DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class0
GeneSetSYK INHIBITOR I_MRC
Enrichment Score (ES)-0.26653367
Normalized Enrichment Score (NES)-0.83826584
Nominal p-value0.74040633
FDR q-value0.95417327
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: SYK INHIBITOR I_MRC   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1PAK6PAK6
Entrez,  Source
p21(CDKN1A)-activated kinase 61580.4590.1207No
2MST43180.3310.2043No
3LCKLCK
Entrez,  Source
lymphocyte-specific protein tyrosine kinase13100.1360.1682No
4STK3STK3
Entrez,  Source
serine/threonine kinase 3 (STE20 homolog, yeast)15530.1200.1843No
5INSRINSR
Entrez,  Source
insulin receptor16640.1140.2090No
6RPS6KA1RPS6KA1
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 116860.1130.2400No
7MAP3K11MAP3K11
Entrez,  Source
mitogen-activated protein kinase kinase kinase 1122950.0890.2195No
8YES1YES1
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 130360.0700.1834No
9NEK2NEK2
Entrez,  Source
NIMA (never in mitosis gene a)-related kinase 244830.0450.0864No
10FLT1FLT1
Entrez,  Source
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)48820.0390.0674No
11PAK4PAK4
Entrez,  Source
p21(CDKN1A)-activated kinase 450140.0370.0682No
12BTKBTK
Entrez,  Source
Bruton agammaglobulinemia tyrosine kinase56280.0290.0299No
13PAK7PAK7
Entrez,  Source
p21(CDKN1A)-activated kinase 758810.0250.0181No
14NTRK1NTRK1
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 160970.0220.0081No
15AURKAAURKA
Entrez,  Source
aurora kinase A64270.017-0.0120No
16MAP4K2MAP4K2
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 268940.010-0.0446No
17CLK2CLK2
Entrez,  Source
CDC-like kinase 271810.005-0.0648No
18IKBKEIKBKE
Entrez,  Source
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon72160.004-0.0661No
19PRKAA2PRKAA2
Entrez,  Source
protein kinase, AMP-activated, alpha 2 catalytic subunit74180.001-0.0811No
20MAP2K1MAP2K1
Entrez,  Source
mitogen-activated protein kinase kinase 17939-0.008-0.1183No
21AURKBAURKB
Entrez,  Source
aurora kinase B8856-0.027-0.1800No
22IRAK4IRAK4
Entrez,  Source
interleukin-1 receptor-associated kinase 48996-0.031-0.1818No
23PHKA2PHKA2
Entrez,  Source
phosphorylase kinase, alpha 2 (liver)9057-0.032-0.1771No
24CHEK2CHEK2
Entrez,  Source
CHK2 checkpoint homolog (S. pombe)10102-0.059-0.2394No
25RPS6KA3RPS6KA3
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 310427-0.070-0.2436Yes
26CAMKK2CAMKK2
Entrez,  Source
calcium/calmodulin-dependent protein kinase kinase 2, beta10729-0.081-0.2430Yes
27TBK1TBK1
Entrez,  Source
TANK-binding kinase 110732-0.082-0.2196Yes
28BRSK2BRSK2
Entrez,  Source
BR serine/threonine kinase 210749-0.082-0.1971Yes
29SRCSRC
Entrez,  Source
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)10776-0.083-0.1750Yes
30CHEK1CHEK1
Entrez,  Source
CHK1 checkpoint homolog (S. pombe)10792-0.084-0.1519Yes
31JAK2JAK2
Entrez,  Source
Janus kinase 2 (a protein tyrosine kinase)11530-0.119-0.1736Yes
32ROCK2ROCK2
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 212033-0.152-0.1678Yes
33PKN2PKN2
Entrez,  Source
protein kinase N212286-0.175-0.1363Yes
34MAP3K7MAP3K7
Entrez,  Source
mitogen-activated protein kinase kinase kinase 712613-0.221-0.0973Yes
35FGFR1FGFR1
Entrez,  Source
fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)13121-0.4860.0046Yes
Table: GSEA details [plain text format]



Fig 2: SYK INHIBITOR I_MRC   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: SYK INHIBITOR I_MRC: Random ES distribution   
Gene set null distribution of ES for SYK INHIBITOR I_MRC