DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class0
GeneSetPLX-4720_LINCS
Enrichment Score (ES)-0.3109114
Normalized Enrichment Score (NES)-0.9979095
Nominal p-value0.46680498
FDR q-value1.0
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: PLX-4720_LINCS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1PTK6PTK6
Entrez,  Source
PTK6 protein tyrosine kinase 61410.4790.0976No
2DDR1DDR1
Entrez,  Source
discoidin domain receptor family, member 12120.4040.1836No
3PAK1PAK1
Entrez,  Source
p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)6740.2190.1980No
4EPHB6EPHB6
Entrez,  Source
EPH receptor B67010.2150.2447No
5LCKLCK
Entrez,  Source
lymphocyte-specific protein tyrosine kinase13100.1360.2292No
6NEK11NEK11
Entrez,  Source
NIMA (never in mitosis gene a)- related kinase 1115220.1220.2407No
7TESK1TESK1
Entrez,  Source
testis-specific kinase 118550.1050.2391No
8TNK2TNK2
Entrez,  Source
tyrosine kinase, non-receptor, 230050.0700.1676No
9CSKCSK
Entrez,  Source
c-src tyrosine kinase30690.0690.1785No
10FLT3FLT3
Entrez,  Source
fms-related tyrosine kinase 334030.0630.1673No
11BLKBLK
Entrez,  Source
B lymphoid tyrosine kinase34190.0620.1803No
12CSF1RCSF1R
Entrez,  Source
colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog34540.0620.1916No
13BRAFBRAF
Entrez,  Source
v-raf murine sarcoma viral oncogene homolog B137720.0560.1802No
14ALKALK
Entrez,  Source
anaplastic lymphoma kinase (Ki-1)40730.0510.1690No
15FGRFGR
Entrez,  Source
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog41930.0490.1711No
16BMPR1BBMPR1B
Entrez,  Source
bone morphogenetic protein receptor, type IB67770.012-0.0227No
17TGFBR2TGFBR2
Entrez,  Source
transforming growth factor, beta receptor II (70/80kDa)71030.007-0.0459No
18CLK2CLK2
Entrez,  Source
CDC-like kinase 271810.005-0.0506No
19CDK1972630.004-0.0560No
20PDGFRBPDGFRB
Entrez,  Source
platelet-derived growth factor receptor, beta polypeptide7824-0.006-0.0972No
21MAP2K1MAP2K1
Entrez,  Source
mitogen-activated protein kinase kinase 17939-0.008-0.1041No
22RAF1RAF1
Entrez,  Source
v-raf-1 murine leukemia viral oncogene homolog 18015-0.009-0.1077No
23KITKIT
Entrez,  Source
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog8134-0.012-0.1140No
24MAP2K5MAP2K5
Entrez,  Source
mitogen-activated protein kinase kinase 58199-0.013-0.1159No
25CSNK2A2CSNK2A2
Entrez,  Source
casein kinase 2, alpha prime polypeptide9758-0.049-0.2233No
26DDR2DDR2
Entrez,  Source
discoidin domain receptor family, member 210235-0.064-0.2452No
27SRCSRC
Entrez,  Source
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)10776-0.083-0.2674No
28RIPK2RIPK2
Entrez,  Source
receptor-interacting serine-threonine kinase 211349-0.110-0.2861Yes
29SLKSLK
Entrez,  Source
STE20-like kinase (yeast)11672-0.128-0.2817Yes
30FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES11767-0.133-0.2588Yes
31MAP2K4MAP2K4
Entrez,  Source
mitogen-activated protein kinase kinase 411811-0.136-0.2312Yes
32MAP2K2MAP2K2
Entrez,  Source
mitogen-activated protein kinase kinase 211895-0.142-0.2054Yes
33CAMK1CAMK1
Entrez,  Source
calcium/calmodulin-dependent protein kinase I12150-0.162-0.1881Yes
34PDGFRAPDGFRA
Entrez,  Source
platelet-derived growth factor receptor, alpha polypeptide12211-0.168-0.1547Yes
35SIK112319-0.179-0.1223Yes
36ABL1ABL1
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 112463-0.197-0.0886Yes
37RIOK2RIOK2
Entrez,  Source
RIO kinase 2 (yeast)12467-0.198-0.0441Yes
38ZAKZAK
Entrez,  Source
-12544-0.209-0.0026Yes
39CDK8CDK8
Entrez,  Source
cyclin-dependent kinase 812650-0.2260.0405Yes
Table: GSEA details [plain text format]



Fig 2: PLX-4720_LINCS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: PLX-4720_LINCS: Random ES distribution   
Gene set null distribution of ES for PLX-4720_LINCS