DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class1
GeneSetCEP-701_KINOME SCAN
Enrichment Score (ES)0.27050817
Normalized Enrichment Score (NES)1.0766675
Nominal p-value0.28834355
FDR q-value0.7631226
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: CEP-701_KINOME SCAN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1DAPK1DAPK1
Entrez,  Source
death-associated protein kinase 1880.5570.0163Yes
2EPHA1EPHA1
Entrez,  Source
EPH receptor A1940.5450.0385Yes
3RIPK4RIPK4
Entrez,  Source
receptor-interacting serine-threonine kinase 4950.5440.0611Yes
4FGFR3FGFR3
Entrez,  Source
fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)1530.4650.0760Yes
5PAK6PAK6
Entrez,  Source
p21(CDKN1A)-activated kinase 61580.4590.0948Yes
6FGFR2FGFR2
Entrez,  Source
ffer syndrome, Jackson-Weiss syndrome)2100.4060.1076Yes
7DDR1DDR1
Entrez,  Source
discoidin domain receptor family, member 12120.4040.1243Yes
8FRKFRK
Entrez,  Source
fyn-related kinase2960.3430.1321Yes
9PRKCDPRKCD
Entrez,  Source
protein kinase C, delta3060.3370.1454Yes
10MST43180.3310.1583Yes
11PRKCHPRKCH
Entrez,  Source
protein kinase C, eta3560.3090.1682Yes
12SYKSYK
Entrez,  Source
spleen tyrosine kinase4710.2680.1706Yes
13METMET
Entrez,  Source
met proto-oncogene (hepatocyte growth factor receptor)4990.2590.1792Yes
14ROS1ROS1
Entrez,  Source
v-ros UR2 sarcoma virus oncogene homolog 1 (avian)5050.2580.1895Yes
15IKBKBIKBKB
Entrez,  Source
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta5530.2450.1960Yes
16RPS6KA2RPS6KA2
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 25900.2370.2031Yes
17MAP3K13MAP3K13
Entrez,  Source
mitogen-activated protein kinase kinase kinase 136240.2300.2101Yes
18EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)6250.2300.2196Yes
19CDK146590.2220.2263Yes
20PAK1PAK1
Entrez,  Source
p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)6740.2190.2343Yes
21EPHB6EPHB6
Entrez,  Source
EPH receptor B67010.2150.2412Yes
22MAP3K6MAP3K6
Entrez,  Source
mitogen-activated protein kinase kinase kinase 68990.1800.2334Yes
23TAOK3TAOK3
Entrez,  Source
TAO kinase 39710.1700.2350Yes
24TXKTXK
Entrez,  Source
TXK tyrosine kinase10450.1600.2360Yes
25MAPK10MAPK10
Entrez,  Source
mitogen-activated protein kinase 1010690.1570.2407Yes
26TNIKTNIK
Entrez,  Source
TRAF2 and NCK interacting kinase11970.1450.2369Yes
27DYRK2DYRK2
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 212300.1420.2404Yes
28LCKLCK
Entrez,  Source
lymphocyte-specific protein tyrosine kinase13100.1360.2399Yes
29GAKGAK
Entrez,  Source
cyclin G associated kinase13400.1330.2432Yes
30TNK1TNK1
Entrez,  Source
tyrosine kinase, non-receptor, 113600.1310.2472Yes
31CAMK1DCAMK1D
Entrez,  Source
calcium/calmodulin-dependent protein kinase ID13870.1290.2505Yes
32EPHA7EPHA7
Entrez,  Source
EPH receptor A714120.1280.2540Yes
33PIK3C2GPIK3C2G
Entrez,  Source
phosphoinositide-3-kinase, class 2, gamma polypeptide14980.1230.2525Yes
34STK3STK3
Entrez,  Source
serine/threonine kinase 3 (STE20 homolog, yeast)15530.1200.2533Yes
35STK17BSTK17B
Entrez,  Source
serine/threonine kinase 17b (apoptosis-inducing)15540.1190.2583Yes
36RPS6KA1RPS6KA1
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 116860.1130.2528Yes
37MAP3K9MAP3K9
Entrez,  Source
mitogen-activated protein kinase kinase kinase 916990.1120.2566Yes
38NTRK2NTRK2
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 217040.1120.2609Yes
39CAMK2ACAMK2A
Entrez,  Source
calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha18010.1070.2579Yes
40CAMK2GCAMK2G
Entrez,  Source
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma18110.1070.2617Yes
41DAPK2DAPK2
Entrez,  Source
death-associated protein kinase 218380.1050.2640Yes
42TESK1TESK1
Entrez,  Source
testis-specific kinase 118550.1050.2671Yes
43RIOK3RIOK3
Entrez,  Source
RIO kinase 3 (yeast)19420.1010.2647Yes
44LYNLYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog19740.1000.2664Yes
45CASKCASK
Entrez,  Source
calcium/calmodulin-dependent serine protein kinase (MAGUK family)20070.0990.2680Yes
46PTK2BPTK2B
Entrez,  Source
PTK2B protein tyrosine kinase 2 beta20420.0980.2694Yes
47MAP3K5MAP3K5
Entrez,  Source
mitogen-activated protein kinase kinase kinase 521470.0940.2653Yes
48MARK1MARK1
Entrez,  Source
MAP/microtubule affinity-regulating kinase 121590.0930.2683Yes
49AAK1AAK1
Entrez,  Source
AP2 associated kinase 122120.0920.2681Yes
50ULK2ULK2
Entrez,  Source
unc-51-like kinase 2 (C. elegans)22440.0910.2695Yes
51MAP3K11MAP3K11
Entrez,  Source
mitogen-activated protein kinase kinase kinase 1122950.0890.2693Yes
52TIE1TIE1
Entrez,  Source
tyrosine kinase with immunoglobulin-like and EGF-like domains 123280.0880.2705Yes
53JAK3JAK3
Entrez,  Source
Janus kinase 3 (a protein tyrosine kinase, leukocyte)24440.0840.2651No
54MERTKMERTK
Entrez,  Source
c-mer proto-oncogene tyrosine kinase25220.0820.2626No
55TAOK1TAOK1
Entrez,  Source
TAO kinase 125520.0820.2637No
56RPS6KA5RPS6KA5
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 526100.0800.2627No
57MAP4K1MAP4K1
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 128490.0740.2473No
58EPHA3EPHA3
Entrez,  Source
EPH receptor A328700.0740.2489No
59STK38STK38
Entrez,  Source
serine/threonine kinase 3828780.0730.2514No
60MKNK1MKNK1
Entrez,  Source
MAP kinase interacting serine/threonine kinase 129070.0730.2522No
61PIM2PIM2
Entrez,  Source
pim-2 oncogene29560.0710.2515No
62TNK2TNK2
Entrez,  Source
tyrosine kinase, non-receptor, 230050.0700.2507No
63YES1YES1
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 130360.0700.2512No
64CSKCSK
Entrez,  Source
c-src tyrosine kinase30690.0690.2516No
65MINK1MINK1
Entrez,  Source
misshapen-like kinase 1 (zebrafish)30800.0690.2537No
66KDRKDR
Entrez,  Source
kinase insert domain receptor (a type III receptor tyrosine kinase)31460.0680.2515No
67FLT3FLT3
Entrez,  Source
fms-related tyrosine kinase 334030.0630.2343No
68BLKBLK
Entrez,  Source
B lymphoid tyrosine kinase34190.0620.2358No
69TSSK1B34450.0620.2364No
70CSF1RCSF1R
Entrez,  Source
colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog34540.0620.2383No
71MYO3AMYO3A
Entrez,  Source
myosin IIIA37350.0570.2191No
72MARK2MARK2
Entrez,  Source
MAP/microtubule affinity-regulating kinase 238340.0550.2138No
73PRKD2PRKD2
Entrez,  Source
protein kinase D239000.0540.2110No
74PRKG2PRKG2
Entrez,  Source
protein kinase, cGMP-dependent, type II40210.0520.2039No
75ALKALK
Entrez,  Source
anaplastic lymphoma kinase (Ki-1)40730.0510.2020No
76PIM1PIM1
Entrez,  Source
pim-1 oncogene41360.0500.1993No
77FGRFGR
Entrez,  Source
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog41930.0490.1971No
78CAMK2BCAMK2B
Entrez,  Source
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta42130.0490.1976No
79ACVR1BACVR1B
Entrez,  Source
activin A receptor, type IB43280.0470.1908No
80CDKL5CDKL5
Entrez,  Source
cyclin-dependent kinase-like 543450.0470.1915No
81AURKCAURKC
Entrez,  Source
aurora kinase C44130.0460.1882No
82CAMK1GCAMK1G
Entrez,  Source
calcium/calmodulin-dependent protein kinase IG45030.0450.1832No
83CDKL2CDKL2
Entrez,  Source
cyclin-dependent kinase-like 2 (CDC2-related kinase)45480.0440.1816No
84HUNKHUNK
Entrez,  Source
hormonally upregulated Neu-associated kinase46450.0430.1760No
85RPS6KA6RPS6KA6
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 646850.0420.1747No
86PHKG2PHKG2
Entrez,  Source
phosphorylase kinase, gamma 2 (testis)47920.0400.1682No
87BMXBMX
Entrez,  Source
BMX non-receptor tyrosine kinase48260.0400.1673No
88EPHA2EPHA2
Entrez,  Source
EPH receptor A248800.0390.1648No
89FLT1FLT1
Entrez,  Source
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)48820.0390.1664No
90FLT4FLT4
Entrez,  Source
fms-related tyrosine kinase 448980.0390.1668No
91GRK1GRK1
Entrez,  Source
G protein-coupled receptor kinase 149070.0390.1678No
92PRKG1PRKG1
Entrez,  Source
protein kinase, cGMP-dependent, type I49360.0380.1672No
93PAK4PAK4
Entrez,  Source
p21(CDKN1A)-activated kinase 450140.0370.1628No
94ULK1ULK1
Entrez,  Source
unc-51-like kinase 1 (C. elegans)51570.0350.1533No
95ACVR1ACVR1
Entrez,  Source
activin A receptor, type I52300.0340.1491No
96PIK3CGPIK3CG
Entrez,  Source
phosphoinositide-3-kinase, catalytic, gamma polypeptide53290.0330.1429No
97MAST1MAST1
Entrez,  Source
microtubule associated serine/threonine kinase 154360.0320.1361No
98PDPK1PDPK1
Entrez,  Source
3-phosphoinositide dependent protein kinase-155490.0300.1286No
99STK24STK24
Entrez,  Source
serine/threonine kinase 24 (STE20 homolog, yeast)55870.0290.1270No
100BTKBTK
Entrez,  Source
Bruton agammaglobulinemia tyrosine kinase56280.0290.1251No
101STK16STK16
Entrez,  Source
serine/threonine kinase 1657780.0270.1147No
102SRPK3SRPK3
Entrez,  Source
SFRS protein kinase 358600.0260.1095No
103PAK7PAK7
Entrez,  Source
p21(CDKN1A)-activated kinase 758810.0250.1090No
104MAP3K3MAP3K3
Entrez,  Source
mitogen-activated protein kinase kinase kinase 359210.0250.1070No
105PRKXPRKX
Entrez,  Source
protein kinase, X-linked59930.0240.1025No
106CDK1360620.0230.0982No
107NTRK1NTRK1
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 160970.0220.0965No
108FESFES
Entrez,  Source
feline sarcoma oncogene61260.0220.0952No
109IRAK1IRAK1
Entrez,  Source
interleukin-1 receptor-associated kinase 161790.0210.0921No
110PHKG1PHKG1
Entrez,  Source
phosphorylase kinase, gamma 1 (muscle)62450.0200.0879No
111AURKAAURKA
Entrez,  Source
aurora kinase A64270.0170.0746No
112RETRET
Entrez,  Source
ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)64710.0160.0719No
113EIF2AK2EIF2AK2
Entrez,  Source
eukaryotic translation initiation factor 2-alpha kinase 264890.0160.0713No
114MAP3K10MAP3K10
Entrez,  Source
mitogen-activated protein kinase kinase kinase 1065490.0150.0674No
115PIP4K2B65940.0150.0646No
116BMPR1BBMPR1B
Entrez,  Source
bone morphogenetic protein receptor, type IB67770.0120.0510No
117PKN1PKN1
Entrez,  Source
protein kinase N167830.0120.0511No
118GRK4GRK4
Entrez,  Source
G protein-coupled receptor kinase 467880.0120.0513No
119MAPK8MAPK8
Entrez,  Source
mitogen-activated protein kinase 868290.0110.0487No
120MAP4K2MAP4K2
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 268940.0100.0441No
121CLK4CLK4
Entrez,  Source
CDC-like kinase 469350.0100.0415No
122BMP2KBMP2K
Entrez,  Source
BMP2 inducible kinase70290.0080.0346No
123TEKTEK
Entrez,  Source
TEK tyrosine kinase, endothelial (venous malformations, multiple cutaneous and mucosal)70350.0080.0345No
124TGFBR2TGFBR2
Entrez,  Source
transforming growth factor, beta receptor II (70/80kDa)71030.0070.0296No
125CLK2CLK2
Entrez,  Source
CDC-like kinase 271810.0050.0239No
126IKBKEIKBKE
Entrez,  Source
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon72160.0040.0215No
127ITKITK
Entrez,  Source
IL2-inducible T-cell kinase72200.0040.0214No
128PRKAA2PRKAA2
Entrez,  Source
protein kinase, AMP-activated, alpha 2 catalytic subunit74180.0010.0062No
129CDK5CDK5
Entrez,  Source
cyclin-dependent kinase 574320.0010.0053No
130SIK274350.0010.0051No
131PI4KB7697-0.003-0.0149No
132SIK37726-0.004-0.0169No
133MAP2K3MAP2K3
Entrez,  Source
mitogen-activated protein kinase kinase 37798-0.005-0.0222No
134PDGFRBPDGFRB
Entrez,  Source
platelet-derived growth factor receptor, beta polypeptide7824-0.006-0.0238No
135MAPK9MAPK9
Entrez,  Source
mitogen-activated protein kinase 97830-0.006-0.0240No
136MKNK2MKNK2
Entrez,  Source
MAP kinase interacting serine/threonine kinase 27841-0.006-0.0245No
137MAP2K1MAP2K1
Entrez,  Source
mitogen-activated protein kinase kinase 17939-0.008-0.0317No
138MATKMATK
Entrez,  Source
megakaryocyte-associated tyrosine kinase7989-0.009-0.0351No
139MELKMELK
Entrez,  Source
maternal embryonic leucine zipper kinase8047-0.010-0.0391No
140TAOK2TAOK2
Entrez,  Source
TAO kinase 28059-0.010-0.0395No
141PRKACAPRKACA
Entrez,  Source
protein kinase, cAMP-dependent, catalytic, alpha8112-0.011-0.0431No
142KITKIT
Entrez,  Source
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog8134-0.012-0.0442No
143LTKLTK
Entrez,  Source
leukocyte tyrosine kinase8158-0.012-0.0455No
144RPS6KA4RPS6KA4
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 48181-0.013-0.0466No
145MAP2K5MAP2K5
Entrez,  Source
mitogen-activated protein kinase kinase 58199-0.013-0.0474No
146DYRK1BDYRK1B
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B8200-0.013-0.0469No
147CDKL3CDKL3
Entrez,  Source
cyclin-dependent kinase-like 38249-0.014-0.0500No
148MARK4MARK4
Entrez,  Source
MAP/microtubule affinity-regulating kinase 48259-0.014-0.0501No
149DMPKDMPK
Entrez,  Source
dystrophia myotonica-protein kinase8344-0.016-0.0559No
150CDK168353-0.016-0.0559No
151CDK3CDK3
Entrez,  Source
cyclin-dependent kinase 38440-0.018-0.0618No
152NTRK3NTRK3
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 38500-0.019-0.0655No
153STK25STK25
Entrez,  Source
serine/threonine kinase 25 (STE20 homolog, yeast)8561-0.021-0.0693No
154ROCK1ROCK1
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 18741-0.025-0.0821No
155PIK3CAPIK3CA
Entrez,  Source
phosphoinositide-3-kinase, catalytic, alpha polypeptide8749-0.025-0.0816No
156AURKBAURKB
Entrez,  Source
aurora kinase B8856-0.027-0.0887No
157ZAP70ZAP70
Entrez,  Source
zeta-chain (TCR) associated protein kinase 70kDa8954-0.030-0.0949No
158CDKL1CDKL1
Entrez,  Source
cyclin-dependent kinase-like 1 (CDC2-related kinase)8993-0.031-0.0966No
159IRAK4IRAK4
Entrez,  Source
interleukin-1 receptor-associated kinase 48996-0.031-0.0955No
160STK11STK11
Entrez,  Source
serine/threonine kinase 119183-0.035-0.1084No
161MAPKAPK2MAPKAPK2
Entrez,  Source
mitogen-activated protein kinase-activated protein kinase 29187-0.035-0.1072No
162ERN1ERN1
Entrez,  Source
endoplasmic reticulum to nucleus signalling 19341-0.039-0.1174No
163CDK2CDK2
Entrez,  Source
cyclin-dependent kinase 29409-0.040-0.1209No
164TYK2TYK2
Entrez,  Source
tyrosine kinase 29438-0.041-0.1214No
165PAK3PAK3
Entrez,  Source
p21 (CDKN1A)-activated kinase 39490-0.042-0.1236No
166CSNK2A2CSNK2A2
Entrez,  Source
casein kinase 2, alpha prime polypeptide9758-0.049-0.1422No
167HIPK3HIPK3
Entrez,  Source
homeodomain interacting protein kinase 39770-0.050-0.1410No
168PRKD1PRKD1
Entrez,  Source
protein kinase D19827-0.052-0.1431No
169MAP2K7MAP2K7
Entrez,  Source
mitogen-activated protein kinase kinase 79831-0.052-0.1412No
170MAP4K4MAP4K4
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 49922-0.055-0.1459No
171TTKTTK
Entrez,  Source
TTK protein kinase9930-0.055-0.1442No
172HCKHCK
Entrez,  Source
hemopoietic cell kinase9981-0.056-0.1457No
173PLK2PLK2
Entrez,  Source
polo-like kinase 2 (Drosophila)9994-0.057-0.1443No
174STK17ASTK17A
Entrez,  Source
serine/threonine kinase 17a (apoptosis-inducing)10017-0.057-0.1436No
175LATS1LATS1
Entrez,  Source
LATS, large tumor suppressor, homolog 1 (Drosophila)10025-0.057-0.1418No
176CHEK2CHEK2
Entrez,  Source
CHK2 checkpoint homolog (S. pombe)10102-0.059-0.1452No
177HIPK2HIPK2
Entrez,  Source
homeodomain interacting protein kinase 210151-0.061-0.1464No
178DDR2DDR2
Entrez,  Source
discoidin domain receptor family, member 210235-0.064-0.1502No
179DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A10303-0.066-0.1526No
180MARK3MARK3
Entrez,  Source
MAP/microtubule affinity-regulating kinase 310374-0.068-0.1552No
181CITCIT
Entrez,  Source
citron (rho-interacting, serine/threonine kinase 21)10420-0.070-0.1558No
182RPS6KA3RPS6KA3
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 310427-0.070-0.1533No
183PLK1PLK1
Entrez,  Source
polo-like kinase 1 (Drosophila)10440-0.071-0.1513No
184ICKICK
Entrez,  Source
intestinal cell (MAK-like) kinase10499-0.073-0.1528No
185PLK4PLK4
Entrez,  Source
polo-like kinase 4 (Drosophila)10581-0.075-0.1559No
186JAK1JAK1
Entrez,  Source
Janus kinase 1 (a protein tyrosine kinase)10585-0.076-0.1530No
187RPS6KB1RPS6KB1
Entrez,  Source
ribosomal protein S6 kinase, 70kDa, polypeptide 110717-0.081-0.1598No
188CAMKK2CAMKK2
Entrez,  Source
calcium/calmodulin-dependent protein kinase kinase 2, beta10729-0.081-0.1573No
189TBK1TBK1
Entrez,  Source
TANK-binding kinase 110732-0.082-0.1540No
190BRSK2BRSK2
Entrez,  Source
BR serine/threonine kinase 210749-0.082-0.1519No
191SRCSRC
Entrez,  Source
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)10776-0.083-0.1504No
192PIP5K1APIP5K1A
Entrez,  Source
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha10780-0.083-0.1472No
193CHEK1CHEK1
Entrez,  Source
CHK1 checkpoint homolog (S. pombe)10792-0.084-0.1445No
194PRKCEPRKCE
Entrez,  Source
protein kinase C, epsilon10801-0.084-0.1417No
195PAK2PAK2
Entrez,  Source
p21 (CDKN1A)-activated kinase 210809-0.085-0.1387No
196CDK4CDK4
Entrez,  Source
cyclin-dependent kinase 410871-0.087-0.1398No
197PRKAA1PRKAA1
Entrez,  Source
protein kinase, AMP-activated, alpha 1 catalytic subunit10906-0.089-0.1387No
198PRKCQPRKCQ
Entrez,  Source
protein kinase C, theta10961-0.092-0.1391No
199MAPKAPK5MAPKAPK5
Entrez,  Source
mitogen-activated protein kinase-activated protein kinase 510962-0.092-0.1353No
200NLKNLK
Entrez,  Source
nemo-like kinase10979-0.093-0.1327No
201NUAK1NUAK1
Entrez,  Source
NUAK family, SNF1-like kinase, 111032-0.095-0.1328No
202DAPK3DAPK3
Entrez,  Source
death-associated protein kinase 311066-0.096-0.1313No
203SRPK1SRPK1
Entrez,  Source
SFRS protein kinase 111068-0.096-0.1274No
204CDK7CDK7
Entrez,  Source
cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)11160-0.101-0.1303No
205PRKACBPRKACB
Entrez,  Source
protein kinase, cAMP-dependent, catalytic, beta11179-0.102-0.1274No
206STK10STK10
Entrez,  Source
serine/threonine kinase 1011218-0.103-0.1261No
207MYLKMYLK
Entrez,  Source
myosin, light chain kinase11255-0.105-0.1245No
208RIPK2RIPK2
Entrez,  Source
receptor-interacting serine-threonine kinase 211349-0.110-0.1271No
209FERFER
Entrez,  Source
fer (fps/fes related) tyrosine kinase (phosphoprotein NCP94)11371-0.111-0.1242No
210STK38LSTK38L
Entrez,  Source
serine/threonine kinase 38 like11441-0.114-0.1248No
211SRPK2SRPK2
Entrez,  Source
SFRS protein kinase 211496-0.117-0.1241No
212STK4STK4
Entrez,  Source
serine/threonine kinase 411518-0.118-0.1208No
213JAK2JAK2
Entrez,  Source
Janus kinase 2 (a protein tyrosine kinase)11530-0.119-0.1167No
214TYRO3TYRO3
Entrez,  Source
TYRO3 protein tyrosine kinase11601-0.123-0.1170No
215TLK2TLK2
Entrez,  Source
tousled-like kinase 211621-0.124-0.1133No
216CDK9CDK9
Entrez,  Source
cyclin-dependent kinase 9 (CDC2-related kinase)11631-0.125-0.1088No
217SLKSLK
Entrez,  Source
STE20-like kinase (yeast)11672-0.128-0.1066No
218MAP4K5MAP4K5
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 511705-0.130-0.1037No
219FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES11767-0.133-0.1029No
220HIPK1HIPK1
Entrez,  Source
homeodomain interacting protein kinase 111798-0.135-0.0996No
221MAP2K4MAP2K4
Entrez,  Source
mitogen-activated protein kinase kinase 411811-0.136-0.0949No
222PRPF4BPRPF4B
Entrez,  Source
PRP4 pre-mRNA processing factor 4 homolog B (yeast)11856-0.139-0.0925No
223MAP2K2MAP2K2
Entrez,  Source
mitogen-activated protein kinase kinase 211895-0.142-0.0896No
224MAP2K6MAP2K6
Entrez,  Source
mitogen-activated protein kinase kinase 611934-0.144-0.0865No
225ROCK2ROCK2
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 212033-0.152-0.0878No
226CDC42BPBCDC42BPB
Entrez,  Source
CDC42 binding protein kinase beta (DMPK-like)12053-0.154-0.0829No
227CAMK1CAMK1
Entrez,  Source
calcium/calmodulin-dependent protein kinase I12150-0.162-0.0836No
228MAP3K2MAP3K2
Entrez,  Source
mitogen-activated protein kinase kinase kinase 212210-0.168-0.0812No
229PDGFRAPDGFRA
Entrez,  Source
platelet-derived growth factor receptor, alpha polypeptide12211-0.168-0.0742No
230PKN2PKN2
Entrez,  Source
protein kinase N212286-0.175-0.0726No
231SIK112319-0.179-0.0677No
232MAP3K12MAP3K12
Entrez,  Source
mitogen-activated protein kinase kinase kinase 1212384-0.186-0.0649No
233MAP4K3MAP4K3
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 312403-0.189-0.0585No
234BMPR1ABMPR1A
Entrez,  Source
bone morphogenetic protein receptor, type IA12438-0.194-0.0530No
235TGFBR1TGFBR1
Entrez,  Source
transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa)12447-0.195-0.0456No
236IRAK3IRAK3
Entrez,  Source
interleukin-1 receptor-associated kinase 312451-0.196-0.0377No
237ABL1ABL1
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 112463-0.197-0.0303No
238TLK1TLK1
Entrez,  Source
tousled-like kinase 112558-0.210-0.0289No
239CDK1712578-0.213-0.0215No
240MAP3K7MAP3K7
Entrez,  Source
mitogen-activated protein kinase kinase kinase 712613-0.221-0.0150No
241AXLAXL
Entrez,  Source
AXL receptor tyrosine kinase12789-0.257-0.0178No
242CHUKCHUK
Entrez,  Source
conserved helix-loop-helix ubiquitous kinase12978-0.325-0.0189No
243PRKD3PRKD3
Entrez,  Source
protein kinase D313008-0.345-0.0068No
244FGFR1FGFR1
Entrez,  Source
fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)13121-0.4860.0047No
Table: GSEA details [plain text format]



Fig 2: CEP-701_KINOME SCAN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: CEP-701_KINOME SCAN: Random ES distribution   
Gene set null distribution of ES for CEP-701_KINOME SCAN