DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class0
GeneSetPLX-4720_KINOME SCAN
Enrichment Score (ES)-0.39261687
Normalized Enrichment Score (NES)-1.0879381
Nominal p-value0.37179488
FDR q-value0.8622253
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: PLX-4720_KINOME SCAN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1PTK6PTK6
Entrez,  Source
PTK6 protein tyrosine kinase 61410.4790.2019No
2EPHB6EPHB6
Entrez,  Source
EPH receptor B67010.2150.2550No
3NEK11NEK11
Entrez,  Source
NIMA (never in mitosis gene a)- related kinase 1115220.1220.2468No
4LIMK2LIMK2
Entrez,  Source
LIM domain kinase 227990.0760.1834No
5BRAFBRAF
Entrez,  Source
v-raf murine sarcoma viral oncogene homolog B137720.0560.1345No
6FGRFGR
Entrez,  Source
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog41930.0490.1245No
7TGFBR2TGFBR2
Entrez,  Source
transforming growth factor, beta receptor II (70/80kDa)71030.007-0.0935No
8CDK1972630.004-0.1040No
9PDGFRBPDGFRB
Entrez,  Source
platelet-derived growth factor receptor, beta polypeptide7824-0.006-0.1439No
10MAP2K1MAP2K1
Entrez,  Source
mitogen-activated protein kinase kinase 17939-0.008-0.1490No
11RAF1RAF1
Entrez,  Source
v-raf-1 murine leukemia viral oncogene homolog 18015-0.009-0.1506No
12KITKIT
Entrez,  Source
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog8134-0.012-0.1544No
13MAP2K5MAP2K5
Entrez,  Source
mitogen-activated protein kinase kinase 58199-0.013-0.1534No
14RIPK2RIPK2
Entrez,  Source
receptor-interacting serine-threonine kinase 211349-0.110-0.3439Yes
15MAP2K4MAP2K4
Entrez,  Source
mitogen-activated protein kinase kinase 411811-0.136-0.3184Yes
16PDGFRAPDGFRA
Entrez,  Source
platelet-derived growth factor receptor, alpha polypeptide12211-0.168-0.2742Yes
17SIK112319-0.179-0.2029Yes
18ABL1ABL1
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 112463-0.197-0.1262Yes
19RIOK2RIOK2
Entrez,  Source
RIO kinase 2 (yeast)12467-0.198-0.0387Yes
20ZAKZAK
Entrez,  Source
-12544-0.2090.0485Yes
Table: GSEA details [plain text format]



Fig 2: PLX-4720_KINOME SCAN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: PLX-4720_KINOME SCAN: Random ES distribution   
Gene set null distribution of ES for PLX-4720_KINOME SCAN