| Dataset | NSCLC_collapsed_to_symbols.NSCLC.cls #SEN_versus_RES.NSCLC.cls #SEN_versus_RES_repos |
| Phenotype | NSCLC.cls#SEN_versus_RES_repos |
| Upregulated in class | 0 |
| GeneSet | TORIN1_LINCS |
| Enrichment Score (ES) | -0.3964265 |
| Normalized Enrichment Score (NES) | -1.1856058 |
| Nominal p-value | 0.20770878 |
| FDR q-value | 0.7774492 |
| FWER p-Value | 1.0 |

| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | TNK1 | TNK1 Entrez,  Source | tyrosine kinase, non-receptor, 1 | 1360 | 0.131 | -0.0476 | No |
| 2 | PIK3C2G | PIK3C2G Entrez,  Source | phosphoinositide-3-kinase, class 2, gamma polypeptide | 1498 | 0.123 | -0.0057 | No |
| 3 | INSR | INSR Entrez,  Source | insulin receptor | 1664 | 0.114 | 0.0302 | No |
| 4 | CSNK1D | CSNK1D Entrez,  Source | casein kinase 1, delta | 1851 | 0.105 | 0.0605 | No |
| 5 | ADCK4 | ADCK4 Entrez,  Source | aarF domain containing kinase 4 | 2715 | 0.077 | 0.0278 | No |
| 6 | LIMK2 | LIMK2 Entrez,  Source | LIM domain kinase 2 | 2799 | 0.076 | 0.0536 | No |
| 7 | FLT3 | FLT3 Entrez,  Source | fms-related tyrosine kinase 3 | 3403 | 0.063 | 0.0343 | No |
| 8 | LIMK1 | LIMK1 Entrez,  Source | LIM domain kinase 1 | 4468 | 0.045 | -0.0273 | No |
| 9 | PIK3CG | PIK3CG Entrez,  Source | phosphoinositide-3-kinase, catalytic, gamma polypeptide | 5329 | 0.033 | -0.0787 | No |
| 10 | CDK19 | 7263 | 0.004 | -0.2241 | No | ||
| 11 | KIT | KIT Entrez,  Source | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 8134 | -0.012 | -0.2852 | No |
| 12 | PTK2 | PTK2 Entrez,  Source | PTK2 protein tyrosine kinase 2 | 8356 | -0.016 | -0.2951 | No |
| 13 | PIK3CA | PIK3CA Entrez,  Source | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 8749 | -0.025 | -0.3143 | No |
| 14 | CDK2 | CDK2 Entrez,  Source | cyclin-dependent kinase 2 | 9409 | -0.040 | -0.3473 | No |
| 15 | CSNK2A2 | CSNK2A2 Entrez,  Source | casein kinase 2, alpha prime polypeptide | 9758 | -0.049 | -0.3529 | No |
| 16 | MAP4K4 | MAP4K4 Entrez,  Source | mitogen-activated protein kinase kinase kinase kinase 4 | 9922 | -0.055 | -0.3421 | No |
| 17 | TTK | TTK Entrez,  Source | TTK protein kinase | 9930 | -0.055 | -0.3194 | No |
| 18 | MTOR | 10944 | -0.091 | -0.3578 | Yes | ||
| 19 | RIPK1 | RIPK1 Entrez,  Source | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 11427 | -0.113 | -0.3463 | Yes |
| 20 | STK4 | STK4 Entrez,  Source | serine/threonine kinase 4 | 11518 | -0.118 | -0.3031 | Yes |
| 21 | MAP4K5 | MAP4K5 Entrez,  Source | mitogen-activated protein kinase kinase kinase kinase 5 | 11705 | -0.130 | -0.2622 | Yes |
| 22 | CDC42BPA | CDC42BPA Entrez,  Source | CDC42 binding protein kinase alpha (DMPK-like) | 11941 | -0.145 | -0.2187 | Yes |
| 23 | CDC42BPB | CDC42BPB Entrez,  Source | CDC42 binding protein kinase beta (DMPK-like) | 12053 | -0.154 | -0.1618 | Yes |
| 24 | MAPK6 | MAPK6 Entrez,  Source | mitogen-activated protein kinase 6 | 12214 | -0.168 | -0.1025 | Yes |
| 25 | MAP4K3 | MAP4K3 Entrez,  Source | mitogen-activated protein kinase kinase kinase kinase 3 | 12403 | -0.189 | -0.0366 | Yes |
| 26 | CDK8 | CDK8 Entrez,  Source | cyclin-dependent kinase 8 | 12650 | -0.226 | 0.0404 | Yes |

