DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class1
GeneSetGSK-1838705A_KINOME SCAN
Enrichment Score (ES)0.35818827
Normalized Enrichment Score (NES)1.0602279
Nominal p-value0.38113207
FDR q-value0.79191464
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: GSK-1838705A_KINOME SCAN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1DAPK1DAPK1
Entrez,  Source
death-associated protein kinase 1880.5570.1654Yes
2ROS1ROS1
Entrez,  Source
v-ros UR2 sarcoma virus oncogene homolog 1 (avian)5050.2580.2134Yes
3EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)6250.2300.2755Yes
4MAPK10MAPK10
Entrez,  Source
mitogen-activated protein kinase 1010690.1570.2904Yes
5GAKGAK
Entrez,  Source
cyclin G associated kinase13400.1330.3110Yes
6INSRINSR
Entrez,  Source
insulin receptor16640.1140.3218Yes
7RPS6KA1RPS6KA1
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 116860.1130.3550Yes
8PTK2BPTK2B
Entrez,  Source
PTK2B protein tyrosine kinase 2 beta20420.0980.3582Yes
9TSSK1B34450.0620.2707No
10ALKALK
Entrez,  Source
anaplastic lymphoma kinase (Ki-1)40730.0510.2388No
11GRK1GRK1
Entrez,  Source
G protein-coupled receptor kinase 149070.0390.1875No
12INSRRINSRR
Entrez,  Source
insulin receptor-related receptor53320.0330.1654No
13FESFES
Entrez,  Source
feline sarcoma oncogene61260.0220.1117No
14CAMK4CAMK4
Entrez,  Source
calcium/calmodulin-dependent protein kinase IV63930.0170.0969No
15MAPK8MAPK8
Entrez,  Source
mitogen-activated protein kinase 868290.0110.0672No
16CLK4CLK4
Entrez,  Source
CDC-like kinase 469350.0100.0622No
17CLK2CLK2
Entrez,  Source
CDC-like kinase 271810.0050.0451No
18CSNK1ECSNK1E
Entrez,  Source
casein kinase 1, epsilon7742-0.0040.0039No
19MAP2K3MAP2K3
Entrez,  Source
mitogen-activated protein kinase kinase 37798-0.0050.0013No
20MAPK9MAPK9
Entrez,  Source
mitogen-activated protein kinase 97830-0.0060.0009No
21IGF1RIGF1R
Entrez,  Source
insulin-like growth factor 1 receptor7959-0.008-0.0063No
22LTKLTK
Entrez,  Source
leukocyte tyrosine kinase8158-0.012-0.0176No
23DYRK1BDYRK1B
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B8200-0.013-0.0166No
24PTK2PTK2
Entrez,  Source
PTK2 protein tyrosine kinase 28356-0.016-0.0233No
25PRKD1PRKD1
Entrez,  Source
protein kinase D19827-0.052-0.1192No
26TTKTTK
Entrez,  Source
TTK protein kinase9930-0.055-0.1101No
27CHEK2CHEK2
Entrez,  Source
CHK2 checkpoint homolog (S. pombe)10102-0.059-0.1047No
28RPS6KA3RPS6KA3
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 310427-0.070-0.1076No
29PLK1PLK1
Entrez,  Source
polo-like kinase 1 (Drosophila)10440-0.071-0.0866No
30MYLKMYLK
Entrez,  Source
myosin, light chain kinase11255-0.105-0.1161No
31FERFER
Entrez,  Source
fer (fps/fes related) tyrosine kinase (phosphoprotein NCP94)11371-0.111-0.0906No
32MAP2K4MAP2K4
Entrez,  Source
mitogen-activated protein kinase kinase 411811-0.136-0.0819No
33AXLAXL
Entrez,  Source
AXL receptor tyrosine kinase12789-0.257-0.0768No
34PRKD3PRKD3
Entrez,  Source
protein kinase D313008-0.3450.0132No
Table: GSEA details [plain text format]



Fig 2: GSK-1838705A_KINOME SCAN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: GSK-1838705A_KINOME SCAN: Random ES distribution   
Gene set null distribution of ES for GSK-1838705A_KINOME SCAN