DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class0
GeneSetRO-3306_LINCS
Enrichment Score (ES)-0.32758516
Normalized Enrichment Score (NES)-1.0611154
Nominal p-value0.38425925
FDR q-value0.8386539
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: RO-3306_LINCS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1PRKCDPRKCD
Entrez,  Source
protein kinase C, delta3060.3370.0718No
2DYRK2DYRK2
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 212300.1420.0418No
3GAKGAK
Entrez,  Source
cyclin G associated kinase13400.1330.0711No
4STK17BSTK17B
Entrez,  Source
serine/threonine kinase 17b (apoptosis-inducing)15540.1190.0886No
5AAK1AAK1
Entrez,  Source
AP2 associated kinase 122120.0920.0647No
6CLK3CLK3
Entrez,  Source
CDC-like kinase 323490.0870.0790No
7TAOK1TAOK1
Entrez,  Source
TAO kinase 125520.0820.0867No
8RPS6KA5RPS6KA5
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 526100.0800.1050No
9FLT3FLT3
Entrez,  Source
fms-related tyrosine kinase 334030.0630.0624No
10PIM1PIM1
Entrez,  Source
pim-1 oncogene41360.0500.0209No
11PHKG2PHKG2
Entrez,  Source
phosphorylase kinase, gamma 2 (testis)47920.040-0.0175No
12PIK3CGPIK3CG
Entrez,  Source
phosphoinositide-3-kinase, catalytic, gamma polypeptide53290.033-0.0490No
13PRKXPRKX
Entrez,  Source
protein kinase, X-linked59930.024-0.0928No
14IRAK1IRAK1
Entrez,  Source
interleukin-1 receptor-associated kinase 161790.021-0.1010No
15CSNK1G2CSNK1G2
Entrez,  Source
casein kinase 1, gamma 263280.018-0.1070No
16MAP4K2MAP4K2
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 268940.010-0.1472No
17CLK4CLK4
Entrez,  Source
CDC-like kinase 469350.010-0.1475No
18BMP2KBMP2K
Entrez,  Source
BMP2 inducible kinase70290.008-0.1523No
19CLK2CLK2
Entrez,  Source
CDC-like kinase 271810.005-0.1624No
20MELKMELK
Entrez,  Source
maternal embryonic leucine zipper kinase8047-0.010-0.2254No
21RPS6KA4RPS6KA4
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 48181-0.013-0.2319No
22DYRK1BDYRK1B
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B8200-0.013-0.2296No
23DMPKDMPK
Entrez,  Source
dystrophia myotonica-protein kinase8344-0.016-0.2359No
24ROCK1ROCK1
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 18741-0.025-0.2590No
25MAPKAPK2MAPKAPK2
Entrez,  Source
mitogen-activated protein kinase-activated protein kinase 29187-0.035-0.2830No
26CSNK2A2CSNK2A2
Entrez,  Source
casein kinase 2, alpha prime polypeptide9758-0.049-0.3125Yes
27HIPK3HIPK3
Entrez,  Source
homeodomain interacting protein kinase 39770-0.050-0.2993Yes
28MAP4K4MAP4K4
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 49922-0.055-0.2954Yes
29STK17ASTK17A
Entrez,  Source
serine/threonine kinase 17a (apoptosis-inducing)10017-0.057-0.2864Yes
30DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A10303-0.066-0.2894Yes
31CITCIT
Entrez,  Source
citron (rho-interacting, serine/threonine kinase 21)10420-0.070-0.2785Yes
32DAPK3DAPK3
Entrez,  Source
death-associated protein kinase 311066-0.096-0.3004Yes
33CDK7CDK7
Entrez,  Source
cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)11160-0.101-0.2790Yes
34MYLKMYLK
Entrez,  Source
myosin, light chain kinase11255-0.105-0.2565Yes
35BMPR2BMPR2
Entrez,  Source
bone morphogenetic protein receptor, type II (serine/threonine kinase)11345-0.109-0.2324Yes
36CSNK2A1CSNK2A1
Entrez,  Source
casein kinase 2, alpha 1 polypeptide11861-0.139-0.2322Yes
37ROCK2ROCK2
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 212033-0.152-0.2023Yes
38CDC42BPBCDC42BPB
Entrez,  Source
CDC42 binding protein kinase beta (DMPK-like)12053-0.154-0.1602Yes
39PKN2PKN2
Entrez,  Source
protein kinase N212286-0.175-0.1284Yes
40CSNK1G3CSNK1G3
Entrez,  Source
casein kinase 1, gamma 312464-0.197-0.0861Yes
41SGK113133-0.4980.0037Yes
Table: GSEA details [plain text format]



Fig 2: RO-3306_LINCS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: RO-3306_LINCS: Random ES distribution   
Gene set null distribution of ES for RO-3306_LINCS