| Dataset | NSCLC_collapsed_to_symbols.NSCLC.cls #SEN_versus_RES.NSCLC.cls #SEN_versus_RES_repos |
| Phenotype | NSCLC.cls#SEN_versus_RES_repos |
| Upregulated in class | 1 |
| GeneSet | BOSUTINIB_LINCS |
| Enrichment Score (ES) | 0.41692895 |
| Normalized Enrichment Score (NES) | 1.4036812 |
| Nominal p-value | 0.048986487 |
| FDR q-value | 0.57902825 |
| FWER p-Value | 1.0 |

| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ERBB3 | ERBB3 Entrez,  Source | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 12 | 1.034 | 0.1263 | Yes |
| 2 | ERBB2 | ERBB2 Entrez,  Source | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 100 | 0.537 | 0.1858 | Yes |
| 3 | FRK | FRK Entrez,  Source | fyn-related kinase | 296 | 0.343 | 0.2131 | Yes |
| 4 | PRKCD | PRKCD Entrez,  Source | protein kinase C, delta | 306 | 0.337 | 0.2538 | Yes |
| 5 | MST4 | 318 | 0.331 | 0.2937 | Yes | ||
| 6 | SYK | SYK Entrez,  Source | spleen tyrosine kinase | 471 | 0.268 | 0.3151 | Yes |
| 7 | EGFR | EGFR Entrez,  Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 625 | 0.230 | 0.3317 | Yes |
| 8 | PAK1 | PAK1 Entrez,  Source | p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) | 674 | 0.219 | 0.3550 | Yes |
| 9 | TNIK | TNIK Entrez,  Source | TRAF2 and NCK interacting kinase | 1197 | 0.145 | 0.3331 | Yes |
| 10 | LCK | LCK Entrez,  Source | lymphocyte-specific protein tyrosine kinase | 1310 | 0.136 | 0.3412 | Yes |
| 11 | GAK | GAK Entrez,  Source | cyclin G associated kinase | 1340 | 0.133 | 0.3554 | Yes |
| 12 | CAMK1D | CAMK1D Entrez,  Source | calcium/calmodulin-dependent protein kinase ID | 1387 | 0.129 | 0.3678 | Yes |
| 13 | STK3 | STK3 Entrez,  Source | serine/threonine kinase 3 (STE20 homolog, yeast) | 1553 | 0.120 | 0.3699 | Yes |
| 14 | WEE1 | WEE1 Entrez,  Source | WEE1 homolog (S. pombe) | 1639 | 0.115 | 0.3776 | Yes |
| 15 | MAP3K9 | MAP3K9 Entrez,  Source | mitogen-activated protein kinase kinase kinase 9 | 1699 | 0.112 | 0.3869 | Yes |
| 16 | ERBB4 | ERBB4 Entrez,  Source | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 1813 | 0.107 | 0.3914 | Yes |
| 17 | CSNK1D | CSNK1D Entrez,  Source | casein kinase 1, delta | 1851 | 0.105 | 0.4015 | Yes |
| 18 | RIOK3 | RIOK3 Entrez,  Source | RIO kinase 3 (yeast) | 1942 | 0.101 | 0.4070 | Yes |
| 19 | LYN | LYN Entrez,  Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 1974 | 0.100 | 0.4169 | Yes |
| 20 | AAK1 | AAK1 Entrez,  Source | AP2 associated kinase 1 | 2212 | 0.092 | 0.4102 | No |
| 21 | MAP3K11 | MAP3K11 Entrez,  Source | mitogen-activated protein kinase kinase kinase 11 | 2295 | 0.089 | 0.4149 | No |
| 22 | MAP3K4 | MAP3K4 Entrez,  Source | mitogen-activated protein kinase kinase kinase 4 | 2489 | 0.083 | 0.4104 | No |
| 23 | EPHA3 | EPHA3 Entrez,  Source | EPH receptor A3 | 2870 | 0.074 | 0.3905 | No |
| 24 | EIF2AK1 | EIF2AK1 Entrez,  Source | eukaryotic translation initiation factor 2-alpha kinase 1 | 3008 | 0.070 | 0.3887 | No |
| 25 | YES1 | YES1 Entrez,  Source | v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 | 3036 | 0.070 | 0.3952 | No |
| 26 | CSK | CSK Entrez,  Source | c-src tyrosine kinase | 3069 | 0.069 | 0.4013 | No |
| 27 | MINK1 | MINK1 Entrez,  Source | misshapen-like kinase 1 (zebrafish) | 3080 | 0.069 | 0.4090 | No |
| 28 | BLK | BLK Entrez,  Source | B lymphoid tyrosine kinase | 3419 | 0.062 | 0.3909 | No |
| 29 | CSF1R | CSF1R Entrez,  Source | colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog | 3454 | 0.062 | 0.3959 | No |
| 30 | CSNK1A1 | CSNK1A1 Entrez,  Source | casein kinase 1, alpha 1 | 3698 | 0.058 | 0.3844 | No |
| 31 | FGR | FGR Entrez,  Source | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 4193 | 0.049 | 0.3528 | No |
| 32 | NEK2 | NEK2 Entrez,  Source | NIMA (never in mitosis gene a)-related kinase 2 | 4483 | 0.045 | 0.3363 | No |
| 33 | EPHA2 | EPHA2 Entrez,  Source | EPH receptor A2 | 4880 | 0.039 | 0.3109 | No |
| 34 | MAPK4 | MAPK4 Entrez,  Source | mitogen-activated protein kinase 4 | 5585 | 0.029 | 0.2609 | No |
| 35 | STK24 | STK24 Entrez,  Source | serine/threonine kinase 24 (STE20 homolog, yeast) | 5587 | 0.029 | 0.2644 | No |
| 36 | BTK | BTK Entrez,  Source | Bruton agammaglobulinemia tyrosine kinase | 5628 | 0.029 | 0.2649 | No |
| 37 | SRPK3 | SRPK3 Entrez,  Source | SFRS protein kinase 3 | 5860 | 0.026 | 0.2504 | No |
| 38 | MAP3K3 | MAP3K3 Entrez,  Source | mitogen-activated protein kinase kinase kinase 3 | 5921 | 0.025 | 0.2489 | No |
| 39 | FES | FES Entrez,  Source | feline sarcoma oncogene | 6126 | 0.022 | 0.2360 | No |
| 40 | RET | RET Entrez,  Source | ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease) | 6471 | 0.016 | 0.2118 | No |
| 41 | PIP4K2B | 6594 | 0.015 | 0.2043 | No | ||
| 42 | GRK4 | GRK4 Entrez,  Source | G protein-coupled receptor kinase 4 | 6788 | 0.012 | 0.1910 | No |
| 43 | MAP4K2 | MAP4K2 Entrez,  Source | mitogen-activated protein kinase kinase kinase kinase 2 | 6894 | 0.010 | 0.1843 | No |
| 44 | BMP2K | BMP2K Entrez,  Source | BMP2 inducible kinase | 7029 | 0.008 | 0.1750 | No |
| 45 | SIK2 | 7435 | 0.001 | 0.1443 | No | ||
| 46 | SIK3 | 7726 | -0.004 | 0.1226 | No | ||
| 47 | CSNK1E | CSNK1E Entrez,  Source | casein kinase 1, epsilon | 7742 | -0.004 | 0.1220 | No |
| 48 | MAP2K1 | MAP2K1 Entrez,  Source | mitogen-activated protein kinase kinase 1 | 7939 | -0.008 | 0.1080 | No |
| 49 | MAP2K5 | MAP2K5 Entrez,  Source | mitogen-activated protein kinase kinase 5 | 8199 | -0.013 | 0.0899 | No |
| 50 | DMPK | DMPK Entrez,  Source | dystrophia myotonica-protein kinase | 8344 | -0.016 | 0.0809 | No |
| 51 | VRK2 | VRK2 Entrez,  Source | vaccinia related kinase 2 | 8412 | -0.017 | 0.0780 | No |
| 52 | STK25 | STK25 Entrez,  Source | serine/threonine kinase 25 (STE20 homolog, yeast) | 8561 | -0.021 | 0.0692 | No |
| 53 | MAP4K4 | MAP4K4 Entrez,  Source | mitogen-activated protein kinase kinase kinase kinase 4 | 9922 | -0.055 | -0.0278 | No |
| 54 | HCK | HCK Entrez,  Source | hemopoietic cell kinase | 9981 | -0.056 | -0.0253 | No |
| 55 | CIT | CIT Entrez,  Source | citron (rho-interacting, serine/threonine kinase 21) | 10420 | -0.070 | -0.0501 | No |
| 56 | SRC | SRC Entrez,  Source | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 10776 | -0.083 | -0.0669 | No |
| 57 | ABL2 | ABL2 Entrez,  Source | v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene) | 11090 | -0.098 | -0.0788 | No |
| 58 | STK10 | STK10 Entrez,  Source | serine/threonine kinase 10 | 11218 | -0.103 | -0.0758 | No |
| 59 | BMPR2 | BMPR2 Entrez,  Source | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 11345 | -0.109 | -0.0719 | No |
| 60 | JAK2 | JAK2 Entrez,  Source | Janus kinase 2 (a protein tyrosine kinase) | 11530 | -0.119 | -0.0713 | No |
| 61 | SLK | SLK Entrez,  Source | STE20-like kinase (yeast) | 11672 | -0.128 | -0.0664 | No |
| 62 | MAP4K5 | MAP4K5 Entrez,  Source | mitogen-activated protein kinase kinase kinase kinase 5 | 11705 | -0.130 | -0.0529 | No |
| 63 | MAP2K2 | MAP2K2 Entrez,  Source | mitogen-activated protein kinase kinase 2 | 11895 | -0.142 | -0.0499 | No |
| 64 | MAP3K2 | MAP3K2 Entrez,  Source | mitogen-activated protein kinase kinase kinase 2 | 12210 | -0.168 | -0.0532 | No |
| 65 | MAPK6 | MAPK6 Entrez,  Source | mitogen-activated protein kinase 6 | 12214 | -0.168 | -0.0327 | No |
| 66 | MAP4K3 | MAP4K3 Entrez,  Source | mitogen-activated protein kinase kinase kinase kinase 3 | 12403 | -0.189 | -0.0238 | No |
| 67 | ABL1 | ABL1 Entrez,  Source | v-abl Abelson murine leukemia viral oncogene homolog 1 | 12463 | -0.197 | -0.0040 | No |
| 68 | MAP3K7 | MAP3K7 Entrez,  Source | mitogen-activated protein kinase kinase kinase 7 | 12613 | -0.221 | 0.0117 | No |
| 69 | AXL | AXL Entrez,  Source | AXL receptor tyrosine kinase | 12789 | -0.257 | 0.0300 | No |

