| Dataset | NSCLC_collapsed_to_symbols.NSCLC.cls #SEN_versus_RES.NSCLC.cls #SEN_versus_RES_repos |
| Phenotype | NSCLC.cls#SEN_versus_RES_repos |
| Upregulated in class | 1 |
| GeneSet | TG-100-115_KINOME SCAN |
| Enrichment Score (ES) | 0.3842972 |
| Normalized Enrichment Score (NES) | 1.1308916 |
| Nominal p-value | 0.2956989 |
| FDR q-value | 0.71126235 |
| FWER p-Value | 1.0 |

| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RIPK4 | RIPK4 Entrez,  Source | receptor-interacting serine-threonine kinase 4 | 95 | 0.544 | 0.1605 | Yes |
| 2 | ERBB2 | ERBB2 Entrez,  Source | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 100 | 0.537 | 0.3259 | Yes |
| 3 | EGFR | EGFR Entrez,  Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 625 | 0.230 | 0.3570 | Yes |
| 4 | PIK3C2G | PIK3C2G Entrez,  Source | phosphoinositide-3-kinase, class 2, gamma polypeptide | 1498 | 0.123 | 0.3287 | Yes |
| 5 | PIP4K2C | 1676 | 0.114 | 0.3502 | Yes | ||
| 6 | RPS6KA1 | RPS6KA1 Entrez,  Source | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 1686 | 0.113 | 0.3843 | Yes |
| 7 | AAK1 | AAK1 Entrez,  Source | AP2 associated kinase 1 | 2212 | 0.092 | 0.3727 | No |
| 8 | TAOK1 | TAOK1 Entrez,  Source | TAO kinase 1 | 2552 | 0.082 | 0.3722 | No |
| 9 | MKNK1 | MKNK1 Entrez,  Source | MAP kinase interacting serine/threonine kinase 1 | 2907 | 0.073 | 0.3677 | No |
| 10 | CSNK1A1 | CSNK1A1 Entrez,  Source | casein kinase 1, alpha 1 | 3698 | 0.058 | 0.3253 | No |
| 11 | RPS6KA6 | RPS6KA6 Entrez,  Source | ribosomal protein S6 kinase, 90kDa, polypeptide 6 | 4685 | 0.042 | 0.2633 | No |
| 12 | PIK3CG | PIK3CG Entrez,  Source | phosphoinositide-3-kinase, catalytic, gamma polypeptide | 5329 | 0.033 | 0.2246 | No |
| 13 | PIK3C2B | PIK3C2B Entrez,  Source | phosphoinositide-3-kinase, class 2, beta polypeptide | 5415 | 0.032 | 0.2279 | No |
| 14 | STK16 | STK16 Entrez,  Source | serine/threonine kinase 16 | 5778 | 0.027 | 0.2086 | No |
| 15 | PIK3CB | PIK3CB Entrez,  Source | phosphoinositide-3-kinase, catalytic, beta polypeptide | 6225 | 0.020 | 0.1810 | No |
| 16 | PIP5K1C | PIP5K1C Entrez,  Source | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma | 6881 | 0.010 | 0.1343 | No |
| 17 | CLK4 | CLK4 Entrez,  Source | CDC-like kinase 4 | 6935 | 0.010 | 0.1332 | No |
| 18 | BMP2K | BMP2K Entrez,  Source | BMP2 inducible kinase | 7029 | 0.008 | 0.1286 | No |
| 19 | CLK2 | CLK2 Entrez,  Source | CDC-like kinase 2 | 7181 | 0.005 | 0.1187 | No |
| 20 | PI4KB | 7697 | -0.003 | 0.0805 | No | ||
| 21 | MKNK2 | MKNK2 Entrez,  Source | MAP kinase interacting serine/threonine kinase 2 | 7841 | -0.006 | 0.0716 | No |
| 22 | PIK3CD | PIK3CD Entrez,  Source | phosphoinositide-3-kinase, catalytic, delta polypeptide | 8176 | -0.013 | 0.0501 | No |
| 23 | DYRK1B | DYRK1B Entrez,  Source | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B | 8200 | -0.013 | 0.0524 | No |
| 24 | PIK3CA | PIK3CA Entrez,  Source | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 8749 | -0.025 | 0.0184 | No |
| 25 | TYK2 | TYK2 Entrez,  Source | tyrosine kinase 2 | 9438 | -0.041 | -0.0213 | No |
| 26 | TRPM6 | TRPM6 Entrez,  Source | transient receptor potential cation channel, subfamily M, member 6 | 9502 | -0.043 | -0.0129 | No |
| 27 | ADCK3 | 10237 | -0.064 | -0.0491 | No | ||
| 28 | DYRK1A | DYRK1A Entrez,  Source | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 10303 | -0.066 | -0.0337 | No |
| 29 | JAK1 | JAK1 Entrez,  Source | Janus kinase 1 (a protein tyrosine kinase) | 10585 | -0.076 | -0.0318 | No |
| 30 | MTOR | 10944 | -0.091 | -0.0309 | No | ||
| 31 | RIPK2 | RIPK2 Entrez,  Source | receptor-interacting serine-threonine kinase 2 | 11349 | -0.110 | -0.0279 | No |
| 32 | ABL1 | ABL1 Entrez,  Source | v-abl Abelson murine leukemia viral oncogene homolog 1 | 12463 | -0.197 | -0.0517 | No |
| 33 | PRKD3 | PRKD3 Entrez,  Source | protein kinase D3 | 13008 | -0.345 | 0.0132 | No |

