DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class0
GeneSetPLX4032_LINCS
Enrichment Score (ES)-0.3507507
Normalized Enrichment Score (NES)-1.1202215
Nominal p-value0.29594272
FDR q-value0.8773496
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: PLX4032_LINCS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1PTK6PTK6
Entrez,  Source
PTK6 protein tyrosine kinase 61410.4790.0992No
2DDR1DDR1
Entrez,  Source
discoidin domain receptor family, member 12120.4040.1865No
3EPHB6EPHB6
Entrez,  Source
EPH receptor B67010.2150.1987No
4TNIKTNIK
Entrez,  Source
TRAF2 and NCK interacting kinase11970.1450.1945No
5LCKLCK
Entrez,  Source
lymphocyte-specific protein tyrosine kinase13100.1360.2171No
6STK3STK3
Entrez,  Source
serine/threonine kinase 3 (STE20 homolog, yeast)15530.1200.2262No
7TNK2TNK2
Entrez,  Source
tyrosine kinase, non-receptor, 230050.0700.1319No
8CSKCSK
Entrez,  Source
c-src tyrosine kinase30690.0690.1430No
9FLT3FLT3
Entrez,  Source
fms-related tyrosine kinase 334030.0630.1320No
10BLKBLK
Entrez,  Source
B lymphoid tyrosine kinase34190.0620.1452No
11CSF1RCSF1R
Entrez,  Source
colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog34540.0620.1568No
12BRAFBRAF
Entrez,  Source
v-raf murine sarcoma viral oncogene homolog B137720.0560.1456No
13FGRFGR
Entrez,  Source
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog41930.0490.1249No
14HUNKHUNK
Entrez,  Source
hormonally upregulated Neu-associated kinase46450.0430.1004No
15TGFBR2TGFBR2
Entrez,  Source
transforming growth factor, beta receptor II (70/80kDa)71030.007-0.0850No
16CDK1972630.004-0.0963No
17PI4KB7697-0.003-0.1285No
18PDGFRBPDGFRB
Entrez,  Source
platelet-derived growth factor receptor, beta polypeptide7824-0.006-0.1367No
19MAP2K1MAP2K1
Entrez,  Source
mitogen-activated protein kinase kinase 17939-0.008-0.1435No
20RAF1RAF1
Entrez,  Source
v-raf-1 murine leukemia viral oncogene homolog 18015-0.009-0.1471No
21KITKIT
Entrez,  Source
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog8134-0.012-0.1534No
22MAP2K5MAP2K5
Entrez,  Source
mitogen-activated protein kinase kinase 58199-0.013-0.1553No
23PRKD1PRKD1
Entrez,  Source
protein kinase D19827-0.052-0.2672No
24HCKHCK
Entrez,  Source
hemopoietic cell kinase9981-0.056-0.2660No
25SRCSRC
Entrez,  Source
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)10776-0.083-0.3072No
26RIPK2RIPK2
Entrez,  Source
receptor-interacting serine-threonine kinase 211349-0.110-0.3256Yes
27STK4STK4
Entrez,  Source
serine/threonine kinase 411518-0.118-0.3113Yes
28SLKSLK
Entrez,  Source
STE20-like kinase (yeast)11672-0.128-0.2937Yes
29MAP4K5MAP4K5
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 511705-0.130-0.2663Yes
30FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES11767-0.133-0.2404Yes
31MAP2K4MAP2K4
Entrez,  Source
mitogen-activated protein kinase kinase 411811-0.136-0.2124Yes
32MAP2K2MAP2K2
Entrez,  Source
mitogen-activated protein kinase kinase 211895-0.142-0.1862Yes
33PDGFRAPDGFRA
Entrez,  Source
platelet-derived growth factor receptor, alpha polypeptide12211-0.168-0.1716Yes
34SIK112319-0.179-0.1387Yes
35ABL1ABL1
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 112463-0.197-0.1043Yes
36ZAKZAK
Entrez,  Source
-12544-0.209-0.0624Yes
37CDK8CDK8
Entrez,  Source
cyclin-dependent kinase 812650-0.226-0.0186Yes
38AXLAXL
Entrez,  Source
AXL receptor tyrosine kinase12789-0.2570.0299Yes
Table: GSEA details [plain text format]



Fig 2: PLX4032_LINCS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: PLX4032_LINCS: Random ES distribution   
Gene set null distribution of ES for PLX4032_LINCS