DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class0
GeneSetBX-795_MRC
Enrichment Score (ES)-0.34810582
Normalized Enrichment Score (NES)-1.1917218
Nominal p-value0.16306955
FDR q-value0.7966648
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: BX-795_MRC   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1MST43180.3310.0383No
2SYKSYK
Entrez,  Source
spleen tyrosine kinase4710.2680.0774No
3DYRK2DYRK2
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 212300.1420.0465No
4LCKLCK
Entrez,  Source
lymphocyte-specific protein tyrosine kinase13100.1360.0662No
5STK3STK3
Entrez,  Source
serine/threonine kinase 3 (STE20 homolog, yeast)15530.1200.0704No
6RPS6KA1RPS6KA1
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 116860.1130.0816No
7MAP3K9MAP3K9
Entrez,  Source
mitogen-activated protein kinase kinase kinase 916990.1120.1019No
8MAPK3MAPK3
Entrez,  Source
mitogen-activated protein kinase 317660.1090.1175No
9MARK1MARK1
Entrez,  Source
MAP/microtubule affinity-regulating kinase 121590.0930.1052No
10MAP3K11MAP3K11
Entrez,  Source
mitogen-activated protein kinase kinase kinase 1122950.0890.1118No
11MKNK1MKNK1
Entrez,  Source
MAP kinase interacting serine/threonine kinase 129070.0730.0790No
12YES1YES1
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 130360.0700.0824No
13MARK2MARK2
Entrez,  Source
MAP/microtubule affinity-regulating kinase 238340.0550.0321No
14AURKCAURKC
Entrez,  Source
aurora kinase C44130.046-0.0033No
15NEK2NEK2
Entrez,  Source
NIMA (never in mitosis gene a)-related kinase 244830.045-0.0000No
16FLT1FLT1
Entrez,  Source
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)48820.039-0.0230No
17PAK4PAK4
Entrez,  Source
p21(CDKN1A)-activated kinase 450140.037-0.0259No
18INSRRINSRR
Entrez,  Source
insulin receptor-related receptor53320.033-0.0439No
19PAK7PAK7
Entrez,  Source
p21(CDKN1A)-activated kinase 758810.025-0.0808No
20MAPK1MAPK1
Entrez,  Source
mitogen-activated protein kinase 159940.024-0.0849No
21AURKAAURKA
Entrez,  Source
aurora kinase A64270.017-0.1146No
22MAP4K2MAP4K2
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 268940.010-0.1482No
23CLK2CLK2
Entrez,  Source
CDC-like kinase 271810.005-0.1690No
24IKBKEIKBKE
Entrez,  Source
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon72160.004-0.1707No
25PRKAA2PRKAA2
Entrez,  Source
protein kinase, AMP-activated, alpha 2 catalytic subunit74180.001-0.1858No
26MKNK2MKNK2
Entrez,  Source
MAP kinase interacting serine/threonine kinase 27841-0.006-0.2168No
27MAP2K1MAP2K1
Entrez,  Source
mitogen-activated protein kinase kinase 17939-0.008-0.2227No
28MELKMELK
Entrez,  Source
maternal embryonic leucine zipper kinase8047-0.010-0.2290No
29PRKACAPRKACA
Entrez,  Source
protein kinase, cAMP-dependent, catalytic, alpha8112-0.011-0.2317No
30MARK4MARK4
Entrez,  Source
MAP/microtubule affinity-regulating kinase 48259-0.014-0.2402No
31PDK1PDK1
Entrez,  Source
pyruvate dehydrogenase kinase, isozyme 18449-0.018-0.2511No
32AURKBAURKB
Entrez,  Source
aurora kinase B8856-0.027-0.2768No
33PHKA2PHKA2
Entrez,  Source
phosphorylase kinase, alpha 2 (liver)9057-0.032-0.2861No
34CDK2CDK2
Entrez,  Source
cyclin-dependent kinase 29409-0.040-0.3052No
35PRKD1PRKD1
Entrez,  Source
protein kinase D19827-0.052-0.3272No
36CHEK2CHEK2
Entrez,  Source
CHK2 checkpoint homolog (S. pombe)10102-0.059-0.3369Yes
37HIPK2HIPK2
Entrez,  Source
homeodomain interacting protein kinase 210151-0.061-0.3290Yes
38MARK3MARK3
Entrez,  Source
MAP/microtubule affinity-regulating kinase 310374-0.068-0.3331Yes
39RPS6KA3RPS6KA3
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 310427-0.070-0.3237Yes
40RPS6KB1RPS6KB1
Entrez,  Source
ribosomal protein S6 kinase, 70kDa, polypeptide 110717-0.081-0.3305Yes
41CAMKK2CAMKK2
Entrez,  Source
calcium/calmodulin-dependent protein kinase kinase 2, beta10729-0.081-0.3160Yes
42TBK1TBK1
Entrez,  Source
TANK-binding kinase 110732-0.082-0.3007Yes
43BRSK2BRSK2
Entrez,  Source
BR serine/threonine kinase 210749-0.082-0.2865Yes
44SRCSRC
Entrez,  Source
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)10776-0.083-0.2727Yes
45CHEK1CHEK1
Entrez,  Source
CHK1 checkpoint homolog (S. pombe)10792-0.084-0.2579Yes
46NUAK1NUAK1
Entrez,  Source
NUAK family, SNF1-like kinase, 111032-0.095-0.2583Yes
47GSK3BGSK3B
Entrez,  Source
glycogen synthase kinase 3 beta11131-0.100-0.2469Yes
48JAK2JAK2
Entrez,  Source
Janus kinase 2 (a protein tyrosine kinase)11530-0.119-0.2548Yes
49PRKCAPRKCA
Entrez,  Source
protein kinase C, alpha11975-0.147-0.2608Yes
50ROCK2ROCK2
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 212033-0.152-0.2364Yes
51CAMK1CAMK1
Entrez,  Source
calcium/calmodulin-dependent protein kinase I12150-0.162-0.2147Yes
52DYRK3DYRK3
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 312238-0.171-0.1891Yes
53PKN2PKN2
Entrez,  Source
protein kinase N212286-0.175-0.1595Yes
54MAP3K7MAP3K7
Entrez,  Source
mitogen-activated protein kinase kinase kinase 712613-0.221-0.1427Yes
55FGFR1FGFR1
Entrez,  Source
fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)13121-0.486-0.0895Yes
56SGK113133-0.4980.0037Yes
Table: GSEA details [plain text format]



Fig 2: BX-795_MRC   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: BX-795_MRC: Random ES distribution   
Gene set null distribution of ES for BX-795_MRC