DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class0
GeneSetVEMURAFENIB_FDA
Enrichment Score (ES)-0.3614801
Normalized Enrichment Score (NES)-1.1703037
Nominal p-value0.21510297
FDR q-value0.7977584
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: VEMURAFENIB_FDA   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1PTK6PTK6
Entrez,  Source
PTK6 protein tyrosine kinase 61410.4790.0936No
2DDR1DDR1
Entrez,  Source
discoidin domain receptor family, member 12120.4040.1763No
3EPHB6EPHB6
Entrez,  Source
EPH receptor B67010.2150.1860No
4TNIKTNIK
Entrez,  Source
TRAF2 and NCK interacting kinase11970.1450.1801No
5LCKLCK
Entrez,  Source
lymphocyte-specific protein tyrosine kinase13100.1360.2012No
6STK3STK3
Entrez,  Source
serine/threonine kinase 3 (STE20 homolog, yeast)15530.1200.2088No
7TNK2TNK2
Entrez,  Source
tyrosine kinase, non-receptor, 230050.0700.1137No
8CSKCSK
Entrez,  Source
c-src tyrosine kinase30690.0690.1240No
9MINK1MINK1
Entrez,  Source
misshapen-like kinase 1 (zebrafish)30800.0690.1383No
10FLT3FLT3
Entrez,  Source
fms-related tyrosine kinase 334030.0630.1275No
11BLKBLK
Entrez,  Source
B lymphoid tyrosine kinase34190.0620.1399No
12CSF1RCSF1R
Entrez,  Source
colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog34540.0620.1508No
13BRAFBRAF
Entrez,  Source
v-raf murine sarcoma viral oncogene homolog B137720.0560.1389No
14FGRFGR
Entrez,  Source
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog41930.0490.1177No
15HUNKHUNK
Entrez,  Source
hormonally upregulated Neu-associated kinase46450.0430.0927No
16TGFBR2TGFBR2
Entrez,  Source
transforming growth factor, beta receptor II (70/80kDa)71030.007-0.0928No
17CDK1972630.004-0.1041No
18PI4KB7697-0.003-0.1364No
19PDGFRBPDGFRB
Entrez,  Source
platelet-derived growth factor receptor, beta polypeptide7824-0.006-0.1447No
20MAP2K1MAP2K1
Entrez,  Source
mitogen-activated protein kinase kinase 17939-0.008-0.1516No
21RAF1RAF1
Entrez,  Source
v-raf-1 murine leukemia viral oncogene homolog 18015-0.009-0.1553No
22KITKIT
Entrez,  Source
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog8134-0.012-0.1617No
23MAP2K5MAP2K5
Entrez,  Source
mitogen-activated protein kinase kinase 58199-0.013-0.1637No
24PRKD1PRKD1
Entrez,  Source
protein kinase D19827-0.052-0.2763No
25HCKHCK
Entrez,  Source
hemopoietic cell kinase9981-0.056-0.2757No
26SRCSRC
Entrez,  Source
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)10776-0.083-0.3180No
27RIPK2RIPK2
Entrez,  Source
receptor-interacting serine-threonine kinase 211349-0.110-0.3376Yes
28STK4STK4
Entrez,  Source
serine/threonine kinase 411518-0.118-0.3247Yes
29SLKSLK
Entrez,  Source
STE20-like kinase (yeast)11672-0.128-0.3085Yes
30MAP4K5MAP4K5
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 511705-0.130-0.2827Yes
31FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES11767-0.133-0.2583Yes
32MAP2K4MAP2K4
Entrez,  Source
mitogen-activated protein kinase kinase 411811-0.136-0.2318Yes
33MAP2K2MAP2K2
Entrez,  Source
mitogen-activated protein kinase kinase 211895-0.142-0.2073Yes
34CAMK1CAMK1
Entrez,  Source
calcium/calmodulin-dependent protein kinase I12150-0.162-0.1913Yes
35PDGFRAPDGFRA
Entrez,  Source
platelet-derived growth factor receptor, alpha polypeptide12211-0.168-0.1592Yes
36SIK112319-0.179-0.1284Yes
37ABL1ABL1
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 112463-0.197-0.0963Yes
38ZAKZAK
Entrez,  Source
-12544-0.209-0.0568Yes
39CDK8CDK8
Entrez,  Source
cyclin-dependent kinase 812650-0.226-0.0156Yes
40AXLAXL
Entrez,  Source
AXL receptor tyrosine kinase12789-0.2570.0299Yes
Table: GSEA details [plain text format]



Fig 2: VEMURAFENIB_FDA   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: VEMURAFENIB_FDA: Random ES distribution   
Gene set null distribution of ES for VEMURAFENIB_FDA