DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class1
GeneSetDASATINIB_FDA
Enrichment Score (ES)0.38568646
Normalized Enrichment Score (NES)1.3051287
Nominal p-value0.08862876
FDR q-value0.6200766
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: DASATINIB_FDA   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1ERBB3ERBB3
Entrez,  Source
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)121.0340.1188Yes
2EPHA1EPHA1
Entrez,  Source
EPH receptor A1940.5450.1758Yes
3PTK6PTK6
Entrez,  Source
PTK6 protein tyrosine kinase 61410.4790.2277Yes
4DDR1DDR1
Entrez,  Source
discoidin domain receptor family, member 12120.4040.2691Yes
5FRKFRK
Entrez,  Source
fyn-related kinase2960.3430.3025Yes
6EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)6250.2300.3041Yes
7EPHB6EPHB6
Entrez,  Source
EPH receptor B67010.2150.3233Yes
8EPHA4EPHA4
Entrez,  Source
EPH receptor A47980.1970.3388Yes
9EPHB2EPHB2
Entrez,  Source
EPH receptor B28680.1850.3550Yes
10TXKTXK
Entrez,  Source
TXK tyrosine kinase10450.1600.3601Yes
11LCKLCK
Entrez,  Source
lymphocyte-specific protein tyrosine kinase13100.1360.3557Yes
12GAKGAK
Entrez,  Source
cyclin G associated kinase13400.1330.3689Yes
13EPHB3EPHB3
Entrez,  Source
EPH receptor B314260.1270.3771Yes
14NEK11NEK11
Entrez,  Source
NIMA (never in mitosis gene a)- related kinase 1115220.1220.3840Yes
15ERBB4ERBB4
Entrez,  Source
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)18130.1070.3742Yes
16TESK1TESK1
Entrez,  Source
testis-specific kinase 118550.1050.3832Yes
17LYNLYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog19740.1000.3857Yes
18JAK3JAK3
Entrez,  Source
Janus kinase 3 (a protein tyrosine kinase, leukocyte)24440.0840.3597No
19MAP3K4MAP3K4
Entrez,  Source
mitogen-activated protein kinase kinase kinase 424890.0830.3660No
20LIMK2LIMK2
Entrez,  Source
LIM domain kinase 227990.0760.3512No
21MAP4K1MAP4K1
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 128490.0740.3560No
22EPHA3EPHA3
Entrez,  Source
EPH receptor A328700.0740.3630No
23TNK2TNK2
Entrez,  Source
tyrosine kinase, non-receptor, 230050.0700.3609No
24YES1YES1
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 130360.0700.3667No
25CSKCSK
Entrez,  Source
c-src tyrosine kinase30690.0690.3723No
26MINK1MINK1
Entrez,  Source
misshapen-like kinase 1 (zebrafish)30800.0690.3795No
27BLKBLK
Entrez,  Source
B lymphoid tyrosine kinase34190.0620.3609No
28CSF1RCSF1R
Entrez,  Source
colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog34540.0620.3655No
29ACVRL1ACVRL1
Entrez,  Source
activin A receptor type II-like 137150.0570.3523No
30BRAFBRAF
Entrez,  Source
v-raf murine sarcoma viral oncogene homolog B137720.0560.3545No
31EPHB4EPHB4
Entrez,  Source
EPH receptor B438790.0540.3527No
32EPHB1EPHB1
Entrez,  Source
EPH receptor B140000.0520.3496No
33FGRFGR
Entrez,  Source
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog41930.0490.3407No
34ACVR1BACVR1B
Entrez,  Source
activin A receptor, type IB43280.0470.3359No
35LIMK1LIMK1
Entrez,  Source
LIM domain kinase 144680.0450.3306No
36BMXBMX
Entrez,  Source
BMX non-receptor tyrosine kinase48260.0400.3079No
37EPHA2EPHA2
Entrez,  Source
EPH receptor A248800.0390.3084No
38ACVR1ACVR1
Entrez,  Source
activin A receptor, type I52300.0340.2857No
39TNNI3KTNNI3K
Entrez,  Source
TNNI3 interacting kinase52740.0330.2863No
40TECTEC
Entrez,  Source
tec protein tyrosine kinase53790.0320.2821No
41MAPK11MAPK11
Entrez,  Source
mitogen-activated protein kinase 1153920.0320.2849No
42EPHA5EPHA5
Entrez,  Source
EPH receptor A554750.0310.2823No
43BTKBTK
Entrez,  Source
Bruton agammaglobulinemia tyrosine kinase56280.0290.2740No
44MAP3K3MAP3K3
Entrez,  Source
mitogen-activated protein kinase kinase kinase 359210.0250.2546No
45RETRET
Entrez,  Source
ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)64710.0160.2146No
46MAPK14MAPK14
Entrez,  Source
mitogen-activated protein kinase 1464920.0160.2150No
47BMPR1BBMPR1B
Entrez,  Source
bone morphogenetic protein receptor, type IB67770.0120.1947No
48ACVR2BACVR2B
Entrez,  Source
activin A receptor, type IIB73820.0020.1488No
49SIK274350.0010.1449No
50SIK37726-0.0040.1233No
51PDGFRBPDGFRB
Entrez,  Source
platelet-derived growth factor receptor, beta polypeptide7824-0.0060.1165No
52PKMYT1PKMYT1
Entrez,  Source
protein kinase, membrane associated tyrosine/threonine 17836-0.0060.1164No
53MAP2K1MAP2K1
Entrez,  Source
mitogen-activated protein kinase kinase 17939-0.0080.1096No
54RAF1RAF1
Entrez,  Source
v-raf-1 murine leukemia viral oncogene homolog 18015-0.0090.1049No
55KITKIT
Entrez,  Source
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog8134-0.0120.0973No
56MAP2K5MAP2K5
Entrez,  Source
mitogen-activated protein kinase kinase 58199-0.0130.0939No
57ACVR2AACVR2A
Entrez,  Source
activin A receptor, type IIA9293-0.0380.0149No
58TYK2TYK2
Entrez,  Source
tyrosine kinase 29438-0.0410.0086No
59HCKHCK
Entrez,  Source
hemopoietic cell kinase9981-0.056-0.0262No
60DDR2DDR2
Entrez,  Source
discoidin domain receptor family, member 210235-0.064-0.0382No
61ADCK310237-0.064-0.0308No
62SRCSRC
Entrez,  Source
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)10776-0.083-0.0623No
63NLKNLK
Entrez,  Source
nemo-like kinase10979-0.093-0.0669No
64ABL2ABL2
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)11090-0.098-0.0641No
65RIPK2RIPK2
Entrez,  Source
receptor-interacting serine-threonine kinase 211349-0.110-0.0710No
66JAK2JAK2
Entrez,  Source
Janus kinase 2 (a protein tyrosine kinase)11530-0.119-0.0710No
67SLKSLK
Entrez,  Source
STE20-like kinase (yeast)11672-0.128-0.0670No
68MAP4K5MAP4K5
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 511705-0.130-0.0544No
69FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES11767-0.133-0.0437No
70MAP3K2MAP3K2
Entrez,  Source
mitogen-activated protein kinase kinase kinase 212210-0.168-0.0580No
71PDGFRAPDGFRA
Entrez,  Source
platelet-derived growth factor receptor, alpha polypeptide12211-0.168-0.0385No
72SIK112319-0.179-0.0260No
73MAP4K3MAP4K3
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 312403-0.189-0.0105No
74TGFBR1TGFBR1
Entrez,  Source
transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa)12447-0.1950.0089No
75ABL1ABL1
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 112463-0.1970.0306No
76ZAKZAK
Entrez,  Source
-12544-0.2090.0487No
Table: GSEA details [plain text format]



Fig 2: DASATINIB_FDA   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: DASATINIB_FDA: Random ES distribution   
Gene set null distribution of ES for DASATINIB_FDA