DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class1
GeneSetNILOTINIB_FDA
Enrichment Score (ES)0.42891753
Normalized Enrichment Score (NES)1.3226978
Nominal p-value0.119791664
FDR q-value0.6254122
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: NILOTINIB_FDA   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1EPHA1EPHA1
Entrez,  Source
EPH receptor A1940.5450.1263Yes
2DDR1DDR1
Entrez,  Source
discoidin domain receptor family, member 12120.4040.2161Yes
3FRKFRK
Entrez,  Source
fyn-related kinase2960.3430.2937Yes
4EPHB6EPHB6
Entrez,  Source
EPH receptor B67010.2150.3156Yes
5EPHA4EPHA4
Entrez,  Source
EPH receptor A47980.1970.3565Yes
6EPHB2EPHB2
Entrez,  Source
EPH receptor B28680.1850.3966Yes
7LCKLCK
Entrez,  Source
lymphocyte-specific protein tyrosine kinase13100.1360.3963Yes
8EPHB3EPHB3
Entrez,  Source
EPH receptor B314260.1270.4187Yes
9NTRK2NTRK2
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 217040.1120.4250Yes
10LYNLYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog19740.1000.4289Yes
11TIE1TIE1
Entrez,  Source
tyrosine kinase with immunoglobulin-like and EGF-like domains 123280.0880.4236No
12MAP4K1MAP4K1
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 128490.0740.4021No
13EPHA3EPHA3
Entrez,  Source
EPH receptor A328700.0740.4186No
14BLKBLK
Entrez,  Source
B lymphoid tyrosine kinase34190.0620.3921No
15CSF1RCSF1R
Entrez,  Source
colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog34540.0620.4047No
16BRAFBRAF
Entrez,  Source
v-raf murine sarcoma viral oncogene homolog B137720.0560.3943No
17EPHB4EPHB4
Entrez,  Source
EPH receptor B438790.0540.3995No
18EPHB1EPHB1
Entrez,  Source
EPH receptor B140000.0520.4032No
19FGRFGR
Entrez,  Source
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog41930.0490.4007No
20EPHA2EPHA2
Entrez,  Source
EPH receptor A248800.0390.3581No
21TNNI3KTNNI3K
Entrez,  Source
TNNI3 interacting kinase52740.0330.3363No
22MAPK11MAPK11
Entrez,  Source
mitogen-activated protein kinase 1153920.0320.3353No
23RETRET
Entrez,  Source
ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)64710.0160.2573No
24MAPK14MAPK14
Entrez,  Source
mitogen-activated protein kinase 1464920.0160.2597No
25MAPK8MAPK8
Entrez,  Source
mitogen-activated protein kinase 868290.0110.2369No
26TEKTEK
Entrez,  Source
TEK tyrosine kinase, endothelial (venous malformations, multiple cutaneous and mucosal)70350.0080.2232No
27PDGFRBPDGFRB
Entrez,  Source
platelet-derived growth factor receptor, beta polypeptide7824-0.0060.1647No
28KITKIT
Entrez,  Source
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog8134-0.0120.1441No
29MAP2K5MAP2K5
Entrez,  Source
mitogen-activated protein kinase kinase 58199-0.0130.1424No
30NTRK3NTRK3
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 38500-0.0190.1244No
31HCKHCK
Entrez,  Source
hemopoietic cell kinase9981-0.0560.0255No
32DDR2DDR2
Entrez,  Source
discoidin domain receptor family, member 210235-0.0640.0218No
33ABL2ABL2
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)11090-0.098-0.0193No
34CDC42BPBCDC42BPB
Entrez,  Source
CDC42 binding protein kinase beta (DMPK-like)12053-0.154-0.0548No
35PDGFRAPDGFRA
Entrez,  Source
platelet-derived growth factor receptor, alpha polypeptide12211-0.168-0.0257No
36ABL1ABL1
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 112463-0.1970.0034No
37ZAKZAK
Entrez,  Source
-12544-0.2090.0485No
Table: GSEA details [plain text format]



Fig 2: NILOTINIB_FDA   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: NILOTINIB_FDA: Random ES distribution   
Gene set null distribution of ES for NILOTINIB_FDA