DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class1
GeneSetKINOME_1194_ROCHE
Enrichment Score (ES)0.3988801
Normalized Enrichment Score (NES)1.1924044
Nominal p-value0.22321428
FDR q-value0.64772755
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: KINOME_1194_ROCHE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1MST1RMST1R
Entrez,  Source
macrophage stimulating 1 receptor (c-met-related tyrosine kinase)540.6360.1592Yes
2FGFR3FGFR3
Entrez,  Source
fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)1530.4650.2712Yes
3FRKFRK
Entrez,  Source
fyn-related kinase2960.3430.3486Yes
4ROS1ROS1
Entrez,  Source
v-ros UR2 sarcoma virus oncogene homolog 1 (avian)5050.2580.3989Yes
5STK3STK3
Entrez,  Source
serine/threonine kinase 3 (STE20 homolog, yeast)15530.1200.3499No
6JAK3JAK3
Entrez,  Source
Janus kinase 3 (a protein tyrosine kinase, leukocyte)24440.0840.3039No
7TNK2TNK2
Entrez,  Source
tyrosine kinase, non-receptor, 230050.0700.2794No
8BLKBLK
Entrez,  Source
B lymphoid tyrosine kinase34190.0620.2640No
9ALKALK
Entrez,  Source
anaplastic lymphoma kinase (Ki-1)40730.0510.2274No
10EPHA2EPHA2
Entrez,  Source
EPH receptor A248800.0390.1762No
11PAK4PAK4
Entrez,  Source
p21(CDKN1A)-activated kinase 450140.0370.1756No
12PDPK1PDPK1
Entrez,  Source
3-phosphoinositide dependent protein kinase-155490.0300.1427No
13MAPK1MAPK1
Entrez,  Source
mitogen-activated protein kinase 159940.0240.1150No
14AURKAAURKA
Entrez,  Source
aurora kinase A64270.0170.0865No
15RETRET
Entrez,  Source
ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)64710.0160.0874No
16MAP3K10MAP3K10
Entrez,  Source
mitogen-activated protein kinase kinase kinase 1065490.0150.0855No
17MAP4K2MAP4K2
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 268940.0100.0619No
18ITKITK
Entrez,  Source
IL2-inducible T-cell kinase72200.0040.0383No
19SIK274350.0010.0223No
20IGF1RIGF1R
Entrez,  Source
insulin-like growth factor 1 receptor7959-0.008-0.0153No
21LTKLTK
Entrez,  Source
leukocyte tyrosine kinase8158-0.012-0.0273No
22MARK4MARK4
Entrez,  Source
MAP/microtubule affinity-regulating kinase 48259-0.014-0.0312No
23PTK2PTK2
Entrez,  Source
PTK2 protein tyrosine kinase 28356-0.016-0.0343No
24ROCK1ROCK1
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 18741-0.025-0.0572No
25IRAK4IRAK4
Entrez,  Source
interleukin-1 receptor-associated kinase 48996-0.031-0.0686No
26TYK2TYK2
Entrez,  Source
tyrosine kinase 29438-0.041-0.0917No
27MARK3MARK3
Entrez,  Source
MAP/microtubule affinity-regulating kinase 310374-0.068-0.1453No
28RPS6KA3RPS6KA3
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 310427-0.070-0.1312No
29PLK4PLK4
Entrez,  Source
polo-like kinase 4 (Drosophila)10581-0.075-0.1235No
30CAMKK2CAMKK2
Entrez,  Source
calcium/calmodulin-dependent protein kinase kinase 2, beta10729-0.081-0.1138No
31PRKAA1PRKAA1
Entrez,  Source
protein kinase, AMP-activated, alpha 1 catalytic subunit10906-0.089-0.1044No
32JAK2JAK2
Entrez,  Source
Janus kinase 2 (a protein tyrosine kinase)11530-0.119-0.1212No
33ABL1ABL1
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 112463-0.197-0.1415No
34CDC7CDC7
Entrez,  Source
CDC7 cell division cycle 7 (S. cerevisiae)12853-0.278-0.0998No
35FGFR1FGFR1
Entrez,  Source
fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)13121-0.4860.0046No
Table: GSEA details [plain text format]



Fig 2: KINOME_1194_ROCHE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: KINOME_1194_ROCHE: Random ES distribution   
Gene set null distribution of ES for KINOME_1194_ROCHE