DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class1
GeneSetCI-1033_KINOME SCAN
Enrichment Score (ES)0.6282365
Normalized Enrichment Score (NES)1.7771891
Nominal p-value0.0
FDR q-value0.4144198
FWER p-Value0.288
Table: GSEA Results Summary



Fig 1: Enrichment plot: CI-1033_KINOME SCAN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1ERBB3ERBB3
Entrez,  Source
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)121.0340.2418Yes
2ERBB2ERBB2
Entrez,  Source
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)1000.5370.3612Yes
3DDR1DDR1
Entrez,  Source
discoidin domain receptor family, member 12120.4040.4475Yes
4METMET
Entrez,  Source
met proto-oncogene (hepatocyte growth factor receptor)4990.2590.4864Yes
5EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)6250.2300.5309Yes
6EPHB6EPHB6
Entrez,  Source
EPH receptor B67010.2150.5757Yes
7TXKTXK
Entrez,  Source
TXK tyrosine kinase10450.1600.5871Yes
8LCKLCK
Entrez,  Source
lymphocyte-specific protein tyrosine kinase13100.1360.5989Yes
9GAKGAK
Entrez,  Source
cyclin G associated kinase13400.1330.6279Yes
10ERBB4ERBB4
Entrez,  Source
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)18130.1070.6170Yes
11LYNLYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog19740.1000.6282Yes
12JAK3JAK3
Entrez,  Source
Janus kinase 3 (a protein tyrosine kinase, leukocyte)24440.0840.6124No
13MKNK1MKNK1
Entrez,  Source
MAP kinase interacting serine/threonine kinase 129070.0730.5943No
14FLT3FLT3
Entrez,  Source
fms-related tyrosine kinase 334030.0630.5714No
15BLKBLK
Entrez,  Source
B lymphoid tyrosine kinase34190.0620.5849No
16IRAK1IRAK1
Entrez,  Source
interleukin-1 receptor-associated kinase 161790.0210.3800No
17RETRET
Entrez,  Source
ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)64710.0160.3617No
18MAP4K2MAP4K2
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 268940.0100.3320No
19TGFBR2TGFBR2
Entrez,  Source
transforming growth factor, beta receptor II (70/80kDa)71030.0070.3178No
20SIK37726-0.0040.2714No
21CSNK1ECSNK1E
Entrez,  Source
casein kinase 1, epsilon7742-0.0040.2713No
22KITKIT
Entrez,  Source
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog8134-0.0120.2443No
23MAP2K5MAP2K5
Entrez,  Source
mitogen-activated protein kinase kinase 58199-0.0130.2425No
24MAP2K7MAP2K7
Entrez,  Source
mitogen-activated protein kinase kinase 79831-0.0520.1307No
25ABL2ABL2
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)11090-0.0980.0579No
26RIPK2RIPK2
Entrez,  Source
receptor-interacting serine-threonine kinase 211349-0.1100.0640No
27TYRO3TYRO3
Entrez,  Source
TYRO3 protein tyrosine kinase11601-0.1230.0739No
28ABL1ABL1
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 112463-0.1970.0547No
Table: GSEA details [plain text format]



Fig 2: CI-1033_KINOME SCAN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: CI-1033_KINOME SCAN: Random ES distribution   
Gene set null distribution of ES for CI-1033_KINOME SCAN