| Dataset | NSCLC_collapsed_to_symbols.NSCLC.cls #SEN_versus_RES.NSCLC.cls #SEN_versus_RES_repos |
| Phenotype | NSCLC.cls#SEN_versus_RES_repos |
| Upregulated in class | 0 |
| GeneSet | CHEMBL1241473_ROCHE |
| Enrichment Score (ES) | -0.45311004 |
| Normalized Enrichment Score (NES) | -1.2770344 |
| Nominal p-value | 0.16233766 |
| FDR q-value | 0.6175866 |
| FWER p-Value | 1.0 |

| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | INSR | INSR Entrez,  Source | insulin receptor | 1664 | 0.114 | -0.0512 | No |
| 2 | PTK2B | PTK2B Entrez,  Source | PTK2B protein tyrosine kinase 2 beta | 2042 | 0.098 | -0.0156 | No |
| 3 | BLK | BLK Entrez,  Source | B lymphoid tyrosine kinase | 3419 | 0.062 | -0.0791 | No |
| 4 | CSF1R | CSF1R Entrez,  Source | colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog | 3454 | 0.062 | -0.0410 | No |
| 5 | PLK3 | PLK3 Entrez,  Source | polo-like kinase 3 (Drosophila) | 6755 | 0.012 | -0.2836 | No |
| 6 | MAPK8 | MAPK8 Entrez,  Source | mitogen-activated protein kinase 8 | 6829 | 0.011 | -0.2818 | No |
| 7 | MAP4K2 | MAP4K2 Entrez,  Source | mitogen-activated protein kinase kinase kinase kinase 2 | 6894 | 0.010 | -0.2801 | No |
| 8 | CLK4 | CLK4 Entrez,  Source | CDC-like kinase 4 | 6935 | 0.010 | -0.2769 | No |
| 9 | GSK3A | GSK3A Entrez,  Source | glycogen synthase kinase 3 alpha | 7358 | 0.002 | -0.3075 | No |
| 10 | PTK2 | PTK2 Entrez,  Source | PTK2 protein tyrosine kinase 2 | 8356 | -0.016 | -0.3725 | No |
| 11 | AURKB | AURKB Entrez,  Source | aurora kinase B | 8856 | -0.027 | -0.3923 | No |
| 12 | MAPKAPK2 | MAPKAPK2 Entrez,  Source | mitogen-activated protein kinase-activated protein kinase 2 | 9187 | -0.035 | -0.3943 | No |
| 13 | NEK4 | NEK4 Entrez,  Source | NIMA (never in mitosis gene a)-related kinase 4 | 9362 | -0.039 | -0.3817 | No |
| 14 | DYRK1A | DYRK1A Entrez,  Source | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 10303 | -0.066 | -0.4097 | Yes |
| 15 | MARK3 | MARK3 Entrez,  Source | MAP/microtubule affinity-regulating kinase 3 | 10374 | -0.068 | -0.3702 | Yes |
| 16 | PLK1 | PLK1 Entrez,  Source | polo-like kinase 1 (Drosophila) | 10440 | -0.071 | -0.3284 | Yes |
| 17 | PLK4 | PLK4 Entrez,  Source | polo-like kinase 4 (Drosophila) | 10581 | -0.075 | -0.2894 | Yes |
| 18 | PRKAA1 | PRKAA1 Entrez,  Source | protein kinase, AMP-activated, alpha 1 catalytic subunit | 10906 | -0.089 | -0.2555 | Yes |
| 19 | GSK3B | GSK3B Entrez,  Source | glycogen synthase kinase 3 beta | 11131 | -0.100 | -0.2069 | Yes |
| 20 | FYN | FYN Entrez,  Source | FYN oncogene related to SRC, FGR, YES | 11767 | -0.133 | -0.1674 | Yes |
| 21 | CSNK2A1 | CSNK2A1 Entrez,  Source | casein kinase 2, alpha 1 polypeptide | 11861 | -0.139 | -0.0826 | Yes |
| 22 | CDC7 | CDC7 Entrez,  Source | CDC7 cell division cycle 7 (S. cerevisiae) | 12853 | -0.278 | 0.0250 | Yes |

