Tan Lab | DSigDB

Gene Set: D4 : CTD - 1-hydroxypyrene

Collection

D4 : CTD

Chemical Name

1-hydroxypyrene ( From PubChem : 1-HYDROXYPYRENE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
218.25 g/mol	1	1	4.2896	True

Structure

InChI

InChI=1S/C16H10O/c17-14-9-7-12-5-4-10-2-1-3-11-6-8-13(14)16(12)15(10)11/h1-9,17H

InChIKey

BIJNHUAPTJVVNQ-UHFFFAOYSA-N

Links

Gene (52 / 73)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(reaction)			ABCG2		C033146
CTD	increases(secretion)			ABCG2		C033146
CTD	decreases(expression)			AIFM3		C033146
CTD	decreases(reaction)			AR		C033146
CTD	increases(activity)			AR		C033146
CTD	decreases(expression)			ARFGAP2		C033146
CTD	decreases(expression)			ASXL2		C033146
CTD	decreases(expression)			C17ORF70		C033146
CTD	decreases(expression)			C2ORF66		C033146
CTD	increases(expression)			C3		C033146
CTD	decreases(expression)			CLDN15		C033146
CTD	decreases(secretion)			CYP1A1		C033146
CTD	decreases(expression)			DAZAP1		C033146
CTD	decreases(expression)			E4F1		C033146
CTD	decreases(expression)			ERP27		C033146
CTD	affects(binding)			ESR2		C033146
CTD	decreases(reaction)			ESR2		C033146
CTD	increases(expression)			GIMAP6		C033146
CTD	decreases(secretion)			GSTM1		C033146
CTD	decreases(secretion)			GSTP1		C033146
CTD	decreases(expression)			HAGHL		C033146
CTD	decreases(expression)			HIST1H2BI		C033146
CTD	increases(expression)			ITSN2		C033146
CTD	decreases(expression)			JAG1		C033146
CTD	decreases(expression)			LRP12		C033146
CTD	decreases(expression)			MYO15B		C033146
CTD	increases(expression)			NIPAL4		C033146
CTD	increases(expression)			NRIP1		C033146
CTD	affects(binding)			PGR		C033146
CTD	decreases(reaction)			PGR		C033146
CTD	affects(cotreatment)			PGR		C033146
CTD	decreases(expression)			PGR		C033146
CTD	increases(expression)			PHF2		C033146
CTD	increases(expression)			PTGR1		C033146
CTD	decreases(expression)			SLC12A7		C033146
CTD	decreases(expression)			SLC25A34		C033146
CTD	decreases(expression)			SPNS3		C033146
CTD	decreases(activity)			SULT1A1		C033146
CTD	decreases(reaction)			SULT1A1		C033146
CTD	increases(sulfation)			SULT1A1		C033146
CTD	increases(reaction)			SULT1A1		C033146
CTD	increases(metabolic processing)			SULT1A1		C033146
CTD	increases(metabolic processing)			SULT1A2		C033146
CTD	decreases(activity)			SULT1A3		C033146
CTD	decreases(reaction)			SULT1A3		C033146
CTD	increases(sulfation)			SULT1A3		C033146
CTD	increases(reaction)			SULT1A3		C033146
CTD	increases(metabolic processing)			SULT1A3		C033146
CTD	increases(metabolic processing)			SULT1B1		C033146
CTD	decreases(activity)			SULT1E1		C033146
CTD	increases(reaction)			SULT1E1		C033146
CTD	increases(sulfation)			SULT1E1		C033146
CTD	decreases(reaction)			SULT1E1		C033146
CTD	increases(sulfation)			SULT1E1		C033146
CTD	decreases(reaction)			SULT2A1		C033146
CTD	increases(sulfation)			SULT2A1		C033146
CTD	decreases(activity)			SULT2A1		C033146
CTD	increases(reaction)			SULT2A1		C033146
CTD	decreases(expression)			TMEM234		C033146
CTD	increases(glucuronidation)			UGT1A1		C033146
CTD	increases(glucuronidation)			UGT1A10		C033146
CTD	increases(glucuronidation)			UGT1A3		C033146
CTD	increases(glucuronidation)			UGT1A4		C033146
CTD	increases(glucuronidation)			UGT1A6		C033146
CTD	increases(glucuronidation)			UGT1A7		C033146
CTD	increases(glucuronidation)			UGT1A8		C033146
CTD	increases(glucuronidation)			UGT1A9		C033146
CTD	increases(glucuronidation)			UGT2A1		C033146
CTD	decreases(expression)			VN1R4		C033146
CTD	decreases(expression)			ZNF335		C033146
PubChem	AhR Potency (uM)	uM	9.689	AHR	-	GI(Protien) :
PubChem	None	uM		CYP19A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	43.277	ESR1	-	GI(Protien) :

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