DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class0
GeneSetJNK-9L_LINCS
Enrichment Score (ES)-0.3895872
Normalized Enrichment Score (NES)-1.3276349
Nominal p-value0.08274232
FDR q-value0.53824574
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: JNK-9L_LINCS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1METMET
Entrez,  Source
met proto-oncogene (hepatocyte growth factor receptor)4990.2590.0191No
2EPHB6EPHB6
Entrez,  Source
EPH receptor B67010.2150.0513No
3MAPK10MAPK10
Entrez,  Source
mitogen-activated protein kinase 1010690.1570.0580No
4PIP4K2C16760.1140.0369No
5RIOK3RIOK3
Entrez,  Source
RIO kinase 3 (yeast)19420.1010.0391No
6AAK1AAK1
Entrez,  Source
AP2 associated kinase 122120.0920.0389No
7JAK3JAK3
Entrez,  Source
Janus kinase 3 (a protein tyrosine kinase, leukocyte)24440.0840.0399No
8ADCK4ADCK4
Entrez,  Source
aarF domain containing kinase 427150.0770.0365No
9FLT3FLT3
Entrez,  Source
fms-related tyrosine kinase 334030.063-0.0020No
10CSF1RCSF1R
Entrez,  Source
colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog34540.0620.0078No
11CDKL5CDKL5
Entrez,  Source
cyclin-dependent kinase-like 543450.047-0.0496No
12CDKL2CDKL2
Entrez,  Source
cyclin-dependent kinase-like 2 (CDC2-related kinase)45480.044-0.0553No
13PIK3CGPIK3CG
Entrez,  Source
phosphoinositide-3-kinase, catalytic, gamma polypeptide53290.033-0.1074No
14MAPK4MAPK4
Entrez,  Source
mitogen-activated protein kinase 455850.029-0.1204No
15STK16STK16
Entrez,  Source
serine/threonine kinase 1657780.027-0.1291No
16IRAK1IRAK1
Entrez,  Source
interleukin-1 receptor-associated kinase 161790.021-0.1550No
17PIP4K2B65940.015-0.1832No
18MAPK8MAPK8
Entrez,  Source
mitogen-activated protein kinase 868290.011-0.1986No
19MAP4K2MAP4K2
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 268940.010-0.2013No
20CLK4CLK4
Entrez,  Source
CDC-like kinase 469350.010-0.2022No
21BMP2KBMP2K
Entrez,  Source
BMP2 inducible kinase70290.008-0.2075No
22CLK2CLK2
Entrez,  Source
CDC-like kinase 271810.005-0.2179No
23GSK3AGSK3A
Entrez,  Source
glycogen synthase kinase 3 alpha73580.002-0.2308No
24PDGFRBPDGFRB
Entrez,  Source
platelet-derived growth factor receptor, beta polypeptide7824-0.006-0.2650No
25MAPK9MAPK9
Entrez,  Source
mitogen-activated protein kinase 97830-0.006-0.2640No
26KITKIT
Entrez,  Source
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog8134-0.012-0.2845No
27MAP2K5MAP2K5
Entrez,  Source
mitogen-activated protein kinase kinase 58199-0.013-0.2864No
28DYRK1BDYRK1B
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B8200-0.013-0.2835No
29CDK168353-0.016-0.2915No
30STK11STK11
Entrez,  Source
serine/threonine kinase 119183-0.035-0.3470No
31TYK2TYK2
Entrez,  Source
tyrosine kinase 29438-0.041-0.3573No
32CSNK2A2CSNK2A2
Entrez,  Source
casein kinase 2, alpha prime polypeptide9758-0.049-0.3708No
33HIPK3HIPK3
Entrez,  Source
homeodomain interacting protein kinase 39770-0.050-0.3606No
34HIPK2HIPK2
Entrez,  Source
homeodomain interacting protein kinase 210151-0.061-0.3761Yes
35DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A10303-0.066-0.3731Yes
36CITCIT
Entrez,  Source
citron (rho-interacting, serine/threonine kinase 21)10420-0.070-0.3665Yes
37ICKICK
Entrez,  Source
intestinal cell (MAK-like) kinase10499-0.073-0.3564Yes
38JAK1JAK1
Entrez,  Source
Janus kinase 1 (a protein tyrosine kinase)10585-0.076-0.3462Yes
39CDK4CDK4
Entrez,  Source
cyclin-dependent kinase 410871-0.087-0.3486Yes
40GSK3BGSK3B
Entrez,  Source
glycogen synthase kinase 3 beta11131-0.100-0.3464Yes
41CDK7CDK7
Entrez,  Source
cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)11160-0.101-0.3263Yes
42RIPK1RIPK1
Entrez,  Source
receptor (TNFRSF)-interacting serine-threonine kinase 111427-0.113-0.3215Yes
43JAK2JAK2
Entrez,  Source
Janus kinase 2 (a protein tyrosine kinase)11530-0.119-0.3030Yes
44CDK9CDK9
Entrez,  Source
cyclin-dependent kinase 9 (CDC2-related kinase)11631-0.125-0.2830Yes
45SLKSLK
Entrez,  Source
STE20-like kinase (yeast)11672-0.128-0.2579Yes
46NEK3NEK3
Entrez,  Source
NIMA (never in mitosis gene a)-related kinase 311797-0.135-0.2374Yes
47HIPK1HIPK1
Entrez,  Source
homeodomain interacting protein kinase 111798-0.135-0.2075Yes
48MAP2K4MAP2K4
Entrez,  Source
mitogen-activated protein kinase kinase 411811-0.136-0.1783Yes
49CSNK2A1CSNK2A1
Entrez,  Source
casein kinase 2, alpha 1 polypeptide11861-0.139-0.1513Yes
50PDGFRAPDGFRA
Entrez,  Source
platelet-derived growth factor receptor, alpha polypeptide12211-0.168-0.1408Yes
51MAPK6MAPK6
Entrez,  Source
mitogen-activated protein kinase 612214-0.168-0.1038Yes
52MAP4K3MAP4K3
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 312403-0.189-0.0764Yes
53IRAK3IRAK3
Entrez,  Source
interleukin-1 receptor-associated kinase 312451-0.196-0.0368Yes
54RIOK2RIOK2
Entrez,  Source
RIO kinase 2 (yeast)12467-0.1980.0057Yes
55MAP3K7MAP3K7
Entrez,  Source
mitogen-activated protein kinase kinase kinase 712613-0.2210.0433Yes
Table: GSEA details [plain text format]



Fig 2: JNK-9L_LINCS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: JNK-9L_LINCS: Random ES distribution   
Gene set null distribution of ES for JNK-9L_LINCS