DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class0
GeneSetA443654_LINCS
Enrichment Score (ES)-0.26346064
Normalized Enrichment Score (NES)-0.97669363
Nominal p-value0.52319586
FDR q-value1.0
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: A443654_LINCS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1DAPK1DAPK1
Entrez,  Source
death-associated protein kinase 1880.5570.0521No
2MAPK13MAPK13
Entrez,  Source
mitogen-activated protein kinase 131100.5250.1059No
3PRKCDPRKCD
Entrez,  Source
protein kinase C, delta3060.3370.1266No
4PRKCHPRKCH
Entrez,  Source
protein kinase C, eta3560.3090.1555No
5CDK146590.2220.1558No
6PAK1PAK1
Entrez,  Source
p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)6740.2190.1779No
7TAOK3TAOK3
Entrez,  Source
TAO kinase 39710.1700.1732No
8TNIKTNIK
Entrez,  Source
TRAF2 and NCK interacting kinase11970.1450.1713No
9GAKGAK
Entrez,  Source
cyclin G associated kinase13400.1330.1746No
10CAMK1DCAMK1D
Entrez,  Source
calcium/calmodulin-dependent protein kinase ID13870.1290.1847No
11SLC12A7SLC12A7
Entrez,  Source
solute carrier family 12 (potassium/chloride transporters), member 715430.1200.1855No
12STK3STK3
Entrez,  Source
serine/threonine kinase 3 (STE20 homolog, yeast)15530.1200.1975No
13CAMK2ACAMK2A
Entrez,  Source
calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha18010.1070.1899No
14CAMK2GCAMK2G
Entrez,  Source
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma18110.1070.2005No
15DAPK2DAPK2
Entrez,  Source
death-associated protein kinase 218380.1050.2096No
16CSNK1DCSNK1D
Entrez,  Source
casein kinase 1, delta18510.1050.2198No
17RIOK3RIOK3
Entrez,  Source
RIO kinase 3 (yeast)19420.1010.2236No
18AAK1AAK1
Entrez,  Source
AP2 associated kinase 122120.0920.2127No
19ULK2ULK2
Entrez,  Source
unc-51-like kinase 2 (C. elegans)22440.0910.2200No
20CLK3CLK3
Entrez,  Source
CDC-like kinase 323490.0870.2212No
21TAOK1TAOK1
Entrez,  Source
TAO kinase 125520.0820.2144No
22RPS6KA5RPS6KA5
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 526100.0800.2185No
23PIM2PIM2
Entrez,  Source
pim-2 oncogene29560.0710.1997No
24MINK1MINK1
Entrez,  Source
misshapen-like kinase 1 (zebrafish)30800.0690.1976No
25FLT3FLT3
Entrez,  Source
fms-related tyrosine kinase 334030.0630.1796No
26MARK2MARK2
Entrez,  Source
MAP/microtubule affinity-regulating kinase 238340.0550.1526No
27PRKD2PRKD2
Entrez,  Source
protein kinase D239000.0540.1533No
28PRKG2PRKG2
Entrez,  Source
protein kinase, cGMP-dependent, type II40210.0520.1497No
29PIM1PIM1
Entrez,  Source
pim-1 oncogene41360.0500.1463No
30CAMK2BCAMK2B
Entrez,  Source
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta42130.0490.1456No
31CDKL2CDKL2
Entrez,  Source
cyclin-dependent kinase-like 2 (CDC2-related kinase)45480.0440.1248No
32PRKG1PRKG1
Entrez,  Source
protein kinase, cGMP-dependent, type I49360.0380.0992No
33PAK4PAK4
Entrez,  Source
p21(CDKN1A)-activated kinase 450140.0370.0973No
34SRPK3SRPK3
Entrez,  Source
SFRS protein kinase 358600.0260.0355No
35PRKXPRKX
Entrez,  Source
protein kinase, X-linked59930.0240.0279No
36PHKG1PHKG1
Entrez,  Source
phosphorylase kinase, gamma 1 (muscle)62450.0200.0108No
37CSNK1G2CSNK1G2
Entrez,  Source
casein kinase 1, gamma 263280.0180.0065No
38RETRET
Entrez,  Source
ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)64710.016-0.0026No
39PIP4K2B65940.015-0.0104No
40PKN1PKN1
Entrez,  Source
protein kinase N167830.012-0.0235No
41MAP4K2MAP4K2
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 268940.010-0.0308No
42CLK4CLK4
Entrez,  Source
CDC-like kinase 469350.010-0.0329No
43BMP2KBMP2K
Entrez,  Source
BMP2 inducible kinase70290.008-0.0391No
44CLK2CLK2
Entrez,  Source
CDC-like kinase 271810.005-0.0501No
45CDK1972630.004-0.0559No
46GSK3AGSK3A
Entrez,  Source
glycogen synthase kinase 3 alpha73580.002-0.0629No
47AKT1AKT1
Entrez,  Source
v-akt murine thymoma viral oncogene homolog 173870.002-0.0648No
48CSNK1ECSNK1E
Entrez,  Source
casein kinase 1, epsilon7742-0.004-0.0914No
49MAP2K3MAP2K3
Entrez,  Source
mitogen-activated protein kinase kinase 37798-0.005-0.0950No
50MKNK2MKNK2
Entrez,  Source
MAP kinase interacting serine/threonine kinase 27841-0.006-0.0976No
51MELKMELK
Entrez,  Source
maternal embryonic leucine zipper kinase8047-0.010-0.1122No
52PRKACAPRKACA
Entrez,  Source
protein kinase, cAMP-dependent, catalytic, alpha8112-0.011-0.1159No
53KITKIT
Entrez,  Source
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog8134-0.012-0.1163No
54RPS6KA4RPS6KA4
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 48181-0.013-0.1184No
55DYRK1BDYRK1B
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B8200-0.013-0.1184No
56DMPKDMPK
Entrez,  Source
dystrophia myotonica-protein kinase8344-0.016-0.1276No
57CSNK1G1CSNK1G1
Entrez,  Source
casein kinase 1, gamma 18732-0.025-0.1546No
58CSNK2A2CSNK2A2
Entrez,  Source
casein kinase 2, alpha prime polypeptide9758-0.049-0.2277No
59PRKD1PRKD1
Entrez,  Source
protein kinase D19827-0.052-0.2274No
60MAP4K4MAP4K4
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 49922-0.055-0.2289No
61STK17ASTK17A
Entrez,  Source
serine/threonine kinase 17a (apoptosis-inducing)10017-0.057-0.2300No
62LATS1LATS1
Entrez,  Source
LATS, large tumor suppressor, homolog 1 (Drosophila)10025-0.057-0.2245No
63MARK3MARK3
Entrez,  Source
MAP/microtubule affinity-regulating kinase 310374-0.068-0.2439No
64CITCIT
Entrez,  Source
citron (rho-interacting, serine/threonine kinase 21)10420-0.070-0.2399No
65CAMKK2CAMKK2
Entrez,  Source
calcium/calmodulin-dependent protein kinase kinase 2, beta10729-0.081-0.2549Yes
66PIP5K1APIP5K1A
Entrez,  Source
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha10780-0.083-0.2499Yes
67PRKCEPRKCE
Entrez,  Source
protein kinase C, epsilon10801-0.084-0.2425Yes
68PAK2PAK2
Entrez,  Source
p21 (CDKN1A)-activated kinase 210809-0.085-0.2341Yes
69PRKCQPRKCQ
Entrez,  Source
protein kinase C, theta10961-0.092-0.2359Yes
70DAPK3DAPK3
Entrez,  Source
death-associated protein kinase 311066-0.096-0.2337Yes
71GSK3BGSK3B
Entrez,  Source
glycogen synthase kinase 3 beta11131-0.100-0.2281Yes
72CDK7CDK7
Entrez,  Source
cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)11160-0.101-0.2196Yes
73PRKACBPRKACB
Entrez,  Source
protein kinase, cAMP-dependent, catalytic, beta11179-0.102-0.2102Yes
74MYLKMYLK
Entrez,  Source
myosin, light chain kinase11255-0.105-0.2049Yes
75CDK9CDK9
Entrez,  Source
cyclin-dependent kinase 9 (CDC2-related kinase)11631-0.125-0.2203Yes
76HIPK1HIPK1
Entrez,  Source
homeodomain interacting protein kinase 111798-0.135-0.2186Yes
77CDC42BPACDC42BPA
Entrez,  Source
CDC42 binding protein kinase alpha (DMPK-like)11941-0.145-0.2142Yes
78ROCK2ROCK2
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 212033-0.152-0.2051Yes
79CDC42BPBCDC42BPB
Entrez,  Source
CDC42 binding protein kinase beta (DMPK-like)12053-0.154-0.1903Yes
80PKN2PKN2
Entrez,  Source
protein kinase N212286-0.175-0.1895Yes
81MAP4K3MAP4K3
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 312403-0.189-0.1785Yes
82CSNK1G3CSNK1G3
Entrez,  Source
casein kinase 1, gamma 312464-0.197-0.1622Yes
83RIOK2RIOK2
Entrez,  Source
RIO kinase 2 (yeast)12467-0.198-0.1415Yes
84AKT3AKT3
Entrez,  Source
v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)12533-0.207-0.1245Yes
85MAP3K7MAP3K7
Entrez,  Source
mitogen-activated protein kinase kinase kinase 712613-0.221-0.1073Yes
86CDK8CDK8
Entrez,  Source
cyclin-dependent kinase 812650-0.226-0.0862Yes
87AXLAXL
Entrez,  Source
AXL receptor tyrosine kinase12789-0.257-0.0696Yes
88AKT2AKT2
Entrez,  Source
v-akt murine thymoma viral oncogene homolog 212829-0.271-0.0440Yes
89CHUKCHUK
Entrez,  Source
conserved helix-loop-helix ubiquitous kinase12978-0.325-0.0209Yes
90PRKD3PRKD3
Entrez,  Source
protein kinase D313008-0.3450.0133Yes
Table: GSEA details [plain text format]



Fig 2: A443654_LINCS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: A443654_LINCS: Random ES distribution   
Gene set null distribution of ES for A443654_LINCS