Drug Gene Type Source leflunomide HTT Potency=0.3162(uM) D1 PubChem leflunomide CYP1A2 IC50=0.5(uM) D1 PubChem leflunomide CYP3A4 Potency=0.631(uM) D1 PubChem leflunomide AHR AhR Potency (uM)=1.01235(uM) D1 PubChem leflunomide TDP1 Potency=1.0137(uM) D1 PubChem leflunomide AHR Potency=1.1359(uM) D1 PubChem leflunomide RAB9A Potency=1.4125(uM) D1 PubChem leflunomide ATAD5 Potency=2.0588(uM) D1 PubChem leflunomide ATAD5 ATAD5 Potency (uM)=2.7306(uM) D1 PubChem leflunomide ATAD5 Potency=2.7306(uM) D1 PubChem leflunomide SLC6A3 IC50=2.884(uM) D1 PubChem leflunomide TDP1 Potency=4.6109(uM) D1 PubChem leflunomide SLC6A2 IC50=4.63(uM) D1 PubChem leflunomide CYP3A4 Potency=5.0119(uM) D1 PubChem leflunomide ATAD5 ATAD5 Potency (uM)=5.07379(uM) D1 PubChem leflunomide ATAD5 Potency=5.0738(uM) D1 PubChem leflunomide MMP14 EC50=5.65(uM) D1 PubChem leflunomide AHR AhR Potency (uM)=6.60073(uM) D1 PubChem leflunomide SMN2 Potency=7.0795(uM) D1 PubChem leflunomide TDP1 Potency=7.3078(uM) D1 PubChem leflunomide TDP1 Potency=9.2(uM) D1 PubChem leflunomide SMN2 Potency=11.2202(uM) D1 PubChem leflunomide SMN2 Potency=14.1254(uM) D1 PubChem leflunomide SMN2 Potency=15.8489(uM) D1 PubChem leflunomide SMN2 Potency=17.7828(uM) D1 PubChem leflunomide HSPB1 Ratio Potency (uM)=19.4938(uM) D1 PubChem leflunomide NFE2L2 Ratio Potency (uM)=20.4766(uM) D1 PubChem leflunomide MAOA IC50=20.696(uM) D1 PubChem leflunomide AHR Potency=21.6899(uM) D1 PubChem leflunomide NFE2L2 Potency=30.6379(uM) D1 PubChem leflunomide DRD1 - D1 PubChem leflunomide DRD2 - D1 PubChem leflunomide NR0B1 - D1 PubChem leflunomide SENP6 - D1 PubChem leflunomide AHR - D1 PubChem leflunomide CYP3A4 - D1 PubChem leflunomide CASP3 - D1 PubChem leflunomide CYP1A2 - D1 PubChem leflunomide DHODH - D1 PubChem leflunomide SENP7 - D1 PubChem leflunomide SENP8 - D1 PubChem leflunomide CYP3A4 AC50=5011.87(nM) D1 ChEMBL leflunomide CYP3A4 Potency=631.0(nM) D1 ChEMBL leflunomide CYP1A2 AC50=63.1(nM) D1 ChEMBL leflunomide CYP3A4 Potency=5011.9(nM) D1 ChEMBL leflunomide RAB9A Potency=1412.5(nM) D1 ChEMBL leflunomide SMN2 Potency=15848.9(nM) D1 ChEMBL leflunomide HTT Potency=316.2(nM) D1 ChEMBL leflunomide SMN2 Potency=14125.4(nM) D1 ChEMBL leflunomide SMN2 Potency=7079.5(nM) D1 ChEMBL leflunomide SMN2 Potency=11220.2(nM) D1 ChEMBL leflunomide DHODH Inhibition=None(Unspecified) D1 ChEMBL leflunomide SMN2 Potency=17782.8(nM) D1 ChEMBL leflunomide ATAD5 Potency=2058.8(nM) D1 ChEMBL