Drug	Gene	Type	Source
pyrimethamine	DHFR	Ki=0.0308(uM)	D1 PubChem
pyrimethamine	TDP1	Potency=0.2818(uM)	D1 PubChem
pyrimethamine	DHFR	IC50=0.4(uM)	D1 PubChem
pyrimethamine	TDP1	Potency=0.4611(uM)	D1 PubChem
pyrimethamine	TDP1	Potency=0.5309(uM)	D1 PubChem
pyrimethamine	TDP1	Potency=0.6513(uM)	D1 PubChem
pyrimethamine	TDP1	Potency=0.7943(uM)	D1 PubChem
pyrimethamine	IDH1	Potency=0.8199(uM)	D1 PubChem
pyrimethamine	TDP1	Potency=0.9441(uM)	D1 PubChem
pyrimethamine	TDP1	Potency=1.2995(uM)	D1 PubChem
pyrimethamine	TDP1	Potency=3.1623(uM)	D1 PubChem
pyrimethamine	IDH1	Potency=3.1623(uM)	D1 PubChem
pyrimethamine	AR	Potency=4.2163(uM)	D1 PubChem
pyrimethamine	AR	Ratio Potency (uM)=5.35378(uM)	D1 PubChem
pyrimethamine	DHFR	IC50=6.0(uM)	D1 PubChem
pyrimethamine	NFE2L2	Ratio Potency (uM)=8.1191(uM)	D1 PubChem
pyrimethamine	TP53	Potency=8.4127(uM)	D1 PubChem
pyrimethamine	ACP1	IC50_LMPTP(OMFP)_Mean=14.73(uM)	D1 PubChem
pyrimethamine	ACP1	IC50_Mean=16.5(uM)	D1 PubChem
pyrimethamine	ESR1	Potency=23.7101(uM)	D1 PubChem
pyrimethamine	ESR1	ER Potency (uM)=26.6032(uM)	D1 PubChem
pyrimethamine	AR	Potency=39.4861(uM)	D1 PubChem
pyrimethamine	AR	Potency=49.2994(uM)	D1 PubChem
pyrimethamine	CYP19A1	Potency=55.3148(uM)	D1 PubChem
pyrimethamine	AR	AR Potency (uM)=57.4789(uM)	D1 PubChem
pyrimethamine	ACP1	-	D1 PubChem
pyrimethamine	HIF1A	-	D1 PubChem
pyrimethamine	EPAS1	-	D1 PubChem
pyrimethamine	NFKB1	-	D1 PubChem
pyrimethamine	JAK2	-	D1 PubChem
pyrimethamine	MDM2	-	D1 PubChem
pyrimethamine	MDM4	-	D1 PubChem
pyrimethamine	ESR1	-	D1 PubChem
pyrimethamine	CYP1A2	-	D1 PubChem
pyrimethamine	MRGPRX1	-	D1 PubChem
pyrimethamine	TP53	Ratio Potency (uM)=None(uM)	D1 PubChem
pyrimethamine	RELA	-	D1 PubChem
pyrimethamine	TNFRSF10B	-	D1 PubChem
pyrimethamine	IDH1	Potency=819.9(nM)	D1 ChEMBL
pyrimethamine	ACP1	IC50=16500.0(nM)	D1 ChEMBL
pyrimethamine	IDH1	Potency=3162.3(nM)	D1 ChEMBL