DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class1
GeneSetBARASERTIB_LINCS
Enrichment Score (ES)0.3504749
Normalized Enrichment Score (NES)1.0342642
Nominal p-value0.3989071
FDR q-value0.7335899
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: BARASERTIB_LINCS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1ERBB2ERBB2
Entrez,  Source
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)1000.5370.1430Yes
2DDR1DDR1
Entrez,  Source
discoidin domain receptor family, member 12120.4040.2477Yes
3EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)6250.2300.2809Yes
4EPHB6EPHB6
Entrez,  Source
EPH receptor B67010.2150.3354Yes
5LCKLCK
Entrez,  Source
lymphocyte-specific protein tyrosine kinase13100.1360.3273Yes
6NTRK2NTRK2
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 217040.1120.3288Yes
7ERBB4ERBB4
Entrez,  Source
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)18130.1070.3505Yes
8TIE1TIE1
Entrez,  Source
tyrosine kinase with immunoglobulin-like and EGF-like domains 123280.0880.3360No
9EIF2AK1EIF2AK1
Entrez,  Source
eukaryotic translation initiation factor 2-alpha kinase 130080.0700.3041No
10KDRKDR
Entrez,  Source
kinase insert domain receptor (a type III receptor tyrosine kinase)31460.0680.3126No
11FLT3FLT3
Entrez,  Source
fms-related tyrosine kinase 334030.0630.3107No
12BLKBLK
Entrez,  Source
B lymphoid tyrosine kinase34190.0620.3270No
13CSF1RCSF1R
Entrez,  Source
colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog34540.0620.3417No
14MUSKMUSK
Entrez,  Source
muscle, skeletal, receptor tyrosine kinase41390.0500.3038No
15FLT1FLT1
Entrez,  Source
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)48820.0390.2583No
16BTKBTK
Entrez,  Source
Bruton agammaglobulinemia tyrosine kinase56280.0290.2097No
17NTRK1NTRK1
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 160970.0220.1803No
18AURKAAURKA
Entrez,  Source
aurora kinase A64270.0170.1600No
19RETRET
Entrez,  Source
ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)64710.0160.1613No
20TEKTEK
Entrez,  Source
TEK tyrosine kinase, endothelial (venous malformations, multiple cutaneous and mucosal)70350.0080.1207No
21PDGFRBPDGFRB
Entrez,  Source
platelet-derived growth factor receptor, beta polypeptide7824-0.0060.0624No
22MKNK2MKNK2
Entrez,  Source
MAP kinase interacting serine/threonine kinase 27841-0.0060.0630No
23KITKIT
Entrez,  Source
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog8134-0.0120.0440No
24MAP2K5MAP2K5
Entrez,  Source
mitogen-activated protein kinase kinase 58199-0.0130.0429No
25PIK3CAPIK3CA
Entrez,  Source
phosphoinositide-3-kinase, catalytic, alpha polypeptide8749-0.0250.0081No
26AURKBAURKB
Entrez,  Source
aurora kinase B8856-0.0270.0077No
27CDK11A9060-0.0320.0012No
28PLK4PLK4
Entrez,  Source
polo-like kinase 4 (Drosophila)10581-0.075-0.0932No
29RPS6KB1RPS6KB1
Entrez,  Source
ribosomal protein S6 kinase, 70kDa, polypeptide 110717-0.081-0.0809No
30CDK7CDK7
Entrez,  Source
cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)11160-0.101-0.0862No
31STK10STK10
Entrez,  Source
serine/threonine kinase 1011218-0.103-0.0616No
32MAP4K5MAP4K5
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 511705-0.130-0.0622No
33PDGFRAPDGFRA
Entrez,  Source
platelet-derived growth factor receptor, alpha polypeptide12211-0.168-0.0536No
34ABL1ABL1
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 112463-0.197-0.0174No
35AXLAXL
Entrez,  Source
AXL receptor tyrosine kinase12789-0.2570.0299No
Table: GSEA details [plain text format]



Fig 2: BARASERTIB_LINCS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: BARASERTIB_LINCS: Random ES distribution   
Gene set null distribution of ES for BARASERTIB_LINCS