DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class1
GeneSetMLN8054_LINCS
Enrichment Score (ES)0.33943117
Normalized Enrichment Score (NES)1.0357455
Nominal p-value0.3988658
FDR q-value0.7384057
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: MLN8054_LINCS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1EPHA1EPHA1
Entrez,  Source
EPH receptor A1940.5450.0967Yes
2FGFR3FGFR3
Entrez,  Source
fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)1530.4650.1809Yes
3FGFR2FGFR2
Entrez,  Source
ffer syndrome, Jackson-Weiss syndrome)2100.4060.2539Yes
4DDR1DDR1
Entrez,  Source
discoidin domain receptor family, member 12120.4040.3307Yes
5EPHA4EPHA4
Entrez,  Source
EPH receptor A47980.1970.3237Yes
6LCKLCK
Entrez,  Source
lymphocyte-specific protein tyrosine kinase13100.1360.3107Yes
7EPHA7EPHA7
Entrez,  Source
EPH receptor A714120.1280.3274Yes
8STK17BSTK17B
Entrez,  Source
serine/threonine kinase 17b (apoptosis-inducing)15540.1190.3394Yes
9TIE1TIE1
Entrez,  Source
tyrosine kinase with immunoglobulin-like and EGF-like domains 123280.0880.2973No
10CLK3CLK3
Entrez,  Source
CDC-like kinase 323490.0870.3124No
11MERTKMERTK
Entrez,  Source
c-mer proto-oncogene tyrosine kinase25220.0820.3151No
12EPHA3EPHA3
Entrez,  Source
EPH receptor A328700.0740.3027No
13YES1YES1
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 130360.0700.3034No
14CSKCSK
Entrez,  Source
c-src tyrosine kinase30690.0690.3141No
15BLKBLK
Entrez,  Source
B lymphoid tyrosine kinase34190.0620.2995No
16EPHB4EPHB4
Entrez,  Source
EPH receptor B438790.0540.2749No
17EPHB1EPHB1
Entrez,  Source
EPH receptor B140000.0520.2757No
18FGRFGR
Entrez,  Source
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog41930.0490.2705No
19EPHA2EPHA2
Entrez,  Source
EPH receptor A248800.0390.2258No
20FLT1FLT1
Entrez,  Source
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)48820.0390.2331No
21TECTEC
Entrez,  Source
tec protein tyrosine kinase53790.0320.2015No
22EPHA5EPHA5
Entrez,  Source
EPH receptor A554750.0310.2002No
23AURKAAURKA
Entrez,  Source
aurora kinase A64270.0170.1311No
24TEKTEK
Entrez,  Source
TEK tyrosine kinase, endothelial (venous malformations, multiple cutaneous and mucosal)70350.0080.0864No
25CLK2CLK2
Entrez,  Source
CDC-like kinase 271810.0050.0763No
26PIK3CAPIK3CA
Entrez,  Source
phosphoinositide-3-kinase, catalytic, alpha polypeptide8749-0.025-0.0381No
27AURKBAURKB
Entrez,  Source
aurora kinase B8856-0.027-0.0410No
28CSNK2A2CSNK2A2
Entrez,  Source
casein kinase 2, alpha prime polypeptide9758-0.049-0.1001No
29HCKHCK
Entrez,  Source
hemopoietic cell kinase9981-0.056-0.1063No
30STK17ASTK17A
Entrez,  Source
serine/threonine kinase 17a (apoptosis-inducing)10017-0.057-0.0981No
31DDR2DDR2
Entrez,  Source
discoidin domain receptor family, member 210235-0.064-0.1025No
32PLK4PLK4
Entrez,  Source
polo-like kinase 4 (Drosophila)10581-0.075-0.1144No
33SRCSRC
Entrez,  Source
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)10776-0.083-0.1133No
34STK10STK10
Entrez,  Source
serine/threonine kinase 1011218-0.103-0.1272No
35HIPK1HIPK1
Entrez,  Source
homeodomain interacting protein kinase 111798-0.135-0.1454No
36SIK112319-0.179-0.1509No
37IRAK3IRAK3
Entrez,  Source
interleukin-1 receptor-associated kinase 312451-0.196-0.1236No
38ABL1ABL1
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 112463-0.197-0.0869No
39AXLAXL
Entrez,  Source
AXL receptor tyrosine kinase12789-0.257-0.0627No
40FGFR1FGFR1
Entrez,  Source
fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)13121-0.4860.0046No
Table: GSEA details [plain text format]



Fig 2: MLN8054_LINCS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: MLN8054_LINCS: Random ES distribution   
Gene set null distribution of ES for MLN8054_LINCS