DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class0
GeneSetQL-X-138_LINCS
Enrichment Score (ES)-0.29084703
Normalized Enrichment Score (NES)-0.94164
Nominal p-value0.5539906
FDR q-value0.9261001
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: QL-X-138_LINCS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)6250.2300.0289No
2TXKTXK
Entrez,  Source
TXK tyrosine kinase10450.1600.0501No
3MAPK10MAPK10
Entrez,  Source
mitogen-activated protein kinase 1010690.1570.1006No
4DYRK2DYRK2
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 212300.1420.1358No
5PIK3C2GPIK3C2G
Entrez,  Source
phosphoinositide-3-kinase, class 2, gamma polypeptide14980.1230.1565No
6PIP4K2C16760.1140.1807No
7JAK3JAK3
Entrez,  Source
Janus kinase 3 (a protein tyrosine kinase, leukocyte)24440.0840.1504No
8FLT3FLT3
Entrez,  Source
fms-related tyrosine kinase 334030.0630.0983No
9BLKBLK
Entrez,  Source
B lymphoid tyrosine kinase34190.0620.1179No
10CDKL5CDKL5
Entrez,  Source
cyclin-dependent kinase-like 543450.0470.0631No
11BMXBMX
Entrez,  Source
BMX non-receptor tyrosine kinase48260.0400.0399No
12PIK3CGPIK3CG
Entrez,  Source
phosphoinositide-3-kinase, catalytic, gamma polypeptide53290.0330.0126No
13TECTEC
Entrez,  Source
tec protein tyrosine kinase53790.0320.0196No
14BTKBTK
Entrez,  Source
Bruton agammaglobulinemia tyrosine kinase56280.0290.0103No
15BMPR1BBMPR1B
Entrez,  Source
bone morphogenetic protein receptor, type IB67770.012-0.0731No
16MAPK8MAPK8
Entrez,  Source
mitogen-activated protein kinase 868290.011-0.0733No
17MAP4K2MAP4K2
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 268940.010-0.0748No
18CLK4CLK4
Entrez,  Source
CDC-like kinase 469350.010-0.0747No
19CLK2CLK2
Entrez,  Source
CDC-like kinase 271810.005-0.0916No
20GSK3AGSK3A
Entrez,  Source
glycogen synthase kinase 3 alpha73580.002-0.1043No
21PI4KB7697-0.003-0.1290No
22MAP2K3MAP2K3
Entrez,  Source
mitogen-activated protein kinase kinase 37798-0.005-0.1348No
23PDGFRBPDGFRB
Entrez,  Source
platelet-derived growth factor receptor, beta polypeptide7824-0.006-0.1347No
24MAPK9MAPK9
Entrez,  Source
mitogen-activated protein kinase 97830-0.006-0.1331No
25MKNK2MKNK2
Entrez,  Source
MAP kinase interacting serine/threonine kinase 27841-0.006-0.1318No
26KITKIT
Entrez,  Source
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog8134-0.012-0.1501No
27MAP2K5MAP2K5
Entrez,  Source
mitogen-activated protein kinase kinase 58199-0.013-0.1506No
28DYRK1BDYRK1B
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B8200-0.013-0.1462No
29PIK3CAPIK3CA
Entrez,  Source
phosphoinositide-3-kinase, catalytic, alpha polypeptide8749-0.025-0.1796No
30CSNK2A2CSNK2A2
Entrez,  Source
casein kinase 2, alpha prime polypeptide9758-0.049-0.2399No
31MAP2K7MAP2K7
Entrez,  Source
mitogen-activated protein kinase kinase 79831-0.052-0.2282No
32DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A10303-0.066-0.2421No
33MTOR10944-0.091-0.2606Yes
34NUAK1NUAK1
Entrez,  Source
NUAK family, SNF1-like kinase, 111032-0.095-0.2357Yes
35CDK7CDK7
Entrez,  Source
cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)11160-0.101-0.2119Yes
36MAP2K4MAP2K4
Entrez,  Source
mitogen-activated protein kinase kinase 411811-0.136-0.2161Yes
37CSNK2A1CSNK2A1
Entrez,  Source
casein kinase 2, alpha 1 polypeptide11861-0.139-0.1735Yes
38IRAK3IRAK3
Entrez,  Source
interleukin-1 receptor-associated kinase 312451-0.196-0.1532Yes
39RIOK2RIOK2
Entrez,  Source
RIO kinase 2 (yeast)12467-0.198-0.0886Yes
40ZAKZAK
Entrez,  Source
-12544-0.209-0.0249Yes
41MAP3K7MAP3K7
Entrez,  Source
mitogen-activated protein kinase kinase kinase 712613-0.2210.0433Yes
Table: GSEA details [plain text format]



Fig 2: QL-X-138_LINCS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: QL-X-138_LINCS: Random ES distribution   
Gene set null distribution of ES for QL-X-138_LINCS