DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class1
GeneSetAZ-628_LINCS
Enrichment Score (ES)0.45260274
Normalized Enrichment Score (NES)1.4564375
Nominal p-value0.026455026
FDR q-value0.67266506
FWER p-Value0.998
Table: GSEA Results Summary



Fig 1: Enrichment plot: AZ-628_LINCS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1EPHA1EPHA1
Entrez,  Source
EPH receptor A1940.5450.0880Yes
2MAPK13MAPK13
Entrez,  Source
mitogen-activated protein kinase 131100.5250.1784Yes
3DDR1DDR1
Entrez,  Source
discoidin domain receptor family, member 12120.4040.2411Yes
4FRKFRK
Entrez,  Source
fyn-related kinase2960.3430.2946Yes
5EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)6250.2300.3098Yes
6EPHB6EPHB6
Entrez,  Source
EPH receptor B67010.2150.3416Yes
7EPHA4EPHA4
Entrez,  Source
EPH receptor A47980.1970.3687Yes
8EPHB2EPHB2
Entrez,  Source
EPH receptor B28680.1850.3957Yes
9TXKTXK
Entrez,  Source
TXK tyrosine kinase10450.1600.4102Yes
10TNIKTNIK
Entrez,  Source
TRAF2 and NCK interacting kinase11970.1450.4240Yes
11LCKLCK
Entrez,  Source
lymphocyte-specific protein tyrosine kinase13100.1360.4392Yes
12EPHB3EPHB3
Entrez,  Source
EPH receptor B314260.1270.4526Yes
13LYNLYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog19740.1000.4283No
14TIE1TIE1
Entrez,  Source
tyrosine kinase with immunoglobulin-like and EGF-like domains 123280.0880.4168No
15EPHA3EPHA3
Entrez,  Source
EPH receptor A328700.0740.3884No
16YES1YES1
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 130360.0700.3880No
17CSKCSK
Entrez,  Source
c-src tyrosine kinase30690.0690.3976No
18MINK1MINK1
Entrez,  Source
misshapen-like kinase 1 (zebrafish)30800.0690.4089No
19KDRKDR
Entrez,  Source
kinase insert domain receptor (a type III receptor tyrosine kinase)31460.0680.4158No
20BLKBLK
Entrez,  Source
B lymphoid tyrosine kinase34190.0620.4059No
21CSF1RCSF1R
Entrez,  Source
colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog34540.0620.4141No
22BRAFBRAF
Entrez,  Source
v-raf murine sarcoma viral oncogene homolog B137720.0560.3998No
23EPHB4EPHB4
Entrez,  Source
EPH receptor B438790.0540.4012No
24EPHB1EPHB1
Entrez,  Source
EPH receptor B140000.0520.4012No
25FGRFGR
Entrez,  Source
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog41930.0490.3951No
26RPS6KA6RPS6KA6
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 646850.0420.3651No
27EPHA2EPHA2
Entrez,  Source
EPH receptor A248800.0390.3571No
28FLT1FLT1
Entrez,  Source
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)48820.0390.3639No
29FLT4FLT4
Entrez,  Source
fms-related tyrosine kinase 448980.0390.3695No
30TNNI3KTNNI3K
Entrez,  Source
TNNI3 interacting kinase52740.0330.3468No
31MAPK11MAPK11
Entrez,  Source
mitogen-activated protein kinase 1153920.0320.3435No
32EPHA5EPHA5
Entrez,  Source
EPH receptor A554750.0310.3426No
33RETRET
Entrez,  Source
ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)64710.0160.2697No
34MAPK14MAPK14
Entrez,  Source
mitogen-activated protein kinase 1464920.0160.2710No
35PDGFRBPDGFRB
Entrez,  Source
platelet-derived growth factor receptor, beta polypeptide7824-0.0060.1707No
36MAPK9MAPK9
Entrez,  Source
mitogen-activated protein kinase 97830-0.0060.1714No
37RAF1RAF1
Entrez,  Source
v-raf-1 murine leukemia viral oncogene homolog 18015-0.0090.1590No
38KITKIT
Entrez,  Source
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog8134-0.0120.1520No
39MAP2K5MAP2K5
Entrez,  Source
mitogen-activated protein kinase kinase 58199-0.0130.1494No
40CDK11A9060-0.0320.0895No
41MAP4K4MAP4K4
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 49922-0.0550.0335No
42HCKHCK
Entrez,  Source
hemopoietic cell kinase9981-0.0560.0388No
43CITCIT
Entrez,  Source
citron (rho-interacting, serine/threonine kinase 21)10420-0.0700.0177No
44SRCSRC
Entrez,  Source
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)10776-0.0830.0052No
45ABL2ABL2
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)11090-0.098-0.0017No
46STK10STK10
Entrez,  Source
serine/threonine kinase 1011218-0.1030.0067No
47RIPK2RIPK2
Entrez,  Source
receptor-interacting serine-threonine kinase 211349-0.1100.0159No
48FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES11767-0.1330.0074No
49PDGFRAPDGFRA
Entrez,  Source
platelet-derived growth factor receptor, alpha polypeptide12211-0.1680.0029No
50ABL1ABL1
Entrez,  Source
v-abl Abelson murine leukemia viral oncogene homolog 112463-0.1970.0182No
51ZAKZAK
Entrez,  Source
-12544-0.2090.0486No
Table: GSEA details [plain text format]



Fig 2: AZ-628_LINCS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: AZ-628_LINCS: Random ES distribution   
Gene set null distribution of ES for AZ-628_LINCS