DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class1
GeneSetAXITINIB_FDA
Enrichment Score (ES)0.35268998
Normalized Enrichment Score (NES)1.0468456
Nominal p-value0.37236086
FDR q-value0.7421966
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: AXITINIB_FDA   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1FGFR3FGFR3
Entrez,  Source
fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)1530.4650.0931Yes
2FGFR2FGFR2
Entrez,  Source
ffer syndrome, Jackson-Weiss syndrome)2100.4060.1801Yes
3DDR1DDR1
Entrez,  Source
discoidin domain receptor family, member 12120.4040.2708Yes
4METMET
Entrez,  Source
met proto-oncogene (hepatocyte growth factor receptor)4990.2590.3073Yes
5EPHB6EPHB6
Entrez,  Source
EPH receptor B67010.2150.3404Yes
6TNIKTNIK
Entrez,  Source
TRAF2 and NCK interacting kinase11970.1450.3355Yes
7TNK1TNK1
Entrez,  Source
tyrosine kinase, non-receptor, 113600.1310.3527Yes
8RIOK3RIOK3
Entrez,  Source
RIO kinase 3 (yeast)19420.1010.3313No
9TIE1TIE1
Entrez,  Source
tyrosine kinase with immunoglobulin-like and EGF-like domains 123280.0880.3217No
10MAP4K1MAP4K1
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 128490.0740.2989No
11MINK1MINK1
Entrez,  Source
misshapen-like kinase 1 (zebrafish)30800.0690.2969No
12KDRKDR
Entrez,  Source
kinase insert domain receptor (a type III receptor tyrosine kinase)31460.0680.3072No
13FLT3FLT3
Entrez,  Source
fms-related tyrosine kinase 334030.0630.3018No
14CSF1RCSF1R
Entrez,  Source
colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog34540.0620.3119No
15AURKCAURKC
Entrez,  Source
aurora kinase C44130.0460.2494No
16CDKL2CDKL2
Entrez,  Source
cyclin-dependent kinase-like 2 (CDC2-related kinase)45480.0440.2491No
17FLT1FLT1
Entrez,  Source
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)48820.0390.2325No
18FLT4FLT4
Entrez,  Source
fms-related tyrosine kinase 448980.0390.2402No
19STK16STK16
Entrez,  Source
serine/threonine kinase 1657780.0270.1793No
20AURKAAURKA
Entrez,  Source
aurora kinase A64270.0170.1339No
21RETRET
Entrez,  Source
ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)64710.0160.1343No
22BMP2KBMP2K
Entrez,  Source
BMP2 inducible kinase70290.0080.0937No
23TEKTEK
Entrez,  Source
TEK tyrosine kinase, endothelial (venous malformations, multiple cutaneous and mucosal)70350.0080.0951No
24PDGFRBPDGFRB
Entrez,  Source
platelet-derived growth factor receptor, beta polypeptide7824-0.0060.0365No
25KITKIT
Entrez,  Source
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog8134-0.0120.0156No
26MAP2K5MAP2K5
Entrez,  Source
mitogen-activated protein kinase kinase 58199-0.0130.0137No
27AURKBAURKB
Entrez,  Source
aurora kinase B8856-0.027-0.0300No
28MAP4K4MAP4K4
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 49922-0.055-0.0987No
29PLK4PLK4
Entrez,  Source
polo-like kinase 4 (Drosophila)10581-0.075-0.1318No
30ABL2ABL2
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)11090-0.098-0.1485No
31SLKSLK
Entrez,  Source
STE20-like kinase (yeast)11672-0.128-0.1640No
32MAP4K5MAP4K5
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 511705-0.130-0.1372No
33PDGFRAPDGFRA
Entrez,  Source
platelet-derived growth factor receptor, alpha polypeptide12211-0.168-0.1379No
34ABL1ABL1
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 112463-0.197-0.1126No
35AXLAXL
Entrez,  Source
AXL receptor tyrosine kinase12789-0.257-0.0795No
36FGFR1FGFR1
Entrez,  Source
fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)13121-0.4860.0046No
Table: GSEA details [plain text format]



Fig 2: AXITINIB_FDA   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: AXITINIB_FDA: Random ES distribution   
Gene set null distribution of ES for AXITINIB_FDA