DatasetNSCLC_collapsed_to_symbols.NSCLC.cls
#SEN_versus_RES.NSCLC.cls
#SEN_versus_RES_repos
PhenotypeNSCLC.cls#SEN_versus_RES_repos
Upregulated in class0
GeneSetPKR INHIBITOR_RBC
Enrichment Score (ES)-0.24228595
Normalized Enrichment Score (NES)-0.78726965
Nominal p-value0.8098434
FDR q-value0.9843633
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: PKR INHIBITOR_RBC   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1MST43180.3310.0821No
2RPS6KA2RPS6KA2
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 25900.2370.1375No
3DYRK2DYRK2
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 212300.1420.1346No
4STK3STK3
Entrez,  Source
serine/threonine kinase 3 (STE20 homolog, yeast)15530.1200.1485No
5MAPK3MAPK3
Entrez,  Source
mitogen-activated protein kinase 317660.1090.1674No
6MKNK1MKNK1
Entrez,  Source
MAP kinase interacting serine/threonine kinase 129070.0730.1040No
7FLT3FLT3
Entrez,  Source
fms-related tyrosine kinase 334030.0630.0864No
8PRKD2PRKD2
Entrez,  Source
protein kinase D239000.0540.0660No
9PRKG2PRKG2
Entrez,  Source
protein kinase, cGMP-dependent, type II40210.0520.0736No
10RPS6KA6RPS6KA6
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 646850.0420.0366No
11FLT4FLT4
Entrez,  Source
fms-related tyrosine kinase 448980.0390.0330No
12STK24STK24
Entrez,  Source
serine/threonine kinase 24 (STE20 homolog, yeast)55870.029-0.0099No
13RETRET
Entrez,  Source
ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)64710.016-0.0718No
14MAP4K2MAP4K2
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 268940.010-0.1007No
15CLK4CLK4
Entrez,  Source
CDC-like kinase 469350.010-0.1007No
16CLK2CLK2
Entrez,  Source
CDC-like kinase 271810.005-0.1177No
17GSK3AGSK3A
Entrez,  Source
glycogen synthase kinase 3 alpha73580.002-0.1304No
18CDK5CDK5
Entrez,  Source
cyclin-dependent kinase 574320.001-0.1356No
19MELKMELK
Entrez,  Source
maternal embryonic leucine zipper kinase8047-0.010-0.1792No
20DYRK1BDYRK1B
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B8200-0.013-0.1866No
21MARK4MARK4
Entrez,  Source
MAP/microtubule affinity-regulating kinase 48259-0.014-0.1864No
22CDK18390-0.017-0.1908No
23CDK3CDK3
Entrez,  Source
cyclin-dependent kinase 38440-0.018-0.1887No
24NTRK3NTRK3
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 38500-0.019-0.1870No
25AURKBAURKB
Entrez,  Source
aurora kinase B8856-0.027-0.2052No
26STK11STK11
Entrez,  Source
serine/threonine kinase 119183-0.035-0.2188No
27CDK2CDK2
Entrez,  Source
cyclin-dependent kinase 29409-0.040-0.2230No
28TYK2TYK2
Entrez,  Source
tyrosine kinase 29438-0.041-0.2120No
29PRKD1PRKD1
Entrez,  Source
protein kinase D19827-0.052-0.2250Yes
30CDK6CDK6
Entrez,  Source
cyclin-dependent kinase 69834-0.052-0.2088Yes
31MAP4K4MAP4K4
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 49922-0.055-0.1979Yes
32STK17ASTK17A
Entrez,  Source
serine/threonine kinase 17a (apoptosis-inducing)10017-0.057-0.1867Yes
33BRSK2BRSK2
Entrez,  Source
BR serine/threonine kinase 210749-0.082-0.2160Yes
34CDK4CDK4
Entrez,  Source
cyclin-dependent kinase 410871-0.087-0.1971Yes
35NUAK1NUAK1
Entrez,  Source
NUAK family, SNF1-like kinase, 111032-0.095-0.1789Yes
36GSK3BGSK3B
Entrez,  Source
glycogen synthase kinase 3 beta11131-0.100-0.1543Yes
37STK4STK4
Entrez,  Source
serine/threonine kinase 411518-0.118-0.1459Yes
38MAP4K5MAP4K5
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 511705-0.130-0.1183Yes
39ROCK2ROCK2
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 212033-0.152-0.0944Yes
40MAP3K7MAP3K7
Entrez,  Source
mitogen-activated protein kinase kinase kinase 712613-0.221-0.0676Yes
41PRKD3PRKD3
Entrez,  Source
protein kinase D313008-0.3450.0132Yes
Table: GSEA details [plain text format]



Fig 2: PKR INHIBITOR_RBC   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: PKR INHIBITOR_RBC: Random ES distribution   
Gene set null distribution of ES for PKR INHIBITOR_RBC