Drug Gene Type Source sertraline SLC6A4 IC50=0.000141(uM) D1 PubChem sertraline SLC6A4 IC50=0.003(uM) D1 PubChem sertraline SLC6A3 IC50=0.0324(uM) D1 PubChem sertraline SIGMAR1 IC50=0.0697(uM) D1 PubChem sertraline ADRA2B IC50=0.1814(uM) D1 PubChem sertraline ADRA2A IC50=0.2888(uM) D1 PubChem sertraline SLC6A3 IC50=0.31(uM) D1 PubChem sertraline CHRM5 IC50=0.5073(uM) D1 PubChem sertraline SLC6A2 IC50=0.825(uM) D1 PubChem sertraline SLC6A2 IC50=0.9848(uM) D1 PubChem sertraline CYP2C19 IC50=1.0(uM) D1 PubChem sertraline HTR2C IC50=1.083(uM) D1 PubChem sertraline CHRM1 IC50=1.2882(uM) D1 PubChem sertraline CHRM4 IC50=2.6309(uM) D1 PubChem sertraline HTR2A IC50=2.7409(uM) D1 PubChem sertraline CHRM2 IC50=2.7675(uM) D1 PubChem sertraline HTR2B IC50=3.3935(uM) D1 PubChem sertraline ADRA2C IC50=4.477(uM) D1 PubChem sertraline MC5R IC50=4.598(uM) D1 PubChem sertraline KCNH2 IC50=8.3173(uM) D1 PubChem sertraline DRD1 Potency=10.0(uM) D1 PubChem sertraline IDH1 Potency=10.3225(uM) D1 PubChem sertraline DRD1 Potency=11.2202(uM) D1 PubChem sertraline ATXN2 Potency=14.1254(uM) D1 PubChem sertraline ATXN2 Potency=25.1189(uM) D1 PubChem sertraline DRD1 - D1 PubChem sertraline APAF1 - D1 PubChem sertraline MCHR1 - D1 PubChem sertraline MDM2 - D1 PubChem sertraline MDM4 - D1 PubChem sertraline NPBWR1 - D1 PubChem sertraline UBE2N - D1 PubChem sertraline STK33 - D1 PubChem sertraline SLC5A7 - D1 PubChem sertraline TAAR1 - D1 PubChem sertraline DRD1 Potency=11220.2(nM) D1 ChEMBL sertraline ATXN2 Potency=14125.4(nM) D1 ChEMBL sertraline CFL1 Inhibition=None(Unspecified) D1 ChEMBL sertraline ATXN2 Potency=25118.9(nM) D1 ChEMBL sertraline DRD1 Potency=10000.0(nM) D1 ChEMBL sertraline CDK1 Activity=None(Unspecified) D1 ChEMBL sertraline TP53 Activity=None(Unspecified) D1 ChEMBL sertraline JUN Activity=None(Unspecified) D1 ChEMBL sertraline CFL1 Activity=None(Unspecified) D1 ChEMBL sertraline IDH1 Potency=10322.5(nM) D1 ChEMBL