| Dataset | NSCLC_collapsed_to_symbols.NSCLC.cls #SEN_versus_RES.NSCLC.cls #SEN_versus_RES_repos |
| Phenotype | NSCLC.cls#SEN_versus_RES_repos |
| Upregulated in class | 1 |
| GeneSet | NERATINIB_LINCS |
| Enrichment Score (ES) | 0.50443536 |
| Normalized Enrichment Score (NES) | 1.4224725 |
| Nominal p-value | 0.07194245 |
| FDR q-value | 0.6169691 |
| FWER p-Value | 0.998 |

| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ERBB3 | ERBB3 Entrez,  Source | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 12 | 1.034 | 0.2384 | Yes |
| 2 | ERBB2 | ERBB2 Entrez,  Source | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 100 | 0.537 | 0.3561 | Yes |
| 3 | MST4 | 318 | 0.331 | 0.4162 | Yes | ||
| 4 | EGFR | EGFR Entrez,  Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 625 | 0.230 | 0.4462 | Yes |
| 5 | TNIK | TNIK Entrez,  Source | TRAF2 and NCK interacting kinase | 1197 | 0.145 | 0.4364 | Yes |
| 6 | LCK | LCK Entrez,  Source | lymphocyte-specific protein tyrosine kinase | 1310 | 0.136 | 0.4593 | Yes |
| 7 | GAK | GAK Entrez,  Source | cyclin G associated kinase | 1340 | 0.133 | 0.4879 | Yes |
| 8 | STK3 | STK3 Entrez,  Source | serine/threonine kinase 3 (STE20 homolog, yeast) | 1553 | 0.120 | 0.4995 | Yes |
| 9 | ERBB4 | ERBB4 Entrez,  Source | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 1813 | 0.107 | 0.5044 | Yes |
| 10 | MAP3K4 | MAP3K4 Entrez,  Source | mitogen-activated protein kinase kinase kinase 4 | 2489 | 0.083 | 0.4724 | No |
| 11 | MERTK | MERTK Entrez,  Source | c-mer proto-oncogene tyrosine kinase | 2522 | 0.082 | 0.4890 | No |
| 12 | CSK | CSK Entrez,  Source | c-src tyrosine kinase | 3069 | 0.069 | 0.4635 | No |
| 13 | MINK1 | MINK1 Entrez,  Source | misshapen-like kinase 1 (zebrafish) | 3080 | 0.069 | 0.4787 | No |
| 14 | BLK | BLK Entrez,  Source | B lymphoid tyrosine kinase | 3419 | 0.062 | 0.4675 | No |
| 15 | NEK2 | NEK2 Entrez,  Source | NIMA (never in mitosis gene a)-related kinase 2 | 4483 | 0.045 | 0.3971 | No |
| 16 | STK24 | STK24 Entrez,  Source | serine/threonine kinase 24 (STE20 homolog, yeast) | 5587 | 0.029 | 0.3200 | No |
| 17 | BTK | BTK Entrez,  Source | Bruton agammaglobulinemia tyrosine kinase | 5628 | 0.029 | 0.3236 | No |
| 18 | MAP3K3 | MAP3K3 Entrez,  Source | mitogen-activated protein kinase kinase kinase 3 | 5921 | 0.025 | 0.3072 | No |
| 19 | MAP4K2 | MAP4K2 Entrez,  Source | mitogen-activated protein kinase kinase kinase kinase 2 | 6894 | 0.010 | 0.2356 | No |
| 20 | MAP2K1 | MAP2K1 Entrez,  Source | mitogen-activated protein kinase kinase 1 | 7939 | -0.008 | 0.1581 | No |
| 21 | MAP2K5 | MAP2K5 Entrez,  Source | mitogen-activated protein kinase kinase 5 | 8199 | -0.013 | 0.1414 | No |
| 22 | STK25 | STK25 Entrez,  Source | serine/threonine kinase 25 (STE20 homolog, yeast) | 8561 | -0.021 | 0.1188 | No |
| 23 | MAP4K4 | MAP4K4 Entrez,  Source | mitogen-activated protein kinase kinase kinase kinase 4 | 9922 | -0.055 | 0.0280 | No |
| 24 | STK10 | STK10 Entrez,  Source | serine/threonine kinase 10 | 11218 | -0.103 | -0.0465 | No |
| 25 | SLK | SLK Entrez,  Source | STE20-like kinase (yeast) | 11672 | -0.128 | -0.0514 | No |
| 26 | MAP4K5 | MAP4K5 Entrez,  Source | mitogen-activated protein kinase kinase kinase kinase 5 | 11705 | -0.130 | -0.0239 | No |
| 27 | MAP2K2 | MAP2K2 Entrez,  Source | mitogen-activated protein kinase kinase 2 | 11895 | -0.142 | -0.0054 | No |
| 28 | MAP4K3 | MAP4K3 Entrez,  Source | mitogen-activated protein kinase kinase kinase kinase 3 | 12403 | -0.189 | -0.0003 | No |
| 29 | AXL | AXL Entrez,  Source | AXL receptor tyrosine kinase | 12789 | -0.257 | 0.0299 | No |

