DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class0
GeneSetKINOME_3629_ROCHE
Enrichment Score (ES)-0.24690904
Normalized Enrichment Score (NES)-0.8908484
Nominal p-value0.6526055
FDR q-value0.8831382
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: KINOME_3629_ROCHE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1MST1RMST1R
Entrez,  Source
macrophage stimulating 1 receptor (c-met-related tyrosine kinase)540.6360.0857No
2PRKCDPRKCD
Entrez,  Source
protein kinase C, delta3060.3370.1140No
3SYKSYK
Entrez,  Source
spleen tyrosine kinase4710.2680.1394No
4ROS1ROS1
Entrez,  Source
v-ros UR2 sarcoma virus oncogene homolog 1 (avian)5050.2580.1732No
5PAK1PAK1
Entrez,  Source
p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)6740.2190.1913No
6CAMK1DCAMK1D
Entrez,  Source
calcium/calmodulin-dependent protein kinase ID13870.1290.1552No
7STK3STK3
Entrez,  Source
serine/threonine kinase 3 (STE20 homolog, yeast)15530.1200.1594No
8INSRINSR
Entrez,  Source
insulin receptor16640.1140.1672No
9NTRK2NTRK2
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 217040.1120.1800No
10CAMK2ACAMK2A
Entrez,  Source
calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha18010.1070.1878No
11LYNLYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog19740.1000.1887No
12JAK3JAK3
Entrez,  Source
Janus kinase 3 (a protein tyrosine kinase, leukocyte)24440.0840.1649No
13TAOK1TAOK1
Entrez,  Source
TAO kinase 125520.0820.1683No
14PIM2PIM2
Entrez,  Source
pim-2 oncogene29560.0710.1476No
15TNK2TNK2
Entrez,  Source
tyrosine kinase, non-receptor, 230050.0700.1538No
16KDRKDR
Entrez,  Source
kinase insert domain receptor (a type III receptor tyrosine kinase)31460.0680.1527No
17FLT3FLT3
Entrez,  Source
fms-related tyrosine kinase 334030.0630.1420No
18BLKBLK
Entrez,  Source
B lymphoid tyrosine kinase34190.0620.1496No
19CSF1RCSF1R
Entrez,  Source
colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog34540.0620.1558No
20MARK2MARK2
Entrez,  Source
MAP/microtubule affinity-regulating kinase 238340.0550.1346No
21PRKD2PRKD2
Entrez,  Source
protein kinase D239000.0540.1373No
22ALKALK
Entrez,  Source
anaplastic lymphoma kinase (Ki-1)40730.0510.1314No
23FLT1FLT1
Entrez,  Source
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)48820.0390.0752No
24FLT4FLT4
Entrez,  Source
fms-related tyrosine kinase 448980.0390.0796No
25PAK4PAK4
Entrez,  Source
p21(CDKN1A)-activated kinase 450140.0370.0760No
26PDPK1PDPK1
Entrez,  Source
3-phosphoinositide dependent protein kinase-155490.0300.0395No
27PRKXPRKX
Entrez,  Source
protein kinase, X-linked59930.0240.0091No
28NTRK1NTRK1
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 160970.0220.0043No
29AURKAAURKA
Entrez,  Source
aurora kinase A64270.017-0.0184No
30RETRET
Entrez,  Source
ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)64710.016-0.0194No
31MAP3K10MAP3K10
Entrez,  Source
mitogen-activated protein kinase kinase kinase 1065490.015-0.0231No
32MAP4K2MAP4K2
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 268940.010-0.0479No
33CLK4CLK4
Entrez,  Source
CDC-like kinase 469350.010-0.0496No
34IKBKEIKBKE
Entrez,  Source
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon72160.004-0.0704No
35ITKITK
Entrez,  Source
IL2-inducible T-cell kinase72200.004-0.0700No
36AKT1AKT1
Entrez,  Source
v-akt murine thymoma viral oncogene homolog 173870.002-0.0824No
37CDK5CDK5
Entrez,  Source
cyclin-dependent kinase 574320.001-0.0856No
38SIK274350.001-0.0856No
39PRKCGPRKCG
Entrez,  Source
protein kinase C, gamma74490.001-0.0866No
40PDGFRBPDGFRB
Entrez,  Source
platelet-derived growth factor receptor, beta polypeptide7824-0.006-0.1143No
41MAP2K1MAP2K1
Entrez,  Source
mitogen-activated protein kinase kinase 17939-0.008-0.1218No
42MELKMELK
Entrez,  Source
maternal embryonic leucine zipper kinase8047-0.010-0.1286No
43PRKACAPRKACA
Entrez,  Source
protein kinase, cAMP-dependent, catalytic, alpha8112-0.011-0.1319No
44LTKLTK
Entrez,  Source
leukocyte tyrosine kinase8158-0.012-0.1336No
45DYRK1BDYRK1B
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B8200-0.013-0.1349No
46MARK4MARK4
Entrez,  Source
MAP/microtubule affinity-regulating kinase 48259-0.014-0.1373No
47CDK18390-0.017-0.1448No
48NTRK3NTRK3
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 38500-0.019-0.1504No
49ROCK1ROCK1
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 18741-0.025-0.1652No
50AURKBAURKB
Entrez,  Source
aurora kinase B8856-0.027-0.1700No
51IRAK4IRAK4
Entrez,  Source
interleukin-1 receptor-associated kinase 48996-0.031-0.1763No
52MAP4K4MAP4K4
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 49922-0.055-0.2392Yes
53HCKHCK
Entrez,  Source
hemopoietic cell kinase9981-0.056-0.2357Yes
54STK17ASTK17A
Entrez,  Source
serine/threonine kinase 17a (apoptosis-inducing)10017-0.057-0.2303Yes
55CHEK2CHEK2
Entrez,  Source
CHK2 checkpoint homolog (S. pombe)10102-0.059-0.2284Yes
56DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A10303-0.066-0.2343Yes
57MARK3MARK3
Entrez,  Source
MAP/microtubule affinity-regulating kinase 310374-0.068-0.2301Yes
58RPS6KA3RPS6KA3
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 310427-0.070-0.2241Yes
59PLK4PLK4
Entrez,  Source
polo-like kinase 4 (Drosophila)10581-0.075-0.2251Yes
60RPS6KB1RPS6KB1
Entrez,  Source
ribosomal protein S6 kinase, 70kDa, polypeptide 110717-0.081-0.2240Yes
61CAMKK2CAMKK2
Entrez,  Source
calcium/calmodulin-dependent protein kinase kinase 2, beta10729-0.081-0.2134Yes
62TBK1TBK1
Entrez,  Source
TANK-binding kinase 110732-0.082-0.2020Yes
63CHEK1CHEK1
Entrez,  Source
CHK1 checkpoint homolog (S. pombe)10792-0.084-0.1946Yes
64PRKAA1PRKAA1
Entrez,  Source
protein kinase, AMP-activated, alpha 1 catalytic subunit10906-0.089-0.1907Yes
65PRKCQPRKCQ
Entrez,  Source
protein kinase C, theta10961-0.092-0.1819Yes
66DAPK3DAPK3
Entrez,  Source
death-associated protein kinase 311066-0.096-0.1762Yes
67FERFER
Entrez,  Source
fer (fps/fes related) tyrosine kinase (phosphoprotein NCP94)11371-0.111-0.1838Yes
68JAK2JAK2
Entrez,  Source
Janus kinase 2 (a protein tyrosine kinase)11530-0.119-0.1791Yes
69TYRO3TYRO3
Entrez,  Source
TYRO3 protein tyrosine kinase11601-0.123-0.1671Yes
70CDK9CDK9
Entrez,  Source
cyclin-dependent kinase 9 (CDC2-related kinase)11631-0.125-0.1516Yes
71MAP4K5MAP4K5
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 511705-0.130-0.1389Yes
72CDC42BPACDC42BPA
Entrez,  Source
CDC42 binding protein kinase alpha (DMPK-like)11941-0.145-0.1364Yes
73ROCK2ROCK2
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 212033-0.152-0.1219Yes
74CAMK1CAMK1
Entrez,  Source
calcium/calmodulin-dependent protein kinase I12150-0.162-0.1079Yes
75PDGFRAPDGFRA
Entrez,  Source
platelet-derived growth factor receptor, alpha polypeptide12211-0.168-0.0888Yes
76PKN2PKN2
Entrez,  Source
protein kinase N212286-0.175-0.0697Yes
77AKT3AKT3
Entrez,  Source
v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)12533-0.207-0.0592Yes
78AKT2AKT2
Entrez,  Source
v-akt murine thymoma viral oncogene homolog 212829-0.271-0.0434Yes
79SGK113133-0.4980.0037Yes
Table: GSEA details [plain text format]



Fig 2: KINOME_3629_ROCHE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: KINOME_3629_ROCHE: Random ES distribution   
Gene set null distribution of ES for KINOME_3629_ROCHE