DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class1
GeneSetNILOTINIB_KINOME SCAN
Enrichment Score (ES)0.43644676
Normalized Enrichment Score (NES)1.2941245
Nominal p-value0.11490126
FDR q-value0.6369445
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: NILOTINIB_KINOME SCAN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1EPHA1EPHA1
Entrez,  Source
EPH receptor A1940.5450.1280Yes
2DDR1DDR1
Entrez,  Source
discoidin domain receptor family, member 12120.4040.2191Yes
3FRKFRK
Entrez,  Source
fyn-related kinase2960.3430.2978Yes
4EPHB6EPHB6
Entrez,  Source
EPH receptor B67010.2150.3204Yes
5EPHA4EPHA4
Entrez,  Source
EPH receptor A47980.1970.3620Yes
6EPHB2EPHB2
Entrez,  Source
EPH receptor B28680.1850.4026Yes
7LCKLCK
Entrez,  Source
lymphocyte-specific protein tyrosine kinase13100.1360.4028Yes
8EPHB3EPHB3
Entrez,  Source
EPH receptor B314260.1270.4255Yes
9NTRK2NTRK2
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 217040.1120.4322Yes
10LYNLYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog19740.1000.4364Yes
11TIE1TIE1
Entrez,  Source
tyrosine kinase with immunoglobulin-like and EGF-like domains 123280.0880.4314No
12MAP4K1MAP4K1
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 128490.0740.4102No
13EPHA3EPHA3
Entrez,  Source
EPH receptor A328700.0740.4269No
14BLKBLK
Entrez,  Source
B lymphoid tyrosine kinase34190.0620.4006No
15CSF1RCSF1R
Entrez,  Source
colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog34540.0620.4134No
16BRAFBRAF
Entrez,  Source
v-raf murine sarcoma viral oncogene homolog B137720.0560.4032No
17EPHB4EPHB4
Entrez,  Source
EPH receptor B438790.0540.4086No
18FGRFGR
Entrez,  Source
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog41930.0490.3970No
19EPHA2EPHA2
Entrez,  Source
EPH receptor A248800.0390.3545No
20TNNI3KTNNI3K
Entrez,  Source
TNNI3 interacting kinase52740.0330.3329No
21MAPK11MAPK11
Entrez,  Source
mitogen-activated protein kinase 1153920.0320.3319No
22RETRET
Entrez,  Source
ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)64710.0160.2540No
23MAPK14MAPK14
Entrez,  Source
mitogen-activated protein kinase 1464920.0160.2565No
24MAPK8MAPK8
Entrez,  Source
mitogen-activated protein kinase 868290.0110.2336No
25TEKTEK
Entrez,  Source
TEK tyrosine kinase, endothelial (venous malformations, multiple cutaneous and mucosal)70350.0080.2200No
26PDGFRBPDGFRB
Entrez,  Source
platelet-derived growth factor receptor, beta polypeptide7824-0.0060.1615No
27KITKIT
Entrez,  Source
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog8134-0.0120.1409No
28MAP2K5MAP2K5
Entrez,  Source
mitogen-activated protein kinase kinase 58199-0.0130.1393No
29NTRK3NTRK3
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 38500-0.0190.1213No
30HCKHCK
Entrez,  Source
hemopoietic cell kinase9981-0.0560.0227No
31DDR2DDR2
Entrez,  Source
discoidin domain receptor family, member 210235-0.0640.0192No
32ABL2ABL2
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)11090-0.098-0.0216No
33CDC42BPBCDC42BPB
Entrez,  Source
CDC42 binding protein kinase beta (DMPK-like)12053-0.154-0.0566No
34PDGFRAPDGFRA
Entrez,  Source
platelet-derived growth factor receptor, alpha polypeptide12211-0.168-0.0270No
35ABL1ABL1
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 112463-0.1970.0028No
36ZAKZAK
Entrez,  Source
-12544-0.2090.0485No
Table: GSEA details [plain text format]



Fig 2: NILOTINIB_KINOME SCAN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: NILOTINIB_KINOME SCAN: Random ES distribution   
Gene set null distribution of ES for NILOTINIB_KINOME SCAN