DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class0
GeneSetAZD-1152HQPA_KINOME SCAN
Enrichment Score (ES)-0.35404316
Normalized Enrichment Score (NES)-0.9693047
Nominal p-value0.4838013
FDR q-value0.97565174
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: AZD-1152HQPA_KINOME SCAN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)6250.2300.0628No
2EPHB6EPHB6
Entrez,  Source
EPH receptor B67010.2150.1602No
3LCKLCK
Entrez,  Source
lymphocyte-specific protein tyrosine kinase13100.1360.1791No
4ERBB4ERBB4
Entrez,  Source
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)18130.1070.1921No
5TIE1TIE1
Entrez,  Source
tyrosine kinase with immunoglobulin-like and EGF-like domains 123280.0880.1951No
6KDRKDR
Entrez,  Source
kinase insert domain receptor (a type III receptor tyrosine kinase)31460.0680.1655No
7FLT3FLT3
Entrez,  Source
fms-related tyrosine kinase 334030.0630.1761No
8AURKCAURKC
Entrez,  Source
aurora kinase C44130.0460.1214No
9FLT1FLT1
Entrez,  Source
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)48820.0390.1046No
10AURKAAURKA
Entrez,  Source
aurora kinase A64270.017-0.0046No
11RETRET
Entrez,  Source
ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)64710.016-0.0000No
12PDGFRBPDGFRB
Entrez,  Source
platelet-derived growth factor receptor, beta polypeptide7824-0.006-0.0999No
13KITKIT
Entrez,  Source
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog8134-0.012-0.1178No
14MAP2K5MAP2K5
Entrez,  Source
mitogen-activated protein kinase kinase 58199-0.013-0.1163No
15AURKBAURKB
Entrez,  Source
aurora kinase B8856-0.027-0.1530No
16CDK11A9060-0.032-0.1532No
17MAP4K5MAP4K5
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 511705-0.130-0.2919Yes
18PDGFRAPDGFRA
Entrez,  Source
platelet-derived growth factor receptor, alpha polypeptide12211-0.168-0.2498Yes
19ABL1ABL1
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 112463-0.197-0.1744Yes
20MAP3K7MAP3K7
Entrez,  Source
mitogen-activated protein kinase kinase kinase 712613-0.221-0.0800Yes
21AXLAXL
Entrez,  Source
AXL receptor tyrosine kinase12789-0.2570.0299Yes
Table: GSEA details [plain text format]



Fig 2: AZD-1152HQPA_KINOME SCAN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: AZD-1152HQPA_KINOME SCAN: Random ES distribution   
Gene set null distribution of ES for AZD-1152HQPA_KINOME SCAN