLK2CLK2
Entrez,  Source
CDC-like kinase 271810.0050.0278No
59CDK5CDK5
Entrez,  Source
cyclin-dependent kinase 574320.0010.0088No
60CSNK1ECSNK1E
Entrez,  Source
casein kinase 1, epsilon7742-0.004-0.0144No
61PDGFRBPDGFRB
Entrez,  Source
platelet-derived growth factor receptor, beta polypeptide7824-0.006-0.0201No
62MATKMATK
Entrez,  Source
megakaryocyte-associated tyrosine kinase7989-0.009-0.0318No
63MELKMELK
Entrez,  Source
maternal embryonic leucine zipper kinase8047-0.010-0.0353No
64TAOK2TAOK2
Entrez,  Source
TAO kinase 28059-0.010-0.0352No
65KITKIT
Entrez,  Source
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog8134-0.012-0.0398No
66MAP2K5MAP2K5
Entrez,  Source
mitogen-activated protein kinase kinase 58199-0.013-0.0435No
67DYRK1BDYRK1B
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B8200-0.013-0.0423No
68CDK168353-0.016-0.0525No
69CDK3CDK3
Entrez,  Source
cyclin-dependent kinase 38440-0.018-0.0574No
70NTRK3NTRK3
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 38500-0.019-0.0601No
71CSNK1G1CSNK1G1
Entrez,  Source
casein kinase 1, gamma 18732-0.025-0.0756No
72ROCK1ROCK1
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 18741-0.025-0.0739No
73IRAK4IRAK4
Entrez,  Source
interleukin-1 receptor-associated kinase 48996-0.031-0.0906No
74CDK2CDK2
Entrez,  Source
cyclin-dependent kinase 29409-0.040-0.1184No
75TYK2TYK2
Entrez,  Source
tyrosine kinase 29438-0.041-0.1168No
76PAK3PAK3
Entrez,  Source
p21 (CDKN1A)-activated kinase 39490-0.042-0.1169No
77CSNK2A2CSNK2A2
Entrez,  Source
casein kinase 2, alpha prime polypeptide9758-0.049-0.1328No
78HIPK3HIPK3
Entrez,  Source
homeodomain interacting protein kinase 39770-0.050-0.1291No
79DCLK19840-0.052-0.1297No
80HCKHCK
Entrez,  Source
hemopoietic cell kinase9981-0.056-0.1353No
81STK17ASTK17A
Entrez,  Source
serine/threonine kinase 17a (apoptosis-inducing)10017-0.057-0.1327No
82HIPK2HIPK2
Entrez,  Source
homeodomain interacting protein kinase 210151-0.061-0.1374No
83DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A10303-0.066-0.1429No
84MARK3MARK3
Entrez,  Source
MAP/microtubule affinity-regulating kinase 310374-0.068-0.1421No
85RPS6KA3RPS6KA3
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 310427-0.070-0.1396No
86PLK1PLK1
Entrez,  Source
polo-like kinase 1 (Drosophila)10440-0.071-0.1341No
87ICKICK
Entrez,  Source
intestinal cell (MAK-like) kinase10499-0.073-0.1319No
88SRCSRC
Entrez,  Source
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)10776-0.083-0.1454No
89PAK2PAK2
Entrez,  Source
p21 (CDKN1A)-activated kinase 210809-0.085-0.1402No
90CDK4CDK4
Entrez,  Source
cyclin-dependent kinase 410871-0.087-0.1369No
91NUAK1NUAK1
Entrez,  Source
NUAK family, SNF1-like kinase, 111032-0.095-0.1405No
92DAPK3DAPK3
Entrez,  Source
death-associated protein kinase 311066-0.096-0.1342No
93CDK7CDK7
Entrez,  Source
cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)11160-0.101-0.1322No
94STK10STK10
Entrez,  Source
serine/threonine kinase 1011218-0.103-0.1271No
95JAK2JAK2
Entrez,  Source
Janus kinase 2 (a protein tyrosine kinase)11530-0.119-0.1401No
96CDK9CDK9
Entrez,  Source
cyclin-dependent kinase 9 (CDC2-related kinase)11631-0.125-0.1363No
97SLKSLK
Entrez,  Source
STE20-like kinase (yeast)11672-0.128-0.1277No
98FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES11767-0.133-0.1228No
99HIPK1HIPK1
Entrez,  Source
homeodomain interacting protein kinase 111798-0.135-0.1127No
100CSNK2A1CSNK2A1
Entrez,  Source
casein kinase 2, alpha 1 polypeptide11861-0.139-0.1048No
101ROCK2ROCK2
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 212033-0.152-0.1040No
102MAP3K2MAP3K2
Entrez,  Source
mitogen-activated protein kinase kinase kinase 212210-0.168-0.1022No
103MAPK6MAPK6
Entrez,  Source
mitogen-activated protein kinase 612214-0.168-0.0871No
104SIK112319-0.179-0.0787No
105ABL1ABL1
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 112463-0.197-0.0717No
106CSNK1G3CSNK1G3
Entrez,  Source
casein kinase 1, gamma 312464-0.197-0.0537No
107CDK1712578-0.213-0.0429No
108MAP3K7MAP3K7
Entrez,  Source
mitogen-activated protein kinase kinase kinase 712613-0.221-0.0254No
109AXLAXL
Entrez,  Source
AXL receptor tyrosine kinase12789-0.257-0.0154No
110SGK113133-0.4980.0037No
Table: GSEA details [plain text format]



Fig 2: CGP74514A_LINCS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: CGP74514A_LINCS: Random ES distribution   
Gene set null distribution of ES for CGP74514A_LINCS