DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class0
GeneSetMOMELOTINIB_LINCS
Enrichment Score (ES)-0.3107698
Normalized Enrichment Score (NES)-1.0674077
Nominal p-value0.34265736
FDR q-value0.8449351
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: MOMELOTINIB_LINCS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1DAPK1DAPK1
Entrez,  Source
death-associated protein kinase 1880.5570.1085No
2IKBKBIKBKB
Entrez,  Source
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta5530.2450.1238No
3MAPK10MAPK10
Entrez,  Source
mitogen-activated protein kinase 1010690.1570.1171No
4GAKGAK
Entrez,  Source
cyclin G associated kinase13400.1330.1241No
5STK17BSTK17B
Entrez,  Source
serine/threonine kinase 17b (apoptosis-inducing)15540.1190.1326No
6RIOK3RIOK3
Entrez,  Source
RIO kinase 3 (yeast)19420.1010.1241No
7AAK1AAK1
Entrez,  Source
AP2 associated kinase 122120.0920.1226No
8JAK3JAK3
Entrez,  Source
Janus kinase 3 (a protein tyrosine kinase, leukocyte)24440.0840.1225No
9RPS6KA5RPS6KA5
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 526100.0800.1265No
10MAP4K1MAP4K1
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 128490.0740.1237No
11FLT3FLT3
Entrez,  Source
fms-related tyrosine kinase 334030.0630.0945No
12CAMK2BCAMK2B
Entrez,  Source
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta42130.0490.0430No
13NEK7NEK7
Entrez,  Source
NIMA (never in mitosis gene a)-related kinase 748770.0390.0006No
14ACVR1ACVR1
Entrez,  Source
activin A receptor, type I52300.034-0.0191No
15PIK3CGPIK3CG
Entrez,  Source
phosphoinositide-3-kinase, catalytic, gamma polypeptide53290.033-0.0198No
16STK16STK16
Entrez,  Source
serine/threonine kinase 1657780.027-0.0484No
17IRAK1IRAK1
Entrez,  Source
interleukin-1 receptor-associated kinase 161790.021-0.0745No
18AURKAAURKA
Entrez,  Source
aurora kinase A64270.017-0.0898No
19PLK3PLK3
Entrez,  Source
polo-like kinase 3 (Drosophila)67550.012-0.1122No
20BMPR1BBMPR1B
Entrez,  Source
bone morphogenetic protein receptor, type IB67770.012-0.1113No
21GRK4GRK4
Entrez,  Source
G protein-coupled receptor kinase 467880.012-0.1096No
22MAPK8MAPK8
Entrez,  Source
mitogen-activated protein kinase 868290.011-0.1104No
23CLK4CLK4
Entrez,  Source
CDC-like kinase 469350.010-0.1164No
24BMP2KBMP2K
Entrez,  Source
BMP2 inducible kinase70290.008-0.1218No
25CLK2CLK2
Entrez,  Source
CDC-like kinase 271810.005-0.1322No
26IKBKEIKBKE
Entrez,  Source
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon72160.004-0.1339No
27SIK274350.001-0.1503No
28PDGFRBPDGFRB
Entrez,  Source
platelet-derived growth factor receptor, beta polypeptide7824-0.006-0.1786No
29MKNK2MKNK2
Entrez,  Source
MAP kinase interacting serine/threonine kinase 27841-0.006-0.1786No
30ROCK1ROCK1
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 18741-0.025-0.2419No
31TYK2TYK2
Entrez,  Source
tyrosine kinase 29438-0.041-0.2865No
32CSNK2A2CSNK2A2
Entrez,  Source
casein kinase 2, alpha prime polypeptide9758-0.049-0.3006Yes
33NEK9NEK9
Entrez,  Source
NIMA (never in mitosis gene a)- related kinase 99810-0.051-0.2940Yes
34STK17ASTK17A
Entrez,  Source
serine/threonine kinase 17a (apoptosis-inducing)10017-0.057-0.2979Yes
35HIPK2HIPK2
Entrez,  Source
homeodomain interacting protein kinase 210151-0.061-0.2954Yes
36BUB1BUB1
Entrez,  Source
BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast)10160-0.061-0.2833Yes
37CITCIT
Entrez,  Source
citron (rho-interacting, serine/threonine kinase 21)10420-0.070-0.2886Yes
38PLK4PLK4
Entrez,  Source
polo-like kinase 4 (Drosophila)10581-0.075-0.2852Yes
39JAK1JAK1
Entrez,  Source
Janus kinase 1 (a protein tyrosine kinase)10585-0.076-0.2698Yes
40TBK1TBK1
Entrez,  Source
TANK-binding kinase 110732-0.082-0.2640Yes
41CDK4CDK4
Entrez,  Source
cyclin-dependent kinase 410871-0.087-0.2565Yes
42MAPKAPK5MAPKAPK5
Entrez,  Source
mitogen-activated protein kinase-activated protein kinase 510962-0.092-0.2443Yes
43DAPK3DAPK3
Entrez,  Source
death-associated protein kinase 311066-0.096-0.2323Yes
44SRPK1SRPK1
Entrez,  Source
SFRS protein kinase 111068-0.096-0.2124Yes
45CDK7CDK7
Entrez,  Source
cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)11160-0.101-0.1985Yes
46JAK2JAK2
Entrez,  Source
Janus kinase 2 (a protein tyrosine kinase)11530-0.119-0.2020Yes
47NEK3NEK3
Entrez,  Source
NIMA (never in mitosis gene a)-related kinase 311797-0.135-0.1943Yes
48HIPK1HIPK1
Entrez,  Source
homeodomain interacting protein kinase 111798-0.135-0.1662Yes
49PRPF4BPRPF4B
Entrez,  Source
PRP4 pre-mRNA processing factor 4 homolog B (yeast)11856-0.139-0.1418Yes
50ROCK2ROCK2
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 212033-0.152-0.1238Yes
51ABL1ABL1
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 112463-0.197-0.1156Yes
52CHUKCHUK
Entrez,  Source
conserved helix-loop-helix ubiquitous kinase12978-0.325-0.0875Yes
53SGK113133-0.4980.0037Yes
Table: GSEA details [plain text format]



Fig 2: MOMELOTINIB_LINCS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: MOMELOTINIB_LINCS: Random ES distribution   
Gene set null distribution of ES for MOMELOTINIB_LINCS