DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class0
GeneSetGSK-690693_KINOME SCAN
Enrichment Score (ES)-0.28701413
Normalized Enrichment Score (NES)-0.9325891
Nominal p-value0.5707434
FDR q-value0.91259176
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: GSK-690693_KINOME SCAN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1PAK6PAK6
Entrez,  Source
p21(CDKN1A)-activated kinase 61580.4590.0990Yes
2PRKCDPRKCD
Entrez,  Source
protein kinase C, delta3060.3370.1692Yes
3PRKCHPRKCH
Entrez,  Source
protein kinase C, eta3560.3090.2402Yes
4PAK1PAK1
Entrez,  Source
p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)6740.2190.2690Yes
5TAOK1TAOK1
Entrez,  Source
TAO kinase 125520.0820.1459No
6RPS6KA5RPS6KA5
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 526100.0800.1610No
7PIM2PIM2
Entrez,  Source
pim-2 oncogene29560.0710.1520No
8MARK2MARK2
Entrez,  Source
MAP/microtubule affinity-regulating kinase 238340.0550.0985No
9PRKG2PRKG2
Entrez,  Source
protein kinase, cGMP-dependent, type II40210.0520.0969No
10PIM1PIM1
Entrez,  Source
pim-1 oncogene41360.0500.1004No
11GRK1GRK1
Entrez,  Source
G protein-coupled receptor kinase 149070.0390.0512No
12PRKG1PRKG1
Entrez,  Source
protein kinase, cGMP-dependent, type I49360.0380.0583No
13PAK4PAK4
Entrez,  Source
p21(CDKN1A)-activated kinase 450140.0370.0614No
14PAK7PAK7
Entrez,  Source
p21(CDKN1A)-activated kinase 758810.0250.0017No
15MAP3K3MAP3K3
Entrez,  Source
mitogen-activated protein kinase kinase kinase 359210.0250.0047No
16PRKXPRKX
Entrez,  Source
protein kinase, X-linked59930.0240.0051No
17CAMK4CAMK4
Entrez,  Source
calcium/calmodulin-dependent protein kinase IV63930.017-0.0211No
18PKN1PKN1
Entrez,  Source
protein kinase N167830.012-0.0478No
19CLK2CLK2
Entrez,  Source
CDC-like kinase 271810.005-0.0768No
20AKT1AKT1
Entrez,  Source
v-akt murine thymoma viral oncogene homolog 173870.002-0.0920No
21MELKMELK
Entrez,  Source
maternal embryonic leucine zipper kinase8047-0.010-0.1397No
22PRKACAPRKACA
Entrez,  Source
protein kinase, cAMP-dependent, catalytic, alpha8112-0.011-0.1419No
23KITKIT
Entrez,  Source
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog8134-0.012-0.1407No
24RPS6KA4RPS6KA4
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 48181-0.013-0.1411No
25PRKCIPRKCI
Entrez,  Source
protein kinase C, iota8226-0.014-0.1411No
26ROCK1ROCK1
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 18741-0.025-0.1742No
27HIPK3HIPK3
Entrez,  Source
homeodomain interacting protein kinase 39770-0.050-0.2404No
28HIPK2HIPK2
Entrez,  Source
homeodomain interacting protein kinase 210151-0.061-0.2546No
29CITCIT
Entrez,  Source
citron (rho-interacting, serine/threonine kinase 21)10420-0.070-0.2581No
30PRKCEPRKCE
Entrez,  Source
protein kinase C, epsilon10801-0.084-0.2666No
31PAK2PAK2
Entrez,  Source
p21 (CDKN1A)-activated kinase 210809-0.085-0.2467No
32PRKCQPRKCQ
Entrez,  Source
protein kinase C, theta10961-0.092-0.2360No
33NUAK1NUAK1
Entrez,  Source
NUAK family, SNF1-like kinase, 111032-0.095-0.2184No
34DAPK3DAPK3
Entrez,  Source
death-associated protein kinase 311066-0.096-0.1976No
35GSK3BGSK3B
Entrez,  Source
glycogen synthase kinase 3 beta11131-0.100-0.1784No
36PRKACBPRKACB
Entrez,  Source
protein kinase, cAMP-dependent, catalytic, beta11179-0.102-0.1573No
37HIPK1HIPK1
Entrez,  Source
homeodomain interacting protein kinase 111798-0.135-0.1716No
38ROCK2ROCK2
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 212033-0.152-0.1526No
39MAP3K2MAP3K2
Entrez,  Source
mitogen-activated protein kinase kinase kinase 212210-0.168-0.1255No
40AKT3AKT3
Entrez,  Source
v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)12533-0.207-0.0998No
41AKT2AKT2
Entrez,  Source
v-akt murine thymoma viral oncogene homolog 212829-0.271-0.0566No
42PRKD3PRKD3
Entrez,  Source
protein kinase D313008-0.3450.0132No
Table: GSEA details [plain text format]



Fig 2: GSK-690693_KINOME SCAN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: GSK-690693_KINOME SCAN: Random ES distribution   
Gene set null distribution of ES for GSK-690693_KINOME SCAN