DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class1
GeneSetZM-447439_LINCS
Enrichment Score (ES)0.50220335
Normalized Enrichment Score (NES)1.5458826
Nominal p-value0.028520498
FDR q-value1.0
FWER p-Value0.957
Table: GSEA Results Summary



Fig 1: Enrichment plot: ZM-447439_LINCS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1ERBB3ERBB3
Entrez,  Source
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)121.0340.1684Yes
2MST1RMST1R
Entrez,  Source
macrophage stimulating 1 receptor (c-met-related tyrosine kinase)540.6360.2695Yes
3ERBB2ERBB2
Entrez,  Source
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)1000.5370.3540Yes
4PTK6PTK6
Entrez,  Source
PTK6 protein tyrosine kinase 61410.4790.4293Yes
5METMET
Entrez,  Source
met proto-oncogene (hepatocyte growth factor receptor)4990.2590.4445Yes
6EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)6250.2300.4727Yes
7EPHB6EPHB6
Entrez,  Source
EPH receptor B67010.2150.5022Yes
8LCKLCK
Entrez,  Source
lymphocyte-specific protein tyrosine kinase13100.1360.4782No
9PIK3C2GPIK3C2G
Entrez,  Source
phosphoinositide-3-kinase, class 2, gamma polypeptide14980.1230.4842No
10ERBB4ERBB4
Entrez,  Source
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)18130.1070.4777No
11LYNLYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog19740.1000.4818No
12MERTKMERTK
Entrez,  Source
c-mer proto-oncogene tyrosine kinase25220.0820.4537No
13TNK2TNK2
Entrez,  Source
tyrosine kinase, non-receptor, 230050.0700.4286No
14CSKCSK
Entrez,  Source
c-src tyrosine kinase30690.0690.4351No
15FLT3FLT3
Entrez,  Source
fms-related tyrosine kinase 334030.0630.4200No
16BLKBLK
Entrez,  Source
B lymphoid tyrosine kinase34190.0620.4290No
17CDKL2CDKL2
Entrez,  Source
cyclin-dependent kinase-like 2 (CDC2-related kinase)45480.0440.3504No
18BTKBTK
Entrez,  Source
Bruton agammaglobulinemia tyrosine kinase56280.0290.2730No
19AURKAAURKA
Entrez,  Source
aurora kinase A64270.0170.2151No
20RETRET
Entrez,  Source
ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)64710.0160.2145No
21PDGFRBPDGFRB
Entrez,  Source
platelet-derived growth factor receptor, beta polypeptide7824-0.0060.1126No
22MKNK2MKNK2
Entrez,  Source
MAP kinase interacting serine/threonine kinase 27841-0.0060.1124No
23MAP2K1MAP2K1
Entrez,  Source
mitogen-activated protein kinase kinase 17939-0.0080.1063No
24KITKIT
Entrez,  Source
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog8134-0.0120.0935No
25LTKLTK
Entrez,  Source
leukocyte tyrosine kinase8158-0.0120.0937No
26MAP2K5MAP2K5
Entrez,  Source
mitogen-activated protein kinase kinase 58199-0.0130.0929No
27AURKBAURKB
Entrez,  Source
aurora kinase B8856-0.0270.0474No
28CDK11A9060-0.0320.0372No
29HCKHCK
Entrez,  Source
hemopoietic cell kinase9981-0.056-0.0236No
30PLK4PLK4
Entrez,  Source
polo-like kinase 4 (Drosophila)10581-0.075-0.0568No
31RPS6KB1RPS6KB1
Entrez,  Source
ribosomal protein S6 kinase, 70kDa, polypeptide 110717-0.081-0.0539No
32CDK7CDK7
Entrez,  Source
cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)11160-0.101-0.0710No
33STK10STK10
Entrez,  Source
serine/threonine kinase 1011218-0.103-0.0584No
34RIPK2RIPK2
Entrez,  Source
receptor-interacting serine-threonine kinase 211349-0.110-0.0504No
35SLKSLK
Entrez,  Source
STE20-like kinase (yeast)11672-0.128-0.0540No
36MAP4K5MAP4K5
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 511705-0.130-0.0352No
37HIPK1HIPK1
Entrez,  Source
homeodomain interacting protein kinase 111798-0.135-0.0200No
38MAP2K2MAP2K2
Entrez,  Source
mitogen-activated protein kinase kinase 211895-0.142-0.0041No
39PDGFRAPDGFRA
Entrez,  Source
platelet-derived growth factor receptor, alpha polypeptide12211-0.168-0.0006No
40ABL1ABL1
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 112463-0.1970.0126No
41AXLAXL
Entrez,  Source
AXL receptor tyrosine kinase12789-0.2570.0299No
Table: GSEA details [plain text format]



Fig 2: ZM-447439_LINCS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: ZM-447439_LINCS: Random ES distribution   
Gene set null distribution of ES for ZM-447439_LINCS